Description Source
Encyclopedia of Pure Materia Medica - TF AllenAdditional facts
An alkaloid, obtained from Atropa belladonna. Formula, с17H23NO3.
Preparation: Triturations.
(Most of the poison-symptoms were obtained from the sulphate of Atropine.
Preparation: Triturations.
(Most of the poison-symptoms were obtained from the sulphate of Atropine.
Mental
Mind.
EMOTIONS: Frenzied with excitement. A long chill, followed by delirium, which had some resemblance to the sub-delirium of certain typhoid fevers.
Immediately upon closing the eyes, after retiring, the mind would become filled with strange and fanciful ideas, rambling, incoherent speech, spectral illusions, with frequent fits of wild, uncontrollable laughter.
The delirium and spectral illusions continued through the night, during which time I fancied myself afflicted with epilepsy, and was constantly fearful lest others should discover my unfortunate condition; was nearly oblivious to all that transpired during the latter part of the night, but know from the bruises received and the sensations of pain occasionally experienced upon coming in contact with a stove, chair, table or some solid body, that it was passed in the wildest delirium (first day).
Busily influenced by pleasing illusions and delusions, meddling with everything in his way, picking at and handling imaginary objects in the air, and accompanying his acts by muttering and smiling, or with loud chattering, interrupted by subdued laughter.
Frightful phantasies.
Spectral illusions (first night).
On lying in bed, began to pick at specks and at the air.
Picking at the bedclothes as if searching for something lost, with confused mutterings (first night).
At times, while it seemed to him that he was fully conscious, saw persons at the bedside and slowly reached out to grasp them, but his hand would pass through the object and no sense of touch tell him that there was any material in the apparition; saw books and newspapers and tried to grasp them, but they would either recede or the hand would come in contact with them and feel nothing.
Mind has been wandering considerable of the time through the afternoon; often thinks he is spoken to and answers imaginary questions (after ten hours).
The symptoms during this period, six to nine hours after, exactly resembled those of delirium tremens.
There was incessant rambling, great restlessness, a grasping at imaginary objects, and occasional screaming from fright.
The character of the delirium varied; sometimes the child saw objects which frightened him, and the utmost terror was depicted on his countenance, and he clung to his nurse’s neck, or threw himself violently in different directions as if to escape them.
Later, the delusions were of a more pleasurable kind, imaginary playing with toys, drawing, eating, etc.
Frequently, through the forenoon, thought that persons in the room spoke to me, and would carry on conversion with these imaginary begins (second day).
Now and then, he seems to have almost a consciousness of what transpires about him, so that, at times, he returns an answer, when addressed whose commencement shows that he understood, but which passes into irrelevant, senseless talk.
As to my sensations, they were not blunted, but I misinterpreted them.
Thus, I felt a wet cloth on my head, but supposed I had been out in the rain without my hat; and a dose of bromide of potassium given to me I recognized as a saline solution, but imagined it was mineral water from the Airthry Springs which I had tasted on the spot some ten days before.
The patient is busied with subjects which at other times occupy his mind, politics and struggles consequent on his relations in life.
Very restless and delirious, talking constantly about his affairs apparently.
Meddlesome delirium, and he will require attention to prevent him from getting out of bed.
When put to bed, he struggles to rise almost incessantly.
He jumped out of bed several times, and insisted on dressing himself.
Keeps his eyes closed, but on being spoken to loudly looks at speaker; caught perhaps one word or a part of a sentence, repeated it, and said, ‘Oh, I shall lose my train .
Expostulates with those who try to lead him to bed; says he will lose the train, that all things are packed up, and that he must start immediately.
Resists when being undressed, saying continually that he will lose the train.
Tries to put on his trousers and fasten and fasten his necktie.
I imagined I had to go off by a railway train, which started at ten in the morning, and that the hour was approaching, whilst I had nothing ready for the journey; and I believed that I wished to dress and to pack my things, but was thwarted and prevented by the people about me.
At length I was persuaded that it was too late to catch the train, and agreed to sat till evening.
Insisted repeatedly that her blood did not circulate, and that her feet must be put into warm water or she should die.
Talked confusedly and almost unintelligible nonsense, on waking in morning.
Agitation and delirium, worse at night.
Violent delirium and restlessness (after four and a half hours).
Delirious and a little drowsy.
Delirium followed by stupor.
Loud cries without any pains.
Sadness.
Mentally either very sad, depressed in constant anxiety and restlessness, fearful of misfortune, or angry and inclined to be alone, seldom lively.
Apprehensiveness followed his internal restlessness, and soon amounted to great anxiety.
Not quarrelsome or ill-tempered, but attempts to reason.
Very sensitive.
Constantly fretful.
