Compatibility «Concor AM» and «Ko-Vamloset»

• Interactions Concor AM with Ko-Vamloset

  • Dangerous interactions
    • ⓘ Calcium channel blockers(C08) + Drugs that cause hypokalemia; Glucocorticosteroids (C03A, A01AB04,J02AA01,H02,D07 => Increases the likelihood of ventricular tachycardia and ventricular fibrillation. (A dangerous combination, it is necessary to eliminate hypokalemia before use).
    • ⓘ Simultaneous administration of dihydropyridine calcium antagonists, especially in patients with latent heart failure, increases the risk of hypotension and decompensation of cardiac activity.
  • Negative interactions
    • ⓘ Amlodipine can be safely used for the treatment of hypertension together with thiazide diuretics, alpha-blockers, beta-blockers or ACE inhibitors.
    • ⓘ During monotherapy with amlodipine, there is no clinically significant interaction with thiazide diuretics, beta-blockers, ACE inhibitors, long-acting nitrates, nitroglycerin for sublingual use, digoxin, warfarin, atorvastatin, sildenafil, antacid drugs (magnesium hydroxide, aluminum hydroxide gel, simeticone), cimetidine, NSAIDs, antibiotics and hypoglycemic agents for ingestion.
    • ⓘ Antihypertensive drugs.
    • ⓘ Concomitant use of thiazide diuretics (including hydrochlorothiazide), with beta‑blockers or diazoxide may increase the risk of hyperglycemia.
    • ⓘ Drugs: Concor AM and Ko-Vamloset there is common active substance : Amlodipine. Pay attention to the dosage..
    • ⓘ Other antihypertensive and antianginal drugs.
    • ⓘ Amlodipine can be safely used to treat hypertension together with thiazide diuretics, beta-blockers or ACE inhibitors.
    • ⓘ Blockers of 'slow' calcium channels (BMCC) such as verapamil and to a lesser extent diltiazem, when used simultaneously with bisoprolol, can lead to a decrease in myocardial contractility and impaired AV conduction.
    • ⓘ BMCC derivatives of dihydropyridine (for example, nifedipine, felodipine, amlodipine), when used concomitantly with bisoprolol, may increase the risk of arterial hypotension.
  • No interactions
    • ⓘ Pharmacokinetic studies have not revealed interactions of bisoprolol with thiazide diuretics such as hydrochlorothiazide and cimetidine.
    • ⓘ In patients with stable angina pectoris, amlodipine can be used in combination with other antianginal agents, for example, with prolonged or short-acting nitrates beta-blockers.
  • Positive interactions
    • ⓘ Antihypertensive drugs, as well as other drugs with a possible antihypertensive effect (for example, tricyclic antidepressants, barbiturates, phenothiazines), can enhance the antihypertensive effect of bisoprolol.
    • ⓘ It is possible to enhance the antianginal and hypotensive effects of BMCC when combined with thiazide and loop diuretics, ACE inhibitors, beta-blockers and nitrates, as well as to enhance their hypotensive effect when combined with alpha₁-blockers, neuroleptics.
    • ⓘ It is possible to enhance the antianginal and antihypertensive effects of BMCC when combined with thiazide and loop diuretics, ACE inhibitors, beta-blockers and nitrates.
  • Unclear interactions
    • ⓘ Bisoprolol + Hydrochlorothiazide analgin and citramon are used together in 7 preparations.
    • ⓘ Beta-blockers, diazoxide.
    • ⓘ Amlodipine + Amlodipine+Valsartan+Hydrochlorothiazide analgin and citramon are used together in Co-Exforge, Тритензин, Ko-Vamloset.
    • ⓘ Amlodipine + Valsartan analgin and citramon are used together in 16 preparations.
    • ⓘ Amlodipine + Hydrochlorothiazide analgin and citramon are used together in Co-Exforge, Тритензин, Ko-Vamloset.
    • ⓘ Amlodipine + Bisoprolol+Amlodipine analgin and citramon are used together in Amlodipine+Bisoprolol, Concor AM.
    • ⓘ Amlodipine + Bisoprolol analgin and citramon are used together in 5 preparations.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,027,037 possible combinations of drugs and their components were found 412,563 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-01-01

Category - medicine