Description Source
Encyclopedia of Pure Materia Medica - TF AllenAdditional facts
Sodium salicylate, NaC7H6O3 plus H2O.
Preparation, Triturations or solutions.
The patient’s psychical condition was very striking, perfectly rational periods alternating with manifestations of insanity of a sombre character. This condition gradually disappeared in about eight days, the rational periods gradually becoming longer. The temperature had no influence on the psychical disturbances.
After her recovery, the patient remembered nothing that had happened during this entire period. In her rational intervals, she complained of severe headache, ringing in the ears, deafness, and impairment of vision for distant objects. For three or four days there were strabismus divergens and marked mydriasis; for four or five days there was hoarseness, but as a laryngoscopic examination could not be made, Doctor Peterson is unable to say whether it depended on laryngitis or on paralysis of the vocal cords.
The respiration was rapid (forty per minute), but inspiration was quite deep. The pulse varied independently of the temperature, being at one time between 120 and 130, and at another between 80 and 60. The salicylate of soda did not, in this case, exert a prompt influence on the temperature.
Circumscribed spots of vascular dilation, which changed their position from time to time, were observed on the face, neck, breast, and leg; these lasted for three days. A bed-sore rapidly formed on the sacrum, and was ascribed by Doctor Peterson to the vaso-motor disturbances. There was vomiting, but no gastric pains; no diarrhoea, but a very fetid smell to the faeces. The urine contained at least one-fifth per cent, of albumen, which gradually disappeared. There was no oedema of the legs. The treatment was symptomatic. вromide of potassium was administered. During the subsequent two weeks, traumatic erysipelas set in on two occasions, but was arrested by subcutaneous injections of Salicylic acid. After the last injection, symptoms of poisoning (redness of face, dilatation of pupils, frequent respiration, pulse 130, etc.), set in, although the dose was very small gramme, solution = 2 centigrammes. acid).
Preparation, Triturations or solutions.
The patient’s psychical condition was very striking, perfectly rational periods alternating with manifestations of insanity of a sombre character. This condition gradually disappeared in about eight days, the rational periods gradually becoming longer. The temperature had no influence on the psychical disturbances.
After her recovery, the patient remembered nothing that had happened during this entire period. In her rational intervals, she complained of severe headache, ringing in the ears, deafness, and impairment of vision for distant objects. For three or four days there were strabismus divergens and marked mydriasis; for four or five days there was hoarseness, but as a laryngoscopic examination could not be made, Doctor Peterson is unable to say whether it depended on laryngitis or on paralysis of the vocal cords.
The respiration was rapid (forty per minute), but inspiration was quite deep. The pulse varied independently of the temperature, being at one time between 120 and 130, and at another between 80 and 60. The salicylate of soda did not, in this case, exert a prompt influence on the temperature.
Circumscribed spots of vascular dilation, which changed their position from time to time, were observed on the face, neck, breast, and leg; these lasted for three days. A bed-sore rapidly formed on the sacrum, and was ascribed by Doctor Peterson to the vaso-motor disturbances. There was vomiting, but no gastric pains; no diarrhoea, but a very fetid smell to the faeces. The urine contained at least one-fifth per cent, of albumen, which gradually disappeared. There was no oedema of the legs. The treatment was symptomatic. вromide of potassium was administered. During the subsequent two weeks, traumatic erysipelas set in on two occasions, but was arrested by subcutaneous injections of Salicylic acid. After the last injection, symptoms of poisoning (redness of face, dilatation of pupils, frequent respiration, pulse 130, etc.), set in, although the dose was very small gramme, solution = 2 centigrammes. acid).
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Manufacturers (or distributors) of the drug