I then became sensible that I was lifted into bed, and ordered on no account to rise, which I thought a most unreasonable restraint; especially as I was tormented with irritation in the bladder, and almost incessant desire to pass urine, which was in very small quantity.
Was generally restless and unmanageable, refusing to answer, to swallow, or to be examined; appeared profoundly intoxicated (after one hour).
Evidently unconscious and very irritable, striking his mother when she took him from the nurse (after one hour).
Incoherent quarreling (after eight hours).
Morose, quarrelsome the whole day, everything went wrong; trifles which usually passed unheeded irritated him to anger.
Desire to scold and quarrel.
INTELLECT: Upon making vigorous efforts to arouse him, he also exhibited some signs of consciousness.
When he closes his eyes the mind becomes confused and he sees all sorts of spectres (after thirteen hours).
Mind confused; would commence a sentence, and forget what she wished to say.
Feel as though awakened from a dream (second day).
Appears dull and stupid (after ten hours).
Has only vague ideas of anything she said, or of what transpired that evening.
When left to himself he did not appear to drop off into coma as do those who have taken opium, but would occasionally open his eyes with a vacant, amaurotic expression, and turn his head from side to side.
At first, a slowness of intelligence; ideas and replies are imperfect and indifferent.
Dull and stupid all the afternoon (after six hours).
Cannot be made to understand where he is, that he is ill, or that he must keep quiet.
First, indolence of mind, then vertigo, and a condition of commencing intoxication.
Feels dull and not inclined to move about or to converse (after one hour).
Indisposition for mental labor.
No desire for his ordinary mental labor.
Prover was dull and disinclined to study for several days.
For several days a difficulty of fixing upon anything for more than a few minutes at a time. The prover was absent-minded at intervals for several days, and found difficulty in fixing his mind upon any subject for more than a few minutes at a time.
Loss of memory (after eight hours).
His memory is wrong, inasmuch as he thinks that what really happened from the eleventh to the twelfth, took place in the night from the tenth to the eleventh (after sixth day).
Am absent-minded and forgetful; when conversing often partly finishing a sentence; was often obliged to stop and inquire what I had been saying (second day).
He recognizes, momentarily, members of the family; apparently notices when the door opens or one is busy about him but, when spoken to, often turns his head to the wrong side.
Unconscious, with incoherent speaking at intervals.
Comatose.
EMOTIONS: Frenzied with excitement. A long chill, followed by delirium, which had some resemblance to the sub-delirium of certain typhoid fevers.
Immediately upon closing the eyes, after retiring, the mind would become filled with strange and fanciful ideas, rambling, incoherent speech, spectral illusions, with frequent fits of wild, uncontrollable laughter.
The delirium and spectral illusions continued through the night, during which time I fancied myself afflicted with epilepsy, and was constantly fearful lest others should discover my unfortunate condition; was nearly oblivious to all that transpired during the latter part of the night, but know from the bruises received and the sensations of pain occasionally experienced upon coming in contact with a stove, chair, table or some solid body, that it was passed in the wildest delirium (first day).
Busily influenced by pleasing illusions and delusions, meddling with everything in his way, picking at and handling imaginary objects in the air, and accompanying his acts by muttering and smiling, or with loud chattering, interrupted by subdued laughter.
Frightful phantasies.
Spectral illusions (first night).
On lying in bed, began to pick at specks and at the air.
Picking at the bedclothes as if searching for something lost, with confused mutterings (first night).
At times, while it seemed to him that he was fully conscious, saw persons at the bedside and slowly reached out to grasp them, but his hand would pass through the object and no sense of touch tell him that there was any material in the apparition; saw books and newspapers and tried to grasp them, but they would either recede or the hand would come in contact with them and feel nothing.
Mind has been wandering considerable of the time through the afternoon; often thinks he is spoken to and answers imaginary questions (after ten hours).
The symptoms during this period, six to nine hours after, exactly resembled those of delirium tremens.
There was incessant rambling, great restlessness, a grasping at imaginary objects, and occasional screaming from fright.
The character of the delirium varied; sometimes the child saw objects which frightened him, and the utmost terror was depicted on his countenance, and he clung to his nurse’s neck, or threw himself violently in different directions as if to escape them.
Later, the delusions were of a more pleasurable kind, imaginary playing with toys, drawing, eating, etc.
Frequently, through the forenoon, thought that persons in the room spoke to me, and would carry on conversion with these imaginary begins (second day).
Now and then, he seems to have almost a consciousness of what transpires about him, so that, at times, he returns an answer, when addressed whose commencement shows that he understood, but which passes into irrelevant, senseless talk.
As to my sensations, they were not blunted, but I misinterpreted them.
