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Chininum arsenicosum

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  1. Additional facts
  2. Nosology
  3. Mental
  4. Head, face, and ears
  5. Mouth and throat
  6. Appetite and food preferences
  7. Gastrointestinal tract
  8. Urogenital system
  9. Chest organs
  10. Cardiovascular system
  11. Limbs and spine
  12. Nervous system
  13. Sleep
  14. Common symptoms
  15. Fever
  16. Skin
  17. Patient type and constitution
  18. Dif. diagnostics
  19. Analogs by action
  20. Included in the composition
  21. Manufacturers of the drug

Description Source

Guiding Symptoms of Our Materia Medica - C. Hering

Additional facts

 Arseniate of Quinine. 2C20 H24 N2O2. As H3. 4H2O.
 Until proved by the Philadelphia сlinical Society, at the instigation of Doctor William H. вigler, who cured with it a case of scrofulous ophthalmia, the only proving we had was the short one by Doctor Muhr, contained in Allen’s Encyclopedia, vol. 3, p. 214, here designated № 6.
 The provers of the сlinical Society are :
 1. Doctor W. в. Trites, 2d dec. trit.
 2. Mr. J. J. Sturges, 1st dec. trit.
 3. Mr. E. W. Le Roy, 6th dec. trit. (both under supervision of Doctor с. Mohr) ;
 4. Doctor с. в. Knerr, 30th cent. ; and.
 5. Mr. Walter K. Furness (under supervision of Doctor Knerr) 2d dec. trit.

Nosology

 - Intermittent hemicrania, Altschul, Rück. Kl. Erf., vol. 5, p. 82 ; Headache, D. F. and J. с. Moore, N. E. Medorrhinum Gaz., 1869, vol. 4, p. 446 ; Occipito-cervico intercostal neuralgia, Payr, Hom. Klinik, 1869, p. 19 ; Rheumatic headache, H. G. вojanus, Raue’s Rec., 1874, p. 257 ; Scrofulous ophthalmia and keratitis superficialis, Wm. H. вigler (unpublished) ; Malignant angina in scarlatina, Kafka’s Therapie, vol. 1, p. 433 ; Diphtheritis, numerous cases, Findeisen, A. H. Z., vol. 87, p. 113 and 196 ; Diphtheria, A. Neuschafer, A. H. Z., vol. 78, 1869 ; Intermitting diarrhoea, Kafka, Rück. Kl. Erf., vol. 5, p. 410 ; Suffocative attacks in tuberculosis, Kafka, Rück. Kl. Erf., vol. 5, p. 797 ; Epileptiform spasms, Payr, Hom. Klinik, 1869, p. 2 ; Intermittent fever, S. R. Geiser, сin. Medorrhinum Adv., vol. 4, p. 79.

Mental

 Depressed in spirit, with dulness of mind (№ 3).
 Listless after previous fever ; no desire to do anything (№ 2).
 Desire to sit or lie in one place and not be disturbed (№ 2).
 Mental dulness, with inclination to vomit (№ 3).
 Anxiety and nightly delirium. θ Diphtheria.
 The chilly waves are brought on by thinking of them (№ 2).
 Anxiety, with dyspnoea. θ Tuberculosis.
 Greatest anxiety, with unquenchable thirst ; must sit up bent forward, if possible at open window. θ Tuberculosis.
 Child sits up in bed lamenting. θ Keratitis.
 He believes he cannot long endure such utter prostration. θ Epilepsy.
 Irritable mood precedes headache, which is worse by mental and bodily exercise. θ Hemicrania.
 In consequence of fright, left sided hemicrania.
 Confused feeling in head. θ Diphtheria.

