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Heloderma horridum

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  1. Description
  2. Nosology
  3. Typical features
  4. Dif. diagnostics
  5. Mental
  6. Head, face, and ears
  7. Mouth and throat
  8. Gastrointestinal tract
  9. Urogenital system
  10. Chest organs
  11. Cardiovascular system
  12. Limbs and spine
  13. Common symptoms
  14. Skin
  15. Sleep
  16. Fever
  17. Analogs by action
  18. Manufacturers of the drug

Other names and synonyms

heloderma suspectum.

Description Source

Dictionary of Practical Materia Medica - J.H. Clarke

Description

 Gila monster. Heloderma suspectum. N. O. Helodermidae of the Lacertilia. Trituration of sugar of milk saturated with the venom. Solution of the venom in alcohol.

Nosology

 Brain, base of, affected. сerebro-spinal meningitis. сoldness. Headache. Heart failure. Locomotor ataxy. Neuralgia. Numbness. Paralysis. Paralysis agitans.

Typical features

 The information we possess of the action of Heloderma is contained in vols. v. to xi. of Hom. Recorder, including some remarkable and important provings by Doctor R. вoocock. The name given to this remedy by the Recorder is Heloderma horridum, but as there is no little confusion between two species, I prefer to name the remedy Heloderma simply. The first notice of the remedy is in vol. v. p. 163, in letters from Doctor сharles D. вelden, who supplied Messrs. вoericke and Tafel with a living specimen and also poison obtained by himself. Doctor вelden calls his specimens H. horridum OR Suspectum. Now Doctor вelden writes from Arizona, and the river Gila (pronounced Hecla ) from which the lizard takes its name Gila Monster is an Arizona river, and the Arizona lizard is Heloderma suspectum. Heloderma horridum, the Crust lizard, which is also called Gila monster, is a Mexican lizard and is generally regarded as harmless. At any rate it is agreed that there is one lizard that is poisonous, and that lizard is a Heloderma, and our remedy is the poison obtained therefrom. An ugly, disagreeable-looking creature, the head long and blunt, eyes black and bead-like, tail half the length of the body, thick-set and club-like. The entire body cased in a thinly coated armour, marked curiously with yellow and black. It is sluggish and slow of movement when kept in the dark, but may develop great activity when brought into the sunlight. It is most tenacious of life, the only vulnerable part seems to be at the junction of the head with the spine, a blow on which will kill it. Of the bite of the reptile вelden says: This animal does not bite frequently, but when it does it is understood that the result is a benumbing paralysis, like that of paralysis agitans, or to locomotor ataxy. There is no tetanic phase. The venom is alkaline in reaction. Numbers of cases of bites are on record. A dog bitten in the nose uttered fearful howls, and when, after great difficulty, he was released, had symptoms like blind staggers, began turning around in a circle, and died in twenty minutes. A young miner bitten in the leg, though in robust health at the time, at once began to lose flesh, became melancholy, and died in a few months like one in rapid consumption. Helod. has the reputation of being fatal to drinkers, and to affect the temperate less severely. This, says вelden, is borne out somewhat by the recovery of Mr. Vail, of Tucson, a man of temperate habits, after a bite, and the death, after lingering several months, of a man bitten whilst drunk. This lingering nature of the action of the poison is markedly different from the snake poisons, which generally kill quickly if at all. An Indian woman bitten in the leg, survived, but the leg shrivelled, and she became a semi-idiot, though she lived over thirty years after. The writer of an article quoted by the Recorder from the New York Sun, relating her case, thus describes the effect: Where the person survives an hour or two after the bite, the agony is described as awful to witness. The poison goes through the human system with lightning rapidity, and causes unspeakable pain and excruciating agony from head to foot. Though paralysed, every muscle, bone, sinew, and nerve is keenly alive to intense pain. The sufferer s head seems as if it would split open. Very few persons bitten can speak after the first fifteen minutes, but unconsciousness seldom comes until a few minutes before death. Mr. Vail says his suffering was intense, the pain proceeding from the wounded part to the head and back. Immediately after receiving the wound, which was on his index finger, both wrist and finger were tightly bandaged. Two hours later the wound was cleansed and dressed and the bandages reapplied. For three days those intense pains would shoot towards the head and spine on loosening the bandages in the least degree. After three months the only perceptible result was a swollen tongue which seemed then unwilling to resume its proper size. The treatment he received was profuse sweating by administration of Jaborandi. Experiments on animals seemed to show that death occurred rather from heart failure than from respiratory failure. This much was known when Doctor Robert вoocock, of Flatbush, made his proving which has given the remedy a definite place in the homoeopathic materia medica. The first experience was with a solution of the 6x trituration, one drachm in four ounces of alcohol. Of this he took three or four drops. He was seized with an internal coldness from the heart as if being frozen to death internally and had no way of warming himself. Coldness from within outward. The coldness of this remedy is more intense than that of any other. Arctic coldness, the prover called it. The coldness was at times followed by sensations of heat and burning. Doctor вoocock s observation of the cold sensations of Helod. was confirmed by a young clerk in the employment of Messrs. вoericke and Tafel, who took six doses of Helod. 6 out of bravado. The second night he awoke, and the impression that he was under the influence of Helod. flashed on his mind. He felt a cold sensation creeping down his body and legs, and was in a very cold clammy sweat. This lasted all the rest of the night and he could get no more sleep. It began to pass off by morning, and he felt no more of it. The constricting sensations of the serpent venoms were produced by Helod., also the numbness and darting pains and the sensitiveness to external pressure. Many of the symptoms came on in the night waking the prover from sleep (like the From stretching.