Thus, I felt a wet cloth on my head, but supposed I had been out in the rain without my hat; and a dose of bromide of potassium given to me I recognized as a saline solution, but imagined it was mineral water from the Airthry Springs which I had tasted on the spot some ten days before.
The patient is busied with subjects which at other times occupy his mind, politics and struggles consequent on his relations in life.
Very restless and delirious, talking constantly about his affairs apparently.
Meddlesome delirium, and he will require attention to prevent him from getting out of bed.
When put to bed, he struggles to rise almost incessantly.
He jumped out of bed several times, and insisted on dressing himself.
Keeps his eyes closed, but on being spoken to loudly looks at speaker; caught perhaps one word or a part of a sentence, repeated it, and said, ‘Oh, I shall lose my train .
Expostulates with those who try to lead him to bed; says he will lose the train, that all things are packed up, and that he must start immediately.
Resists when being undressed, saying continually that he will lose the train.
Tries to put on his trousers and fasten and fasten his necktie.
I imagined I had to go off by a railway train, which started at ten in the morning, and that the hour was approaching, whilst I had nothing ready for the journey; and I believed that I wished to dress and to pack my things, but was thwarted and prevented by the people about me.
At length I was persuaded that it was too late to catch the train, and agreed to sat till evening.
Insisted repeatedly that her blood did not circulate, and that her feet must be put into warm water or she should die.
Talked confusedly and almost unintelligible nonsense, on waking in morning.
Agitation and delirium, worse at night.
Violent delirium and restlessness (after four and a half hours).
Delirious and a little drowsy.
Delirium followed by stupor.
Loud cries without any pains.
Sadness.
Mentally either very sad, depressed in constant anxiety and restlessness, fearful of misfortune, or angry and inclined to be alone, seldom lively.
Apprehensiveness followed his internal restlessness, and soon amounted to great anxiety.
Not quarrelsome or ill-tempered, but attempts to reason.
Very sensitive.
Constantly fretful.
I then became sensible that I was lifted into bed, and ordered on no account to rise, which I thought a most unreasonable restraint; especially as I was tormented with irritation in the bladder, and almost incessant desire to pass urine, which was in very small quantity.
Was generally restless and unmanageable, refusing to answer, to swallow, or to be examined; appeared profoundly intoxicated (after one hour).
Evidently unconscious and very irritable, striking his mother when she took him from the nurse (after one hour).
Incoherent quarreling (after eight hours).
Morose, quarrelsome the whole day, everything went wrong; trifles which usually passed unheeded irritated him to anger.
Desire to scold and quarrel.
INTELLECT: Upon making vigorous efforts to arouse him, he also exhibited some signs of consciousness.
When he closes his eyes the mind becomes confused and he sees all sorts of spectres (after thirteen hours).
Mind confused; would commence a sentence, and forget what she wished to say.
Feel as though awakened from a dream (second day).
Appears dull and stupid (after ten hours).
Has only vague ideas of anything she said, or of what transpired that evening.
When left to himself he did not appear to drop off into coma as do those who have taken opium, but would occasionally open his eyes with a vacant, amaurotic expression, and turn his head from side to side.
At first, a slowness of intelligence; ideas and replies are imperfect and indifferent.
Dull and stupid all the afternoon (after six hours).
Cannot be made to understand where he is, that he is ill, or that he must keep quiet.
First, indolence of mind, then vertigo, and a condition of commencing intoxication.
Feels dull and not inclined to move about or to converse (after one hour).
Indisposition for mental labor.
No desire for his ordinary mental labor.
Prover was dull and disinclined to study for several days.
For several days a difficulty of fixing upon anything for more than a few minutes at a time. The prover was absent-minded at intervals for several days, and found difficulty in fixing his mind upon any subject for more than a few minutes at a time.
Loss of memory (after eight hours).
His memory is wrong, inasmuch as he thinks that what really happened from the eleventh to the twelfth, took place in the night from the tenth to the eleventh (after sixth day).
Am absent-minded and forgetful; when conversing often partly finishing a sentence; was often obliged to stop and inquire what I had been saying (second day).
He recognizes, momentarily, members of the family; apparently notices when the door opens or one is busy about him but, when spoken to, often turns his head to the wrong side.
Unconscious, with incoherent speaking at intervals.
Comatose.
Head, face, and ears
Head.
Eyes.
VISION: Dimness of sight (after a quarter of an hour).
Dimness of vision (after eleven hours).
Dimness of vision, and bright circles of a golden color dancing before the eyes.
His difficulty in seeing small objects which were near him (the pupils were still dilated was now the most prominent feature remaining of his illness (after twenty-four hours).
Only a circular line of iris visible; was nearly blind; a thick cloud obstructed vision, and images were confused, with a reddish tinge (after one hour).