Head, face, and ears

 Severe, darting, tortuous pains running up into head and preventing sleep.
 Without previous aura he feels it rushing like lightning through brain and down right side of neck into arm, which is distorted and wrenched so as to crack audibly ; the facial muscles are convulsively drawn, sight and speech cease, consciousness leaves, and he falls to the ground ; the attack is followed by cold sweat, loud eructations and a feeling of utter prostration. θ Epileptiform spasms.
 Confused headache (№ 1).
 Frontal and occipital headache (№ 1).
 Headache affecting occipital protuberance (№ 1).
 Dull headache in frontal region, not relieved by eating (№ 3).
 Neuralgic pain in right temple and above eye, lasting several days, with inclination to move skin over aching place with his hand (№ 5).
 Tearing, boring pain in left side of head, affecting eye, with flickering, pain and lachrymation ; ringing in ears, nausea and vomiting during attack, which regularly appears at midnight ; is subject to furuncles and abscesses which relieve head.
 Burning pain in left occipital protuberance, extending down nape of neck, along shoulder blade and over left half of thorax, producing orthopnea ; attack commences with stretching and yawning and a shaking chill, generally in morning, and lasts until after midnight.
 Bruised feeling all over head after fever and sleep (№ 2).
 Neuralgic pain about head, particularly in temples ; worse in l. side ; better by rubbing aching spots (№ 4).
 Slight painful pressure in forehead and temples (№ 6).
 Slight sudden throbbing of temporal arteries after 1 P. M.
 Intense photophobia and spasms of orbicularis muscles, gushing hot tears, large ulcers attacking each eye, aggravation from midnight until 3 A. M., during which time the child sat up in bed lamenting. θ Keratitis.
 Scrofulous ophthalmia ; worse after 1 A. M.
 Flickering before left eye, with pain and lachrymation. θ Hemicrania.
 Ringing in ears. θ Hemicrania.
 Watery discharge from nose (№ 2).
 Constant running of profuse limpid and watery discharge (№ 2).
 Yellow discharge from nose (№ 2).
 Left nostril fills up when lying on that side (№ 2).
 Nostrils stop up, particularly left, on lying down, preventing breathing through nose (№ 2).
 Nose clearer when prover is in an erect posture and out of doors (№ 2).
 Sneezing, worse sore throat (№ 2).
 Profuse discharge from both nostrils (№ 2).
 Nose stopped up with purulent and bloody substance. θ Diphtheria.
 Corners of nose excoriated. θ Diphtheria.
 Face pale, sallow and bloated. θ Intermittent fever.
 Swelling of submaxillary and parotid glands. θ Diphtheria.
 Blueness of lips. θ Tuberculosis.

Mouth and throat

 Sweetish taste after clearing throat and coughing (№ 2).
 Yellow slimy coating on tongue, with bitter taste (№ 3).
 Soreness and redness of tip of tongue (№ 4).
 Metallic bitter taste in mouth (№ 6).
 Tongue coated thick and brown. θ Diphtheria.
 Burning canker spot inside of left upper lip (№ 4).
 Fetor oris. θ Diphtheritis. θ Scarlatina.
 Post-nasal catarrh ; worse on left side (№ 2).
 Diphtheria, diffused blackish exudation, hoarseness, great prostration, confusion in head, nightly delirium, difficult swallowing, fetid stench from mouth, dry tongue, dry skin, pulse 130, fever assuming a putrid type (№ 3).
 Constant hacking and clearing of throat (№ 2).
 Throat feels sore and inflamed, with a good deal of cough (№ 2).
 Throat feels raw and sore ; worse by coughing and sneezing (№ 2).
 Malignant angina during scarlatina, with paleness of skin, quick exhaustion and rapid destruction of mucous membrane of fauces.
 Diphtheria : fetor oris, swelling of submaxillary glands, frequently also of parotids, violent fever and great prostration.
 Diphtheria : strong fetor oris ; submaxillary glands swollen and painful ; breathing through mouth because nose is stopped up with purulent and bloody substance ; corners of nose excoriated ; tongue coated thick and brown, both tonsils covered with a grey exudation, on right tonsil a bloody ulcer with uneven edges which corresponded to size of a membrane just retched out ; lower half of uvula gangrenous, upper half covered with exudation ; posterior wall of fauces completely covered with exudation ; swallowing of liquids very difficult ; great weakness ; sleeplessness ; pulse small, very frequent.
 Eructations. θ Epilepsy.
 Nausea and vomiting, followed by sleep. θ Hemicrania.
 Hoarseness. θ Diphtheria.
 Aching in bronchial region ; worse left side (№ 4).
 Seemed to prevent diphtheritic membrane from spreading to larynx. θ Malignant scarlatina.

Appetite and food preferences

 No appetite for breakfast after fever in the night (№ 2).
 No thirst with the fever (№ 2).
 Thirst which cannot be appeared ; during attacks of suffocation. θ Tuberculosis.
 Eggs and fish cause painless diarrhoea at once. θ Rheumatic headache.
 She does not like cold water. θ Rheumatic headache.
 Water tastes bitter, or has a disagreeable flavor like the water found in cars (№ 2).

