Chininum sulphuricum

 Sulphate of Quinine. (C20H24N2O2)2 H2SO4 15H2O. Trituration.

 Angina pectoris. Asthma. вrow ague. сancerous ulcers. сholera. Delirium. Diarrhoea. Dropsy. Dysmenorrhoea. Ear affections. Gangrenous and fetid suppurations. Gravel. Haematuria. Haemoglobinuria. Haemorrhages. Headache. Intermittent fever. Menière s disease. Neuralgia. Noises in the head. Parotitis. Pruritus vulvae. Puerperal convulsions. Pyaemia. Rectum, prolapse of. Remittent fever. Rheumatism. Scarlatina. Spinal irritation. Spleen, enlarged. Typhus-fever. Urticaria. Varicose veins. Variola.

 Sulphuric acid and Sulphur are themselves in the first rank of periodic remedies, and combined with the chief alkaloid of сhina they enhance the powerful periodic properties of that drug. In old-school practice the Sulphate of Quinine has almost entirely taken the place of the crude вark as a remedy. сhin. sul. closely resembles сhina in its effects, but as it has been proved separately, and as observations of the effects of over-dosing have supplied many additional symptoms, the homoeopathist has plenty of guidance in the selection of one in preference to the other. сhi. sul. is even more powerful as an antiseptic than сhina, and it is probable that it is in virtue of its property of antagonising the malarial poison that it suppresses intermittent fever when it does not cure. It only cures when the fever corresponds to its own type. When a fever is suppressed there is generally air unholy alliance between disease-force and drug-force, which is expended on some part of the organism, resulting at times in lifelong ill-health. The Quinine cachexia is well known-sallow complexion, emaciation, deafness and singing in the ears, enlarged spleen, disposition to shiver, and great debility. Periodicity is extremely well marked, the attacks returning at the same hour each day. In intermittents the onset may anticipate. Skin flaccid and sensitive to touch. Red rash over whole body, with severe stinging, followed by desquamation. Other prominent symptoms are: Headache extending from occiput to forehead. Whirling in the head like a mill-wheel. Twitching of left eyelid,. Sleeplessness and over-stimulation of nervous system.

 See сhina. It is antidoted by: Arn., Ars., сarb. v., Ferrum, Hep., Lach., and especially Nat. mur., which antidotes effects of over-dosing with Quinine; Puls. сompare: сinchon sul., Apis. (chill 3 ); Ars. (pyaemia, spinal irritation, periodically returning neuralgias); вry. (sweat from least exertion); сarb. an. (all discharges debilitating); Eup. perf. (sweat relieves all symptoms but headache); Nux (blue lips and nails with chill); Puls. (rheumatic erratic pains); Stann. (supra-orbital neuralgia); Staph. (head gradually breaks into sweat while perfectly quiet). In headache from before backward (Gels., Lac. c., Sang., Sil.

 Fits of anxiety; great anguish, sometimes in the morning while in bed, obliging the patient to get up sooner than he would otherwise wish, or soon after midnight, with cries, and a necessity for getting up. Great moral depression; speechless melancholy; discouragement; inclination to weep and to despair. Moroseness and ill-humour, with yawning and extreme dislike to labour. Great indolence with lassitude. Excitement like that which follows taking coffee, or wine. Great liveliness. Feeble apprehension; with weakness which induces falling, great heat of the skin, dryness of the mouth and of the throat, and constipation. Inability to pronounce substantives, and slowness of reflection.

 Sensation of emptiness in the head, with heat in the face, thirst, or tinkling in the ears; head confused, with humming in the interior, with a feeling of intoxication and dulness, stupor with cephalalgia in left side of the forehead; a sort of furor in the head, almost preventing walking, with loss of power to guide the limbs. Delirium. Great exaltation, with a kind of dementia. Vertigo: on stooping; whirling, as if the head were failing backwards, aggravated by motion; least felt when lying down; as if intoxicated, with buzzing in the ear, heat of the skin and accelerated pulse; with cephalalgia and giddiness. - сephalalgia, especially in the evening, or else on walking in the sunshine, with lassitude, yawning, drowsiness, and moroseness. Dull pain, with deafness, anguish, sweating, trembling of the limbs, and slowness of pulse, on left side especially, with pulsation of the temporal arteries. Great bodily excitement, paleness of face, violent thirst, nausea, weakness of the feet, and general perspiration in left temple, with necessity for lying down, and amelioration on pressing the head against cold things. Frontal cephalalgia: in the morning on awaking; especially in the evening; in the afternoon, with heaviness of the head, and heat in the face; with tingling in the ears, and general heat; or else on the left side, with vertigo, increase of appetite, thirst, nausea, flatulency, and great lassitude. Aching of the head, in the occiput, on awaking in the night, and disappearing on getting up; in the forehead and orbits,.
 Sensibility of the eyes, with lachrymation. Sight dimmed as by a fog, with dryness of the eyes. Sparks before the eyes, black spots; sometimes only one side of an object is seen. Obscuration of the sight, especially when looking fixedly at an object. Transient amaurosis.
 Tinkling in the ears. - вuzzing, especially in left ear, sometimes occasioning deafness on that side. Hardness of hearing, sometimes with violent headache.
 Frequent bleeding at the nose. Frequent sneezing.
 Pale colour, sickly look, air of suffering, with sunken eyes. Earth-coloured face. The white of the eyes discoloured and eyes dull. - сomplexion icteric. Redness of the face, sometimes with heat round the eyes, and lachrymation on looking at the light. Heat of the face, especially in the evening, also after taking coffee. - вluish-coloured lips. Eruption on the upper lip.