Can see but little; pupils considerable dilated, but contract readily under the influence of light (after three hours).
Objects appear at first enveloped in a white vapor; the contours are no longer distinct; if the dose is increased, almost complete blindness may ensue.
Disturbance of vision; objects seem enveloped in a cloud (the obscuration increases with the dose); even complete blindness ensues, but disappears in a day or two after ceasing the medicine.
Vision obscured; pupils dilated; eyeballs injected; she seems to see nothing about her.
Could see nothing (first day).
After looking at objects a few minutes, they become indistinct and fade from view (after two hours).
While reading a book, the letters gradually grew indistinct, and seemed wavering before the eyes.
Can see to read a little, but after a few words the letters grow indistinct, and am obliged to close the eyes to rest them (second day).
While talking with persons, then suddenly vanish (second day).
Eyes intolerant to light (second day).
The eye is sensitive to the light held in front of it, which, however, does not affect the dilatation of the pupil.
It is impossible to cause color-confusion by the use of the Atropine, but partial color-blindness may be induced by either the internal or external use of it.
The impressions made by color are altered by Atropine as regards strength exactly as they are by the different degrees of solar light on different days.
On several occasions through the night she had vision of great numbers of white flies on the door, which was white, and requested that they be brushed off.
They were not in motion, and were rather smaller than the common housefly.
This perversion of sight continued until noon of the following day, on closing the eyes. The medicine produced temporary bright spots and stars before the eyes, and a brilliant glow around the letters, which frightened him greatly.
Bright flashes before the eyes, immediately on closing them (first night).
On one occasion my patient was much annoyed by the appearance of a large black bag, with veritable legs, a few inches below a black doorknob.
On the following morning, imagining she saw a worm, a thousand-legged worm, on her carpet, she sprang out of bed, and was found trying to find it; failing in this, she would look in another place and see it again.
This illusion kept her busy some time, before fully satisfied of the fallacy.
The color of the worm was brown, the predominating color of the carpet.
Illusions of sight; during the increasing dimness of vision, manifold pictures of gigantic figures, whirls, double images; enlarged appearance of all objects; laughable or frightful appearances of all kinds.
Objects round or oval seem elongated; for example, the human figure was distorted so that the vertical diameter of the face seemed equal to the rest of the body; especially prominent were the nose and chin, which seemed of considerable length, and their margins enveloped in a mist; these appearances lasted some hours, for as I woke at half-past three, these images still floated clearly before the eyes; the pupils (on the next day) were very large and sluggish. First noticed diplopia (after five hours).
The next day these appearances were verified, though in a less degree; all objects seemed really elongated, especially the ears looked like Midas ears, and seemed to overtop the head; a round rubber ball looked egg shaped; the table looked oval rather than round (lasted till 10 A.M).
Vision much impaired; the figures on the carpet, which were large, appeared to be constantly and successively rising up to her face (perpendicular diplopia, the apparent object below the real one) As late as a week she still experienced a sense of giddiness, and the figures on the carpet would at times appear to her double.
Quick rotation and duplication of objects.
During the evening the eyes of the lady attendant seemed to her very large, and she could not avoid looking at them.
Upon looking at a newspaper the letters seem to expand and contract with each pulsation of the heart; can read but little (second day).
In attempting to walk, would reel and stagger, catch at objects which appeared to me in close proximity, but which in reality were far from my reach; would often stumble over objects which to me seemed to be many feet away (first day).
Cannot estimate distances correctly; when asked to put his hand upon an object within his reach, he either reaches too far or not far enough (after seven hours).
Entire loss of power to compare objects with the eye and determine their respective distances (first day).
Ears.
Throughout the succeeding night the hearing and sight were morbidly sensitive.
At night, when the eyes were closed, though not sound asleep, he heard every noise and every voice in the room and yard. Exquisite sensibility of hearing, and frequent illusions of this sense also.
His attention cannot be attracted without speaking loudly to him.
Perceptions of noise, thinking sounds as of bells, etc.
Some roaring in ears. Illusions of hearing, ringing, roaring, etc.
Nose.
Mucous membrane of the nose dry (after one hour).
Dryness of the mucous membrane of the nose and eye.
The dryness (of the throat) very often extends to the mucous membrane of the lower passage of the nares.
He sneezed and rubbed his nose frequently.
Face.
Expression of mania.
Looks and acts as if he had been on a spree (after seven hours).
Pale, slightly sweating face.
Flushing of the face.
Face flushed (after one hour).
Flushed face; burning in the face (after a quarter of an hour).
Eyes.
VISION: Dimness of sight (after a quarter of an hour).
Dimness of vision (after eleven hours).
