Compatibility «Relium» and «Pentalginum-N»
Between «Relium» and «Pentalginum-N» found 5 dangerous and 3 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Pentalginum-N |
✘Relium [Diazepam] Analogs | |
✘Pentalginum-N [Codeine+Caffeine+Metamizole sodium+Naproxen+Phenobarbital and more 5Codeine, Caffeine, Metamizole sodium, Naproxen, Phenobarbital] Analogs |
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Interactions Relium with Pentalginum-N
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Dangerous interactions
with hypnotics, sedatives, narcotic analgesics, other tranquilizers, benzodiazepine derivatives, muscle relaxants, general anesthesia, antidepressants, neuroleptics, alcohol - a sharp increase in the depressive effect on the central nervous system;. The combined use of sedatives, such as benzodiazepines or related compounds, which include the drug Sibazone, with opioids, increases the sedative effect, increases the risk of respiratory depression, coma and death due to the additive depressive effect on the central nervous system. Opioid narcotic analgesics (N01AH01) + CNS depressants; hypnotics, neuroleptics, benzodiazepine tranquilizers, etc. => Respiratory depression, bradycardia, deep coma, possible death. When used simultaneously with other drugs that depress the central nervous system (in pm sedatives, hypnotics, some antihistamines, anxiolytics), and alcohol, an additive depressive effect is possible. Hypnotics, Barbiturates, glutetimide, nitrazepam, etc. + Antihistamines with a sedative component (diphedrol, diprazine, suprastin), antihypertensive agents (clofelin, reserpine), neuroleptics (aminazine, haloperidol), tranquilizers (sibazone) => Increased hypnotic effect up to toxic. -
Negative interactions
It potentiates the effects of alcohol, anticonvulsants and hypotensive drugs, neuroleptics, tricyclic antidepressants, analgesics (in pm narcotic analgesics), hypnotic drugs, general anesthetics, muscle relaxants, antihistamines with sedative effect. Interaction with opioids. The same effects are observed when taken simultaneously with other CNS depressants. -
Positive interactions
Sedatives and tranquilizers enhance the analgesic effect of sodium metamizole. -
Unclear interactions
Analeptics, psychostimulants - reduce activity. monoamine oxidase inhibitors, respiratory analeptics, psychostimulants - reduce the activity of diazepam. With sedatives and tranquilizers. Anxiolytics and sleeping pills - clonazepam.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,972,605 possible combinations of drugs and their components were found 412,508 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-04-11
Category - medicine