Gastrointestinal tract

 Inclination to vomit, with mental dulness (№ 3).
 Sudden inclination to vomit at 2 P. M., lasting only a few minutes (№ 3).
 Regurgitation of food (№ 4).
 Sensation from stomach through entire intestinal canal as if diarrhoea would set in (№ 4).
 Burning, sore feeling in stomach ; worse on motion, particularly going up-stairs (№ 4).
 Uncomfortable feeling in stomach is better by expanding chest (№ 4).
 Burning in stomach (№ 4).
 Left hypochondriac region enlarged. θ Intermittent fever.
 Abdomen bloated. θ Intermittent fever.
 Sore pain in a small spot, which could be covered with tip of a finger below and to right of umbilicus, coming and going, but continuing all day (№ 1).
 Very severe colic (№ 6).
 Pressure in solar plexus, as if he had eaten tough meat or hard nuts, extending towards back where it changes to a pinching sensation, spine painfully sensitive to touch at this point (№ 6).
 Diarrhoea from malarious poisoning ; stools thin, watery, undigested, offensive, dark or light brown, sometimes with a meal-like sediment.
 From ten to fifteen painless, watery, very offensive stools from 6 to 10 A. M., with burning in anus after each passage ; slightly emaciated, pale and weak.
 Fetid diarrhoea with pains in bowels. θ Intermittent fever.

Urogenital system

 Spasmodic retention of urine ; better by application of hot cloths to chest, which, however, is followed by syncope. θ Occipito-intercostal neuralgia.

Chest organs

 Respiration very free as if thorax was hollow (№ 6).
 Blueness of lips, hands and nails, with attacks of suffocation, which begin in morning and last until noon. θ Tuberculosis.
 Must sit bent forward and if possible at an open window during attack of suffocation ; worse by any other position.
 Dyspnoea with anxiety. θ Tuberculosis.
 Every forenoon at 9 o’clock attacks of suffocating spells.
 Coughing worse sore throat (№ 2).
 Cough with but little expectoration (№ 2).
 Slight cough at long intervals, seems to come from full feeling in chest (№ 2).
 Senile subacute catarrh with periodical fever, generally worse at night.
 Peculiar colicky pain in lower part of left lung felt like a pain from flatulence, comes and quickly passes away, often repeated (№ 1).
 Sharp stitch in lower part of right chest in front ; worse when inspiring, causing him to cry out (№ 1).
 Desire to inflate lungs to their fullest extent to relieve uncomfortable feeling in stomach while riding in open air on a raw, cold day (№ 4).
 The chest feels hollow and respiration freer (№ 4).
 Limbs icy cold ; cold clammy sweat all over ; greatest anxiety and unquenchable thirst ; must sit up, bent forward if possible, at open window. θ Tuberculosis.
 Paralysis of respiratory muscles on left side. θ Intercostal neuralgia.
 Violent neuralgic pain in left mammary region, as though that part was torn with red hot tongs. θ Intercostal neuralgia.
 Aching in intercostal muscles, right side, in locality of sixth and seventh ribs on making inspiration (№ 4).
 Sneezing : worse sore throat ; and coughing worse rawness in throat.

Cardiovascular system

 Angina pectoris, with dropsical symptoms, venous hyperemia and cyanosis.
 Trembling of heart, with rumbling noise, unable to distinguish pulsations, lasting one hour (№ 6).
 Palpitation ; noticed on leaning against back (№ 6).
 Sensation as if heart had stopped (№ 6).
 No perception of beating of heart (№ 6).
 Beat of heart and pulse irregular, numbering 200 per minute (№ 6).
 Pulse cannot be felt on left side (№ 6).
 Beat of heart becomes regular towards noon (№ 6).
 Pulse in radial and temporal arteries 200 (№ 6).
 Pulse small, very frequent. θ Diphtheria.
 Pulse 130. θ Diphtheria.
 Pulse 98, full and strong during fever (№ 2).