Dimness of vision, and bright circles of a golden color dancing before the eyes.
His difficulty in seeing small objects which were near him (the pupils were still dilated was now the most prominent feature remaining of his illness (after twenty-four hours).
Only a circular line of iris visible; was nearly blind; a thick cloud obstructed vision, and images were confused, with a reddish tinge (after one hour).
Can see but little; pupils considerable dilated, but contract readily under the influence of light (after three hours).
Objects appear at first enveloped in a white vapor; the contours are no longer distinct; if the dose is increased, almost complete blindness may ensue.
Disturbance of vision; objects seem enveloped in a cloud (the obscuration increases with the dose); even complete blindness ensues, but disappears in a day or two after ceasing the medicine.
Vision obscured; pupils dilated; eyeballs injected; she seems to see nothing about her.
Could see nothing (first day).
After looking at objects a few minutes, they become indistinct and fade from view (after two hours).
While reading a book, the letters gradually grew indistinct, and seemed wavering before the eyes.
Can see to read a little, but after a few words the letters grow indistinct, and am obliged to close the eyes to rest them (second day).
While talking with persons, then suddenly vanish (second day).
Eyes intolerant to light (second day).
The eye is sensitive to the light held in front of it, which, however, does not affect the dilatation of the pupil.
It is impossible to cause color-confusion by the use of the Atropine, but partial color-blindness may be induced by either the internal or external use of it.
The impressions made by color are altered by Atropine as regards strength exactly as they are by the different degrees of solar light on different days.
On several occasions through the night she had vision of great numbers of white flies on the door, which was white, and requested that they be brushed off.
They were not in motion, and were rather smaller than the common housefly.
This perversion of sight continued until noon of the following day, on closing the eyes. The medicine produced temporary bright spots and stars before the eyes, and a brilliant glow around the letters, which frightened him greatly.
Bright flashes before the eyes, immediately on closing them (first night).
On one occasion my patient was much annoyed by the appearance of a large black bag, with veritable legs, a few inches below a black doorknob.
On the following morning, imagining she saw a worm, a thousand-legged worm, on her carpet, she sprang out of bed, and was found trying to find it; failing in this, she would look in another place and see it again.
This illusion kept her busy some time, before fully satisfied of the fallacy.
The color of the worm was brown, the predominating color of the carpet.
Illusions of sight; during the increasing dimness of vision, manifold pictures of gigantic figures, whirls, double images; enlarged appearance of all objects; laughable or frightful appearances of all kinds.
Objects round or oval seem elongated; for example, the human figure was distorted so that the vertical diameter of the face seemed equal to the rest of the body; especially prominent were the nose and chin, which seemed of considerable length, and their margins enveloped in a mist; these appearances lasted some hours, for as I woke at half-past three, these images still floated clearly before the eyes; the pupils (on the next day) were very large and sluggish. First noticed diplopia (after five hours).
The next day these appearances were verified, though in a less degree; all objects seemed really elongated, especially the ears looked like Midas ears, and seemed to overtop the head; a round rubber ball looked egg shaped; the table looked oval rather than round (lasted till 10 A.M).
Vision much impaired; the figures on the carpet, which were large, appeared to be constantly and successively rising up to her face (perpendicular diplopia, the apparent object below the real one) As late as a week she still experienced a sense of giddiness, and the figures on the carpet would at times appear to her double.
Quick rotation and duplication of objects.
During the evening the eyes of the lady attendant seemed to her very large, and she could not avoid looking at them.
Upon looking at a newspaper the letters seem to expand and contract with each pulsation of the heart; can read but little (second day).
In attempting to walk, would reel and stagger, catch at objects which appeared to me in close proximity, but which in reality were far from my reach; would often stumble over objects which to me seemed to be many feet away (first day).
Cannot estimate distances correctly; when asked to put his hand upon an object within his reach, he either reaches too far or not far enough (after seven hours).
Entire loss of power to compare objects with the eye and determine their respective distances (first day).
Ears.
Throughout the succeeding night the hearing and sight were morbidly sensitive.
At night, when the eyes were closed, though not sound asleep, he heard every noise and every voice in the room and yard. Exquisite sensibility of hearing, and frequent illusions of this sense also.
His attention cannot be attracted without speaking loudly to him.
Perceptions of noise, thinking sounds as of bells, etc.
Some roaring in ears. Illusions of hearing, ringing, roaring, etc.
Nose.
Mucous membrane of the nose dry (after one hour).
Dryness of the mucous membrane of the nose and eye.
The dryness (of the throat) very often extends to the mucous membrane of the lower passage of the nares.
He sneezed and rubbed his nose frequently.
Face.
Expression of mania.
Looks and acts as if he had been on a spree (after seven hours).
