Compatibility «Diclofenac» and «Pentalgin»
Between «Diclofenac» and «Pentalgin» found 3 dangerous and 5 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Pentalgin |
✘Diclofenac Analogs | |
✘Pentalgin [Drotaverine+Caffeine+Naproxen+Paracetamol+Pheniramine and more 5Drotaverine, Caffeine, Naproxen, Paracetamol, Pheniramine] Analogs |
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Interactions Diclofenac with Pentalgin
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Dangerous interactions
Diclofenac, like other NSAIDs, can affect the synthesis of renal PH and increase the toxicity of some drugs. Inducers of microsomal liver enzymes or potentially hepatotoxic substances (for example, alcohol, rifampicin, isoniazid, hypnotics and antiepileptic drugs, including phenobarbital, phenytoin and carbamazepine) increase the toxicity of paracetamol, can lead to liver damage even with non-toxic doses of paracetamol, therefore liver function should be monitored. Prolonged co-use of paracetamol and other NSAIDs increases the risk of analgesic nephropathy and renal failure. -
Negative interactions
The clinical significance of this interaction is unknown, however, as with other NSAIDs, concomitant administration of diclofenac and acetylsalicylic acid is usually not recommended due to the possibility of increased side effects. Diclofenac and Naproxen belong to the same pharmaceutical group: Non-narcotic analgesics, including nonsteroidal and other anti-inflammatory drugs. The clinical significance of this interaction is unknown, however, as with other NSAIDs, the simultaneous use of naproxen and acetylsalicylic acid is usually not recommended due to the potential increase in side effects. Increases the effect of indirect anticoagulants (coumarin derivatives) and the likelihood of liver damage with hepatotoxic drugs. Paracetamol and Diclofenac belong to the same pharmaceutical group: Non-narcotic analgesics, including nonsteroidal and other anti-inflammatory drugs. -
Unclear interactions
Paracetamol + Diclofenac analgin and citramon are used together in Dolaren, Panoxen.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
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Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,972,605 possible combinations of drugs and their components were found 412,508 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-04-11
Category - medicine