Limbs and spine

 Back feels weak as after taking a long journey (№ 2).
 Pain in muscles between left shoulder and neck, as if sprained, on rising from sleep at 4 P. M. 4).
 Painful weariness in shoulder and elbow joints (№ 6).
 Aching in biceps of left arm (№ 1).
 Acute fugitive pain in left olecranon process (№ 1).
 Pain in flexors of left forearm on radial side near elbow (№ 1).
 Palms of hands hot and dry (№ 1).
 Sore, aching fugitive pains in first phalanx of left thumb, the same, but in a less degree, in right (№ 1).
 Blueness of hands and nails. θ Tuberculosis.
 Weariness of lower extremities.
 Gooseflesh on lower extremities, with chilly feeling (№ 2).
 Sore, aching fugitive pain in left leg near knee (№ 1).
 Aching, sore pain in anterior lower two-thirds of left tibia (№ 1).
 Itching on internal malleolus of right foot at 2 A. M. ; on investigation discovered eruption of bright red pimples (№ 4).
 Increased tenderness of corn on left little toe ; had to remove shoe to ease pain (№ 4).
 Limbs icy cold. θ Tuberculosis.
 Desire to sit or lie in one place.
 Desire to move skin over aching place in temple with his hand.
 Lying : on left side, nostril fills up.
 Sitting : bent forward better anxiety and suffocation.
 Leaning against back : palpitation noticeable.
 Erect posture : nose clearer.
 Expanding chest : better uncomfortable feeling in stomach.
 Motion : and going up-stairs worse burning soreness in stomach ; worse intercostal neuralgia.
 Bodily exercise : headache.
 Riding in open air : desire to expand lungs to relieve uncomfortable feeling in stomach.
 Touch : spine sensitive to.
 Rubbing : better aching spots in head.
 Pressure of shoe : worse aching of corn.

Nervous system

 Great prostration. θ Diphtheria.
 Lassitude and fatigue (№ 4).
 Feels as when suffering from partially developed malaria (№ 1).
 Felt sore and ached all over (№ 1).
 Felt like one having taken a long journey (№ 2).
 Great prostration, followed by a deep sleep after an attack of dyspnoea. θ Tuberculosis.
 Epilepsy ; after attack cold perspiration, eructations, and a feeling of such utter prostration that patient believes he cannot endure it long.

Sleep

 Goes to sleep after tea and sleeps heavily all night (№ 4).
 Deep sleep after suffocative attacks. θ Tuberculosis.
 Awakes from sleep exhausted and bathed in sweat after an attack of dyspnoea. θ Tuberculosis.
 Restless until 3 A. M., constantly changing position, particularly as soon as pillow becomes warm (№ 6).
 Sleep frequently interrupted (№ 6).
 Sleeplessness. θ Diphtheria.
 Nightly : delirium in diphtheria.
 At night : senile subacute catarrh.
 From midnight until 3 A. M. : ophthalmia.
 From morning until after midnight : burning pain in head with chills.
 At 2 A. M. : itching eruption on internal malleolus of right foot.
 Until 3 A. M. : restless.
 At 4 A. M. : sprained feeling in muscles of back.
 From morning to noon : suffocation, with blueness of lips, hands and nails.
 In morning : broken-up feeling after fever, no appetite for breakfast.
 From 6 to 10 A. M. : diarrhoea.
 At 9 A. M. : suffocating spells.
 Towards noon : beat of heart becomes regular.
 Forenoon : chill at irregular hours.
 Towards midnight : fever following chilliness, pulse 90.
 After 1 P. M. : throbbing of temporal arteries.
 At 2 P. M. : sudden inclination to vomit.
 After 8.30 P. M. : chilliness with goose-flesh.

Common symptoms

 Hot cloths to chest : better retention of urine but cause syncope.
 Warmth of pillow : worse restlessness.
 Open window : sits there to better anxiety and suffocation.
 On a raw, cold day, while riding, desire to expand lungs to relieve uncomfortable feeling in stomach.
 Damp weather : is sensitive to it, and feels chilly. θ Rheumatic headache.
 Cool part of bed : worse chilliness.
 Inclination to throw off covers and open windows : with fever towards midnight.
 As if diarrhoea would set in ; as if heart had stopped ; as if torn with red hot tongs in left mammary region ; as after a long journey, weakness in back ; as if he had eaten tough meat or hard nuts, in solar plexus ; as when suffering from partially developed malaria ; as if thorax was hollow.
 Pains : in flexors of left forearm.
 Acute pain : in left olecranon process.
 Neuralgic pain : in right temple and above eyes ; about head, particularly in temples ; in left mammary region.
 Stitch : in lower right chest.
 Darting : running up into head.
 Tearing : in left side of head and eye.
 Boring : in left side of head and eye.
 Burning : in left occipital protuberance to nape of neck, along shoulder blade and over left half of thorax ; canker spot in upper lip ; in stomach ; in anus.
 Colicky pain : in abdomen ; in lower part of left lung.
 Raw feeling : in throat.
 Sore pain : in a small spot below and to right of umbilicus.
 Sprained pain : in muscles of back between shoulder and neck.
 Pinching : back, in region of solar plexus.
 Pressure : in forehead and temples ; in solar plexus.
 Tenderness : of corn on left little toe.
 Aching : in bronchial region ; in intercostal muscles right side ; in biceps ; in phalanges of thumbs ; in left leg near knee ; in anterior lower left tibia ; all over.
 Dull pain : in frontal region.
 Bruised feeling : all over head.
 Sore feeling : in throat ; in stomach ; all over ; tip of tongue.
 Broken-up feeling : in morning after fever.
 Lightning-like sensation runs through brain and down r. side of neck into arm.
 Tortuous pains : run up into head.
 Hollow feeling : in chest.
 Uncomfortable feeling : in stomach.
 Weariness, painful : in shoulder and elbow joints ; in lower extremities.
 Throbbing : of temporal arteries.
 Chilly feeling : with goose-flesh all over body.
 Itching : on internal right malleolus.
 Dropsical symptoms, venous hyperemia and cyanosis.