Pale, slightly sweating face.
Flushing of the face.
Face flushed (after one hour).
Flushed face; burning in the face (after a quarter of an hour).
Nervous system
CONFUSION AND VERTIGO: Head feels dull and unpleasant (after eleven hours).
Dull sensation in the head, with feeling as if his hair had become matted into a thick felt (first day).
Head very much confused; could be held up with difficulty.
Head confused, as after a disturbed night; relieved on going into the open air (morning, second day).
Dizzy confusion of the head, evenings, alternating with vivid phantasies; great fatigue of the whole body, and at times ringing in the ears.
Some vertigo (after one hour).
Some vertigo (after three hours).
Considerable vertigo (after seven hours).
Vertigo, in consequence of which I was obliged to lie down.
Vertigo at intervals, lasting but a moment at a time (after one hour).
Vertigo caused by turning the head quickly (after one hour).
Considerable vertigo, particularly upon turning the head suddenly (after half an hour).
Vertigo and confusion of the head, on waking, which increased on rising; vertigo so that he came near falling.
Vertigo on rising in the morning, so that it became dark before his eyes.
Has had slight vertigo at intervals during the forenoon (second day).
Slight vertigo and pressure in the temples with little or no pain (after a quarter of an hour).
Awoke very dizzy; cannot walk across the floor, but staggers towards objects for support (after three hours).
Giddiness.
Giddiness, heaviness, drowsiness, or actual sleep, with great tendency to dreamy delirium, and, in women, slight occasional startings (from 1/48 grain).
Awoke still feeling quite dizzy (second day).
Continued giddy, but walked steadily, though slowly and cautiously.
Dizziness upon moving the head suddenly (after eleven hours).
Dizziness upon moving the head quickly (second day).
Dizziness when attempting to walk (after two hours).
PAINS: Head hot (after four hours).
Head very hot.
Head hot (after ten minutes).
Head feels hot (after one hour).
Head and face much flushed and hot; pulse full, bounding, and irregular.
Head subjectively warm, but not painful; cold applications are grateful (second day).
Head feels full and uncomfortable (after two hours).
Feeling as if the head was screwed up; walking caused the most severe sticking pains; relieved toward 11 p.m, and disappeared by evening.
Dull pain in the head continues, with dizziness upon moving suddenly (third day).
Sticking pains in the base of the skull, and especially over the eyes, on every motion, and especially on stepping.
Sensation of fullness in the anterior part of the brain (after one hour).
Slight pain in the antero-superior cerebral region, coming on shortly after taking the drug, continuing through the night and next day.
Headache commencing in the middle of the forehead (fifteen minutes).
Fullness in the forehead, and head hot, but at no time any throbbing of the carotids or arteries of the head.
Slight fullness in the front part of the head, and dilation of the pupils.
Dull pain in the forehead, with dizziness on moving suddenly.
Pressive pain in forehead.
Fine, drawing, very sensitive stitches across the forehead and temples; recurred every four to ten minutes, and lasted several seconds or a minute. Slight pain in the temples (after half an hour).
Very slight pain in the temples and eyes (after twelve hours).
Fullness of temples and also of forehead, with very slight pain can scarcely walk, am so dizzy.
A feeling of fullness and pressure at the temples.
Slight pressure in the temples (after one hour).
Feeling in the head as though the temples were being pressed from without; pressure worse on the right side (after one hour).
Dull pain in the temples, coming on at intervals of perhaps a quarter of an hour, and lasting a few minutes.
This pain is not severe, but seems like a deep heavy pressure; at other times it is a steady tension in the anterior cerebral region, as if the brain was being pressed outward in all directions (first day).
Has a dull bruised feeling in the temples (after nine hours).
Very sensitive sticking in the left temporal region on waking in the morning; it extended to behind the ear, and scarcely permitted him to open his left eye; disappeared after moving about in the open air.
Throbbing in the temporal regions (after ten minutes).
Feeling of pressure under the parietal bones.
Dull sensation in the head, with feeling as if his hair had become matted into a thick felt (first day).
Head very much confused; could be held up with difficulty.
Head confused, as after a disturbed night; relieved on going into the open air (morning, second day).
Dizzy confusion of the head, evenings, alternating with vivid phantasies; great fatigue of the whole body, and at times ringing in the ears.
Some vertigo (after one hour).
Some vertigo (after three hours).
Considerable vertigo (after seven hours).
Vertigo, in consequence of which I was obliged to lie down.
Vertigo at intervals, lasting but a moment at a time (after one hour).
Vertigo caused by turning the head quickly (after one hour).
Considerable vertigo, particularly upon turning the head suddenly (after half an hour).
Vertigo and confusion of the head, on waking, which increased on rising; vertigo so that he came near falling.