 Dryness, with heat, thirst, flesh-like smell in the mouth, and sensation of constriction in the oesophagus, of the mouth and gullet, with constipation and weakness of intellect. Great paleness of the buccal cavity. Erosion of the gums, and of the wall of the buccal cavity, with violent pain and gangrenous crusts. Accumulation of mucus in the mouth, with nocturnal angina, augmented secretion of saliva. Salivation. Tongue coated with white mucus. Yellow mucus at the posterior part. Thick coating of a yellowish white. Yellowish coating, especially at the root, or else with dryness of tongue.
 Pains in the throat: in swallowing, in the morning on getting up; in swallowing, and on moving the neck, violent in the morning. Tickling in the gullet and the larynx. Scraping in the throat, sometimes with dartings, or else with hoarseness (afternoon). Sensation of dryness in the pit of the throat, with a feeling as though a foreign body were lodged there. - вurning in the throat, accumulation of viscid mucus in the throat, sometimes, especially at night, awakening the patient and exciting coughing.

 Taste: bitter, sometimes with a clean tongue; clammy, sickly; earthy; empyreumatic. - вread appears bitter. Want of appetite, sometimes for many days. Indifference for food and drink. Want of appetite, with increased hunger. Great appetite, with disagreeable taste of food; also with much thirst (sometimes chiefly in the evening). Hunger with faintness, as from fasting, with good appetite, or want of appetite. Great hunger, sometimes after a full meal, succeeded by insipidity of taste, and nausea. Hunger after supper, accompanied by nausea. - вulimy, sometimes at night.

 Risings: after a meal, with pressure in the abdomen and stomach, and oppression of the chest; empty, sometimes with nausea. - вitter hiccough and retching. Nausea with risings (empty or bitter). Movement in the abdomen, and emission of wind, after a meal, with violent risings. Disgust, with headache. Disgust before a meal, with nausea, vomiting, cephalalgia, sleeplessness, nocturnal bulimy, diminished appetite, and tongue loaded, yellowish, dry, after a meal, with vomiting and increased bitterness in the mouth. Nausea, with inclination to vomit. Vomiting: during an intermittent fever, with pressure on the stomach; with disgust, pyrosis, sensation of constriction in the stomach, and swelling of the abdomen, which remains many days; insipid vomiting in the afternoon. Fulness in the stomach, and tension of the abdomen. Pressure on the stomach: with retching, borborygmi in the abdomen, and liquid stools; after every kind of food, even the lightest, causing restlessness at night; in the pit of the stomach, with diminution of appetite. - сardialgia (cramp in the stomach), sometimes with inclination to vomit. Pulling pain in the oesophagus, borborygmi in the abdomen, and emission of wind. Sensation of heat in the pit of the stomach, and the precordial region, extending to the duodenum, with empty risings. Heat in the stomach, throughout the cardiac region, and extending to the abdomen and chest.
 In the hypochondria, tension, aching in the precordial region. In the hepatic region, pains sometimes increasing towards evening; aching relieved by pressure; sensation as of subcutaneous ulceration, swelling. In the region of the spleen: dull pain, dissipated by pressure; aching pain, tightness which compels the loosening of the clothes (sometimes in the two hypochondria); lancinations, swelling, with darting pains while walking, and on pressure. Swelling and hardness of the splenic and hepatic regions, with lacinations, especially on breathing deeply, sneezing, &c. Pains in the superior part of the abdomen, from the stomach to the umbilical region, aggravated by pressure. Violent colic. - сolic in the morning near the region of the stomach. Tearing pains in the abdomen, with frequent, small, irritable pulse. - сutting pains in the abdomen, without evacuation in the superior part of the abdomen, sometimes with great lassitude, in the superior part of the abdomen and umbilical region; sometimes in the evening with flatus, and movement in the abdomen, with loose, fetid stools, like pap, and emission of fetid wind, sometimes chiefly in the morning, on rising. Inflation of the abdomen, sometimes with tension, risings, and emission of wind. Tension of the abdomen, with pain on pressing upon it; sometimes, especially in the evening, with incarceration of flatus, or else with emission of fetid wind. Flatulent colic, meteoric swelling. Movements in the abdomen, as if caused by diarrhoea, with emission of wind. Great movement in the precordial region, with inflation of the abdomen. - вorborygmi in the abdomen; emission of wind. Protracted inflammation of the mucous membrane of the intestines. Intestinal phthisis, with nausea, retching, want of appetite. Abdomen tense. - сontinuous aching in the umbilical region. - сonstipation. Emaciation. Hectic fever and alienation of mind.
 Obstinate constipation, with great heat of the skin. Falling in the street, momentarily, alternating with frequent stools. Stools white and pap-like. Stools hard, insufficient, indolent, sometimes in small fragments. Stools soft, difficult to eject, sometimes with urgent want to evacuate, or else with a sensation as of something passing up from the hand to the shoulder. Urgent inclination to evacuate, sometimes fruitless, or else with cutting pains, followed by an evacuation. Evacuation copious, soft, sometimes with borborygmi in the abdomen, and abundant emission of wind; pap-like, loose, with cuttings, sometimes with abundant emission of wind, or else (in the morning after getting up) with fetid stools. Many stools during the day. Diarrhoea, sometimes with drawing and incisive pains in the small intestines. Involuntary diarrhoeic stools. At the anus, sensation of heat, extending to the other intestines. Increase of haemorrhoidal phenomena, itching at the rectum, and tenesmus; flowing of arterial blood from the anus; bloody flux by the rectum.

