Compatibility «Aevit in capsules» and «Neuromultivit»

• Interactions Aevit in capsules with Neuromultivit

  • Dangerous interactions
    • ⓘ Simultaneous administration of other multivitamin complexes containing vitamin E is not recommended in order to avoid overdose.
    • ⓘ Drinks containing sulfites (e.g. wine) enhance thiamine degradation.
    • ⓘ The drug Magne B6 should be prescribed at least 3 hours after ingestion of tetracycline (td; magnesium preparations reduce the absorption of tetracyclines).
    • ⓘ Quinolones should be prescribed at least 2 hours before or 6 hours after taking Magne B6 in order to avoid impaired absorption of quinolones.
    • ⓘ Thiamine hydrochloride and benzylpenicillin or streptomycin (destruction of antibiotics), thiamine and nicotinic acid (destruction of thiamine) should not be mixed in one syringe.
    • ⓘ Thiamine hydrochloride solution should not be mixed with solutions containing sulfites, etc.; it completely disintegrates in them.
    • ⓘ Pharmaceutically (in one syringe) incompatible with solutions of vitamins B₁ and B₆ (cobalt ion contributes to the destruction of other vitamins).
    • ⓘ Increases the likelihood of allergic reactions caused by vitamin B₁.
  • Negative interactions
    • ⓘ When used concomitantly with levodopa, pyridoxine may reduce the antiparkinsonian effect of levodopa.
    • ⓘ Simultaneous use of pyridoxine antagonists (e.g. isoniazid, hydralazine, penicillamine or cycloserine) may increase the need for pyridoxine.
    • ⓘ Thiamine is inactivated by fluorouracil.
    • ⓘ Fluorouracil competitively inhibits the phosphorylation of thiamine to thiamine pyrophosphate.
    • ⓘ by increasing the excretion of thiamine with prolonged use, which leads to a decrease in the content of thiamine in the blood.
    • ⓘ Taking alcohol and black tea leads to a decrease in thiamine absorption.
    • ⓘ With simultaneous use of Magne B6 and levodopa at a dose of 5 mg or more, the effects of levodopa decrease.
    • ⓘ Therefore, in patients taking levodopa, Magne B6 should be prescribed simultaneously with peripheral dopadecarboxylase inhibitors.
    • ⓘ Simultaneous use of drugs containing phosphates, calcium salts or iron ions is not recommended, since such drugs reduce the absorption of magnesium in the intestine.
    • ⓘ Pyridoxine inhibits the conversion of thiamine into thiamine pyrophosphate, increases allergization.
    • ⓘ do not mix (in one syringe) with penicillin, streptomycin, nicotinic acid.
    • ⓘ Thiamine hydrochloride reduces the pharmacological activity of salts of suxamethonium, phentolamine, propranolol, sympatholytics (reserpine), hypnotics (reduces hypnotic and hypotensive effects).
    • ⓘ Thiamine (vitamin B1) (A11DA01) + Cyanocobalamin (vitamin B12) => Increased allergic reaction.
    • ⓘ When taking oral contraceptives, metformin and antipsychotic drugs (such as olanzapine and risperidone), the concentration of vitamin B₁₂ in the blood serum may be reduced.
    • ⓘ Chloramphenicol can weaken the effect of vitamin B₁₂ in anemia.
    • ⓘ Prolonged exposure to nitric oxide can cause functional vitamin B deficiency₁₂ and possible serious neurological side effects even with normal vitamin B values₁₂.
  • No interactions
    • ⓘ

      Interactions from the instructions of the drug with this active substance (Magne B6)

      .
    • ⓘ

      Interactions from the instructions of the drug with this active substance (Thiamine-Vial)

      .
    • ⓘ

      Interactions from the instructions of the drug with this active substance (B12 Ankermann)

      .
  • Positive interactions
    • ⓘ enhances the allergenic effect of thiamine.
  • Unclear interactions
    • ⓘ Pyridoxine + Vitamin E analgin and citramon are used together in 77 preparations.
    • ⓘ Vitamin E + Thiamine analgin and citramon are used together in 89 preparations.
    • ⓘ Cyanocobalamin + Vitamin E analgin and citramon are used together in 84 preparations.
    • ⓘ Vitamin E + Multivitamins analgin and citramon are used together in 27 preparations.
    • ⓘ Antacids reduce the absorption of thiamine.
    • ⓘ Pyridoxine + Retinol analgin and citramon are used together in 64 preparations.
    • ⓘ With preparations containing phosphates, calcium salts or iron ions.
    • ⓘ Retinol + Thiamine analgin and citramon are used together in 71 preparations.
    • ⓘ Simultaneous parenteral administration of thiamine hydrochloride and pyridoxine (vitamin B₆) or cyanocobalamin (vitamin B₁₂) is not recommended.
    • ⓘ it makes it difficult to convert thiamine hydrochloride into a biologically active form.
    • ⓘ Thiamine hydrochloride is unstable in alkaline and neutral solutions; administration with carbonates, citrates, barbiturates, and copper preparations is not recommended.
    • ⓘ Retinol + Cyanocobalamin analgin and citramon are used together in 63 preparations.
    • ⓘ Absorption of vitamin B₁₂ may be impaired by the use of proton pump inhibitors (e.g. omeprazole), blockers of H₂-histamine receptors (e.g. cimetidine), colchicine, aminoglycosides (e.g. neomycin), aminosalicylic acid, antiepileptic drugs, salts potassium, methyldopa, as well as against the background of alcohol intake.
    • ⓘ Retinol + Multivitamins analgin and citramon are used together in 22 preparations.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
• Why do I need to
  • Avoid dangerous prescriptions for your patients.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,039,738 possible combinations of drugs and their components were found 412,575 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-05-28

Category - medicine