Vertigo on rising in the morning, so that it became dark before his eyes.
Has had slight vertigo at intervals during the forenoon (second day).
Slight vertigo and pressure in the temples with little or no pain (after a quarter of an hour).
Awoke very dizzy; cannot walk across the floor, but staggers towards objects for support (after three hours).
Giddiness.
Giddiness, heaviness, drowsiness, or actual sleep, with great tendency to dreamy delirium, and, in women, slight occasional startings (from 1/48 grain).
Awoke still feeling quite dizzy (second day).
Continued giddy, but walked steadily, though slowly and cautiously.
Dizziness upon moving the head suddenly (after eleven hours).
Dizziness upon moving the head quickly (second day).
Dizziness when attempting to walk (after two hours).
PAINS: Head hot (after four hours).
Head very hot.
Head hot (after ten minutes).
Head feels hot (after one hour).
Head and face much flushed and hot; pulse full, bounding, and irregular.
Head subjectively warm, but not painful; cold applications are grateful (second day).
Head feels full and uncomfortable (after two hours).
Feeling as if the head was screwed up; walking caused the most severe sticking pains; relieved toward 11 p.m, and disappeared by evening.
Dull pain in the head continues, with dizziness upon moving suddenly (third day).
Sticking pains in the base of the skull, and especially over the eyes, on every motion, and especially on stepping.
Sensation of fullness in the anterior part of the brain (after one hour).
Slight pain in the antero-superior cerebral region, coming on shortly after taking the drug, continuing through the night and next day.
Headache commencing in the middle of the forehead (fifteen minutes).
Fullness in the forehead, and head hot, but at no time any throbbing of the carotids or arteries of the head.
Slight fullness in the front part of the head, and dilation of the pupils.
Dull pain in the forehead, with dizziness on moving suddenly.
Pressive pain in forehead.
Fine, drawing, very sensitive stitches across the forehead and temples; recurred every four to ten minutes, and lasted several seconds or a minute. Slight pain in the temples (after half an hour).
Very slight pain in the temples and eyes (after twelve hours).
Fullness of temples and also of forehead, with very slight pain can scarcely walk, am so dizzy.
A feeling of fullness and pressure at the temples.
Slight pressure in the temples (after one hour).
Feeling in the head as though the temples were being pressed from without; pressure worse on the right side (after one hour).
Dull pain in the temples, coming on at intervals of perhaps a quarter of an hour, and lasting a few minutes.
This pain is not severe, but seems like a deep heavy pressure; at other times it is a steady tension in the anterior cerebral region, as if the brain was being pressed outward in all directions (first day).
Has a dull bruised feeling in the temples (after nine hours).
Very sensitive sticking in the left temporal region on waking in the morning; it extended to behind the ear, and scarcely permitted him to open his left eye; disappeared after moving about in the open air.
Throbbing in the temporal regions (after ten minutes).
Feeling of pressure under the parietal bones.
Common symptoms
IN GENERAL: Strange appearance of the eyes, as though projected from their sockets (after one and a half hours).
Eyes appear fixed and glassy (first day).
Eyes look glassy and congested (after one hour).
Glittering, excited eyes.
Eyes restless (after one hour).
Eyes move restlessly hither and thither (ordinarily, his look is not steady).
Simple inflammatory swelling of the mucous membrane, with muco-purulent secretion, often accompanied by swelling of the lachrymal sac, occasionally with less swelling, but more marked hyperaemia and flow of tears.
Eyes considerably congested, but the pupils have scarcely commenced to dilate (after one hour). eyes feel wearied (second day) сonsiderable pain and lachrymation.
Slight pain in the eyes continued for about two hours, accompanied part of the time by an unpleasant sensation of fullness and pressure in the anterior part of the head, making me restless and uneasy.
Eyes feel swollen, and pain in the eyes and temples slightly increased with each pulsation of the heart (after twelve hours).
Dull pain in the eyes and head.
Dull pain in the eyes, and slight pain in the temples (after one hour).
Deep seated dull pain in the back part of the eye (after ten minutes).
Eyes and lids feel sore to the touch 9 (after nine hours).
BROW, LIDS, ETC. Sharp pain under the right eye, with slight pain in the temples (after four hours).
Neuralgic pains, commencing under the left orbit, and running back to the ear, lasting perhaps ten minutes at a time, and then disappearing for fifteen or twenty; these have been noticed for several hours (second day).
Redness and excoriation of the skin of the eyelids.
Eyelids swollen (after one hour).
About 9 eyelids felt heavy and difficult to keep open; yet she had no inclination to sleep.
Dull, heavy, aching pain in the eyelids, not severe (second day).