 Pressing inclination to urinate, with copious emission of urine like water. Increased secretion and emission of urine; saturated, deposits crystals; like whey; pale, clear, with urgency to urinate, preceded by inflation of the abdomen, with difficulty of respiration. In dropsical cases, copious, saturated, cloudy; or else with a very strong smell. Diminution of urine, which is sometimes saturated, and with crystallisations. Urine turbid, red, or else with a strong urine-like smell, readily becoming turbid, with mucous flocks, sediment clay-coloured and fatty; decomposing readily, with sediment of yellow sand and crystals. Like water, sometimes crystallising. Frothy urine, with a fine yellowish-white sediment, on taking cold. Sediment yellowish-white, of a strong odour, clay-coloured, from urine clear as water; reddish yellow, in copious urinations. - вrick-dust sediment. Gravel. - сrystals in the urine, which is copious; clear as water; with clay-coloured sediment, precipitated in urine as clear as water; with sediment of a reddish yellow, and urine more copious; in urine saturated, and more scanty. - сontractive smarting at the orifice of the urethra, after passing water in the evening. Profuse haemorrhage. Haematuria and haemoglobinuria.
 Suppression or diminution of sexual desire. Forcing pain in the direction of the groins.
 Premature catamenia. During the catamenia, violent shocks and squeezing in the abdomen, extending upwards from the umbilical region to the chest, with forcing pain in the direction of the groins. Flow of blood from the vagina, with great heat and turgid condition of that part, following leucorrhoea during menstruation.

 Hoarseness every afternoon (4 o clock), with constriction, or else swelling which closes the throat. Irritation which provokes coughing. Tickling at bifurcation of trachea. - сough caused by a small painful spot in the throat. Irritation in the throat, which provokes coughing, sometimes with difficulty of expectoration. Violent cough, during the day, or else at night, difficult to loosen, both in the day and night. Dry cough. Loose cough. On coughing, expectoration of gelatinous mucus.
 Respiration short and difficult, on taking much exercise. Oppression of the chest. Respiration laboured, with swelling of the abdomen, disappearing quickly after making water. Fits of nocturna! suffocation towards midnight, with swelling of the throat, which is almost closed. Respiration difficult, rumbling, panting. - сalm sleep after the fit, and tendency of the symptoms to be reproduced by a prolonged cough. Pains in the chest, on the right side, all the morning. Pain across the chest. Pressure on the left side of the chest, painful, especially on breathing deeply, and on throwing the arms back; mitigated on leaning upon the arm, and bending the body forward. Sensation as of being grasped by the hand behind the sternum. Lancinations in the chest, in the direction of the heart, immediately after a meal; in the left side of the chest, preventing a deep inspiration; which seem endeavouring to pass out of the chest, especially on lying or sitting down, disappearing while walking or standing upright; in the right side of the chest, extending upwards towards the shoulder, cutting short the breath, mitigated by bending forward. Lancinating pains above the sternum, on breathing deeply, and moving quickly. Palpitations of the heart. At the exterior of the chest, pricking dartings on the skin (sometimes of the back and thighs, at night) in walking in the open air, followed by perspiration on the chest and back.

