Compatibility «Indomethacin» and «Polydexa with phenylephrine»
Between «Indomethacin» and «Polydexa with phenylephrine» found 4 dangerous and 3 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Polydexa with phenylephrine |
✘Indomethacin Analogs | |
✘Polydexa with phenylephrine [Dexamethasone+Neomycin+Polymyxin B+Phenylephrine and more 4Dexamethasone, Neomycin, Polymyxin B, Phenylephrine] Analogs |
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Interactions Indomethacin with Polydexa with phenylephrine
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Dangerous interactions
Ethanol, colchicine, glucocorticoids and corticotropin increase the risk of gastrointestinal bleeding. Reduce the therapeutic and toxic effects of barbiturates, phenytoin, rifampicin (accelerate metabolism), somatotropin, antacids (reduce absorption), enhance - estrogen-containing oral contraceptives, the risk of arrhythmias and hypokalemia - cardiac glycosides and diuretics, the likelihood of edema and hypertension - sodium-containing drugs or supplements, severe hypokalemia, heart failure and osteoporosis - amphotericin In and carbonic anhydrase inhibitors, the risk of erosive ulcerative lesions and bleeding from the gastrointestinal tract - NSAIDs. Prolonged simultaneous use of NSAIDs and GCS should be avoided due to an increased risk of adverse events from the gastrointestinal tract and impaired water-electrolyte balance. Increases the toxicity of zidovudine (by inhibiting metabolism), in newborns increases the risk of developing toxic effects of aminoglycosides (td. -
Negative interactions
Reduces the effectiveness of uricosuric and hypotensive drugs (in pm beta-blockers); enhances the side effects of mineral and glucocorticoids, estrogens. In addition, NSAIDs can mask fever, pain, swelling and other signs and symptoms of infection. Glucocorticoids (H02AB) + Amidopyrine, acetylsalicylic acid, butadione, indomethacin and other nonsteroidal anti-inflammatory drugs => Development of edema, increased damaging effect on the mucous membrane of the gastrointestinal tract. -
Unclear interactions
Indomethacin. False negative dexamethasone test results have been reported in patients treated with indomethacin. НПВС.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
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Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,972,605 possible combinations of drugs and their components were found 412,508 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-04-11
Category - medicine