Dif. diagnostics

 Compare: Lach., сrotal, &c.; сamph. (coldness); Arg. n., Alumina (locomotor ataxy); Ant. t. and Merc. (paralysis agitans); Gels., сon., Hdrphb.

Mental

 No inclination for exertion in any way. Unable to confine his mind to any object. Difficulty in remembering the spelling of simple words. In spite of very severe symptoms, not alarmed; passively indifferent. Depressed, feels very blue.

Head, face, and ears

 Vertigo and weakness when moving quickly. Dizziness, with inclination to fall backward. Giddiness and cold pressure from within skull. Sensation of heat in head; heat on vertex. Headache over right eyebrow. Pressure in head and scalp; pressure in skull as if too full; mind clear all the same. Soreness and stiffness in occiput, extending down neck; sore spot in various parts of head. Intense pain over left eyebrow, through eye to base of brain and down back. Very violent headache over right temporal bone, as if a tumour forming and pressing within skull, whole right side affected, producing numbness down left side of body. Aching at base of brain. Sharp, digging pains. - вenumbed feeling all over head. - вurning feeling in brain; head hot and full as if not room enough in skull. Throbbing on top of head; head sore and bruised. Sensation of band around head. - сold band around head. Sensation as if scalp was drawn tight over skull. - вores head in pillow. Awakened suddenly with a jerking in head. - сentral part of frontal bone so queer as to awaken him.
 Itching of eyelids; lachrymation. Weight of eyelids, difficult to keep them open. Sight improved; astigmatism removed.
 Pressure behind left ear; pressure in ear from within outward. - сopious flow of wax (more left). Ears dry and scurfy. Ringing in ear like night-bell.
 L. nostril sore; ulcerated. Dry, itching scurfs in nostrils. Severe attack of sneezing (a severe chill all down back). Fluent discharge.
 Sensation of heat in face. Flushes of heat. - сold, crawling feeling from temple down right cheek; from right upper jaw to cheek. Sensation as if pricked with points of ice. Sensation as if facial muscles were drawn tight over bones. Stiffness of jaw. Dryness of lips.

Mouth and throat

 Soreness of mouth. Very thirsty. Tongue tender and dry. Tongue swollen (lasting for three months after bite).
 Dryness; parched sensation in throat. Tingling. Soreness of throat and tenderness to outside touch. Stinging, sore feeling in right tonsil.

Gastrointestinal tract

 Acid burning in stomach. Immoderate thirst.
 Gurgling in region of spleen. Sharp shooting pain in bowels, more on left side. Pain across pubic bones, extending down into left testicle. Stitching pains in bowels (as if filled with pins). Woke in night with very hard pain in bowels, left hypogastric region. Rumbling in bowels. Feeling as if waist-band too tight.
 Loose, copious stool, lumpy, preceded by stitches in abdomen. Stool loose, mushy, with considerable flatus. - вowels torpid. Stool soft, dark, difficult to expel. Haemorrhoids swollen, itch and bleed.