Eyelids feel sore are red and congested (second day).
I have myself once or twice experienced slight congestion of the entire conjunctiva, with dryness of the membrane and dull aching pain in the eyeball, after the use of a very weak solution of Atropia.
On one occasion this condition followed the instillation of 12 drops of a solution of 1 part of Sulphate of Atropia in 400,000 parts of water.
Slight injection of the conjunctival membrane. сonjunctivae vividly injected (after one hour).
Acute erysipelatous inflammation and swelling of the conjunctiva and eyelids.
Atropine conjunctivitis.
Severe pain in the left eyeball (after nine hours).
Slight pain in the eyes continued; it is as if the eyeballs were pressed from without in every direction (after twelve hours).
Pupils not unusually dilated, but perfectly immovable.
Pupils dilated.
Pupils somewhat dilated.
Pupils very much dilated; spectral illusions continue (second day).
Both pupils dilated, but not ad maximum.
Excessive dilatation of pupils (first day).
Complete mydriasis.
Pupils are still dilated; can see to read quite distinctly for a few minutes, after which the letters, words, and lines run together and become indistinct (second day).
Dilatation and immobility of the pupil.
Pupils slightly dilated; conjunctiva not injected.
Pupils still dilated, with diplopia (second day).
Pupils considerably dilated; vertigo increasing (after one hour).
Eyes appear fixed and glassy (first day).
Eyes look glassy and congested (after one hour).
Glittering, excited eyes.
Eyes restless (after one hour).
Eyes move restlessly hither and thither (ordinarily, his look is not steady).
Simple inflammatory swelling of the mucous membrane, with muco-purulent secretion, often accompanied by swelling of the lachrymal sac, occasionally with less swelling, but more marked hyperaemia and flow of tears.
Eyes considerably congested, but the pupils have scarcely commenced to dilate (after one hour). eyes feel wearied (second day) сonsiderable pain and lachrymation.
Slight pain in the eyes continued for about two hours, accompanied part of the time by an unpleasant sensation of fullness and pressure in the anterior part of the head, making me restless and uneasy.
Eyes feel swollen, and pain in the eyes and temples slightly increased with each pulsation of the heart (after twelve hours).
Dull pain in the eyes and head.
Dull pain in the eyes, and slight pain in the temples (after one hour).
Deep seated dull pain in the back part of the eye (after ten minutes).
Eyes and lids feel sore to the touch 9 (after nine hours).
BROW, LIDS, ETC. Sharp pain under the right eye, with slight pain in the temples (after four hours).
Neuralgic pains, commencing under the left orbit, and running back to the ear, lasting perhaps ten minutes at a time, and then disappearing for fifteen or twenty; these have been noticed for several hours (second day).
Redness and excoriation of the skin of the eyelids.
Eyelids swollen (after one hour).
About 9 eyelids felt heavy and difficult to keep open; yet she had no inclination to sleep.
Dull, heavy, aching pain in the eyelids, not severe (second day).
Eyelids feel sore are red and congested (second day).
I have myself once or twice experienced slight congestion of the entire conjunctiva, with dryness of the membrane and dull aching pain in the eyeball, after the use of a very weak solution of Atropia.
On one occasion this condition followed the instillation of 12 drops of a solution of 1 part of Sulphate of Atropia in 400,000 parts of water.
Slight injection of the conjunctival membrane. сonjunctivae vividly injected (after one hour).
Acute erysipelatous inflammation and swelling of the conjunctiva and eyelids.
Atropine conjunctivitis.
Severe pain in the left eyeball (after nine hours).
Slight pain in the eyes continued; it is as if the eyeballs were pressed from without in every direction (after twelve hours).
Pupils not unusually dilated, but perfectly immovable.
Pupils dilated.
Pupils somewhat dilated.
Pupils very much dilated; spectral illusions continue (second day).
Both pupils dilated, but not ad maximum.
Excessive dilatation of pupils (first day).
Complete mydriasis.
Pupils are still dilated; can see to read quite distinctly for a few minutes, after which the letters, words, and lines run together and become indistinct (second day).
Dilatation and immobility of the pupil.
Pupils slightly dilated; conjunctiva not injected.
Pupils still dilated, with diplopia (second day).
Pupils considerably dilated; vertigo increasing (after one hour).
Analogs by action
- 29% — Iodoformum
- 28% 1-13.8€ Morphinum aceticum
- 28% 1-13.8€ Jaborandi
- 27% 1-13.8€ Robinia pseudacacia
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Included in the composition
- 4.8€ Meditonsin
- 4.8-6.2€ Spascupreel (Сигнал НЦ ФГУП )
- 5.8-7.5€ Tonsilotren (3 firms)
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- — Atropinum compositum
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