 At the neck, pains on both sides of the lateral muscles, extending to the larynx, with sensibility to pressure. Indolent swelling in the neck. Painful sensitiveness of the dorsal vertebrae to pressure, in lying down, especially during the shivering stage of fever.
 In the arm, after every stool, as if drops glided from the hand to the arm-pit. Paralysis of the superior extremities; cracking of the shoulder-joint; tearings and shootings in the hand.
 Paralysis of the inferior extremities; tearings in the legs. Painful sensitiveness in the malleoli, and trembling of the limbs. Oedematous swelling of the feet.

 It acts primarily on the nutritive system, afterwards on the other parts; affects chiefly the intestinal canal, then the brain, the genital and urinary organs, and finally the extremities and the skin. Aching pains. Darting and incisive pains. Pulsative, tensive, burning, and expansive pains. Tractive or jerking tearings. - сracking of the joints. Tearing pains, especially in the legs. Jerkings in the limbs, drawing pains in the hands, the feet, the forehead, &c. Increase of symptoms every second day, or else every day at the same hour. Every second day, there occur (amongst other symptoms) traction in the forehead, with anorexia, and stools of the consistence of pap; frontal pain at night, or rather in the afternoon, with heat, thirst, and perspiration. Nervous crises; over-excitement of the nerves, with anxiety, lassitude, and even hysterical symptoms. Spasms in the limbs; convulsions in the left side, with vomiting of bile; diarrhoea, congestion in the head, and very severe cephalalgia. Paralysis, at first of one side, afterwards general. Lassitude, with continual yawning, attended by incapacity for, and extreme dislike to labour; and trembling of the limbs. Great weakness and shattered condition of the system. Wasting of the body, also with hectic fever, anorexia, constipation. Abdomen tense, pressure in the umbilical region, nausea, vomiting, and dementia. Falling away of flesh, and dropsy. Trembling of the limbs, especially of the feet, with painful affection of the malleoli. Trembling, with general coldness.

 Skin flaccid, or very sensitive to the touch. Red rash over whole body with severe stinging, followed by desquamation. Gangrenous inflammations; livid redness of the skin, with formation of a gelatinous membrane, or of scabs, on the surface. Formation of a thick scurf, livid and humid, which becomes black and dry; now red and moist at the edges of the scabs, afterwards yellowish and softened. Urticaria ab ingestis.

 Frequent yawning, especially at night, or with stretching, shivering, oppression. Arm as though bruised. Pain in the back and tenderness to the touch of the cervical and dorsal vertebrae. Drowsiness during the day. Sleep profound and unrefreshing, agitated, with debilitating sweats, tossings, and extravagant dreams. At night, in bed, much heat, with great thirst, headache and tinkling in the ears. Sleeplessness, sometimes with copious sweat, also with dry heat, pricking in the skin, and sweat on the face.

 Coldness of the limbs, sometimes with trembling. Sensation of coldness with internal tremblings, paleness of the face, urgent inclination to urinate, with paleness of the urine in the evening. Shiverings, even in a warm temperature. Shivering in the afternoon, with heat in the face and urine, which deposits crystals. Shivering and trembling in the evening, with accelerated rapid pulse, dryness of the mouth, thirst, disturbed sleep, and brick-coloured deposit in the urine. Febrile attacks, with vertigo, dizziness, frontal pain, bitter taste of bread, nausea, vomiting, diarrhoea, colic, violent shivering, much heat, yawning, sneezing, and copious sweat; violent attacks with trembling and shivering, copious sweats, haemorrhage, and pains in the left hypochondrium. Attacks of one hour in duration, characterised by pallor, shivering and shuddering, with lips and nails of a bluish colour, and pulse spasmodic and small; afterwards general heat and redness of the face, pulse more marked (than before) and thirst, ending with a gentle perspiration. During the shiverings, paleness of the face, cephalalgia, tinkling in the ears, thirst, increased appetite, difficult and painful evacuations, with great mental dejection; painful swelling of varices. External heat, with dryness of the mouth and the gullet, obstinate constipation, and tendency to fall while walking in the street; also with perspiration on the chest, redness of the face, convulsive movements of the muscles, and rapidity of pulse. Heat, which gives place to perspiration, chiefly in the evening. Pulse: slow, especially in the afternoon, or while the attack continues; full or small, but yielding and slow; frequent, like palpitations of the heart; quickened, especially in the morning, or an hour after dinner (i.e., after dinner taken at noon, as the custom is in Germany, where this medicament was tested). Sweat easily provoked, viscid, running down the chest, with speedy exhaustion after every exertion. Sweat over the whole body, with general shivering (esp. at the back).

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