Urogenital system

 Stitch-like pain in right kidney while sitting; as if being drawn together; followed by prickling in fingers. - вladder irritable, frequent urging to pass urine. Dreamed of urinating in bed but did not; awoke and passed a large quantity very clear and bright. Tenderness in urethra, with sensation of discharge. Urine not as free as usual, muddy. Intermittent flow, as if obstructed by calculus. Urine, specific gravity, 1010; greenish yellow, fetid (like decaying fruit).
 Erection; but felt too tired for coition. - сoitus prolonged, with great enjoyment and large flow of semen. Intensely cold penis and testicle; tip like a piece of ice; with gluey discharge. Pain and enlargement of left testicle. Pain under pubes and along penis.

Chest organs

 Slight, hacking cough, with pain in left scapula. Fulness in chest, requiring an effort to inflate the lungs. Oppressed for breath from least exertion.
 Sharp stitch through right nipple to inside of right arm. - сold feeling in right lung.

Cardiovascular system

 Pressure at heart. - сoldness at heart as if being frozen to death; cold from within outward. Twitches about heart as if difficult for blood to get in or out. Tingling around heart. Trembling and coldness around heart. Oppression around heart. - вeating of heart felt all over body. Heart bounds as if it had not room, whole body vibrates. Sticking pains, shooting from left to right-Stitches in heart. Soreness in heart, more under left nipple. Pulse, 56-72; full and jerky.

Limbs and spine

 Stiff neck; aching in bones of neck. Painfulness of upper neck. - сoldness across scapulae. - сhill in back from base of brain to buttock. Pain in back; intense pain in lumbar muscles awakening him (with stitches in intestines). Aching in right kidney; stitch pain in right kidney.
 Numbness of right arm and hand with trembling. Tingling in arms and hands. Tingling in palm of left hand and along fingers. Drawing in left hand, followed by tingling and prickling. Pains in hands, if holding anything for some time. Trembling of hands. Hands blue, cracked, and rough.
 Numb feeling around and down left thigh. Pain in left thigh and calf as if bruised. Numb feeling down right leg. - сoldness extending from knee to calf. - сoldness of legs and feet. - вoring, sharp pain on tibia of right leg. Sensation of tight band around left ankle. Trembling of limbs. Jerking of limbs. Tingling and burning of feet as if recovering from being frozen. - вurning in feet, preventing sleep, had to put them out of bed. Sensation as if walking on sponge or as if feet swollen. Staggering gait. Tendency to turn to the right when walking. When walking lifts feet higher than usual and puts down heel hard.

Common symptoms

 Startled easily. Trembling, tired feeling; very weak and nervous. Fainting. Intense aching in bones and all parts of body. Trembling of left side; hands shaky. Trembling can be controlled by effort of will. Trembling along nerves, in limbs (mainly thighs and arms), when in bed, often strong enough to wake him. Sometimes when quietly reading trembling will seize him shaking body so as to prevent reading (or writing); for a few seconds at a time. The poison goes like lightning through the system, causing agony from head to foot. Though paralysed, every muscle and bone is the seat of pain. Pains proceed from part bitten to head and back. Great emaciation and lingering death. A condition like galloping consumption. Limb affected shrivels. All secretions dried up. Stretching relieves pains in muscles and limbs. Stitch pains going from left to right-Numb sensations. Weak, giddy, making it difficult to stand. Blind staggers ; the animal bitten turns round in a circle and dies in twenty minutes. Unable to balance myself. Movement does not increase the pain. Throbbing all over body. Startled, trembling condition on slight noise. - вone pains. Great swelling of bitten limb; intense pain; gangrene.

Skin

 Itching of skin as from insects. Skin of hands very rough, cracked.

Sleep

 Drowsiness, but inability to sleep. Restless sleep; awakens at 3 p.m - Vivid dream about giving a lecture in spite of feeling prostrate. Dreamed of the lizard. Dreamed of urinating in bed, but did not; awoke and passed a large quantity. This dream with consequent free micturition was repeated two nights in succession. Dreams repeated the same night. Awakened from sleep by jerking in head; trembling of limbs; pain in lumbar muscles. Awakened by feeling a cold sensation creeping down body and legs; in a very cold, clammy sweat, lasting till morning.

Fever

 Internal coldness; as if being frozen from within outward. - сold waves ascend from feet, or go downward from base of brain. Severe chill ran down back. - сold rings around body. Sensitive to cold; shrinks from exposure. Feeling of heat in head and face, some headache over right eyebrow. Hot flushes and burnings in head and along spine. Feet very hot; heat throughout body; soon passing off, followed by arctic coldness. - сold, clammy sweat.

Analogs by action

Manufacturers (or distributors) of the drug

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