Fever

 Chilly feeling like cold waves after 8 1/2 P. M. in bed, with gooseflesh all over body, but particularly on legs (№ 2).
 Chilliness coming in waves, with restlessness ; worse by moving hands and feet to a cool part of bed, also by thinking of it (№ 2).
 Chill always in forenoon, not at a regular hour, however ; sometimes once every day, again every other day ; sometimes paroxysms would close with perspiration, sometimes without ; before the attack headache, yawning and stretching. θ Intermittent fever.
 After chilliness, feverish towards midnight, pulse 98, full and strong, with inclination to throw off covers and open windows, no sweat (№ 2).
 Feverish all the time, but more so at night (№ 2).
 No sweat after fever, but weak, broken-up feeling in morning and no appetite for breakfast (№ 2).
 Violent fever with great prostration. θ Diphtheria. θ Malignant scarlatina.
 Periodically : furuncles and abscesses. θ Hemicrania.
 Like cold waves : chilliness in evening.
 At long intervals : slight cough from full feeling in chest.
 Coming and going quickly : peculiar colicky pain in lower part of left lung, often repeated.
 Coming and going, all day : sore pain in spot below and to right of umbilicus.
 Lasting a few minutes : inclination to vomit.
 Lasting one hour : tremor of heart.
 Every day or every other day : chill ; attacks of suffocation.
 Lasting several days : neuralgia in head.
 Left : hemicrania ; boring in side of head, affecting eye ; burning in occipital protuberance, down nape of neck, along shoulder blade and over half of thorax ; neuralgia about head ; flickering before eye ; nostril fills up when lying on side ; canker spot inside upper lip ; post-nasal catarrh.
 Right : rushing like lightning through brain and down side of neck into arm ; neuralgia in temple and above eye ; diphtheritic ulcer on tonsil ; sore pain in small spot to right of umbilicus ; sharp stitch in lower part of chest, in front ; aching in intercostal muscles, locality of sixth and seventh ribs ; pains in thumb ; itching eruption on internal malleolus of foot.

Skin

 Recommended in plague by Lorbacher.
 Dry skin. θ Diphtheria.
 Gooseflesh over whole body, particularly lower extremities (№ 2).
 Pallor of skin, with rapid exhaustion. θ Scarlatina.
 Cold, clammy sweat all over. θ Tuberculosis.
 Cold perspiration after attacks. θ Epilepsy.
 Periodical furuncles and abscesses, which relieve the head. θ Hemicrania.

Patient type and constitution

 Albert S., at. 4 ; had chills for two weeks ; intermittent fever.
 A stout girl, at. 10 ; diphtheria.
 A young lady of slender build, at. 20 ; diphtheria.
 A tuberculous woman, at. 30 ; suffocative attacks.
 Strong man of sanguine temperament ; intermittent hemicrania of three years’ standing.
 A man ; epileptiform spasms of nine years’ standing, caused by masturbation and use of spirituous drinks.
 Woman, at. 50 ; diarrhoea.
 Lady, at. 58 ; hydrogenoid constitution ; rheumatic headache.

Dif. diagnostics

 Compare : Apis (diphtheria), Arsen. (neuralgias, diarrhoea, tuberculosis), сinchon. (diarrhoea, suffocative attacks in tuberculosis).
  .

Analogs by action

Included in the composition

Manufacturers (or distributors) of the drug

Доктор Н
Фитасинтекс
ПиК-Крым
Вербена
ОЛЛО
Natura Pharma
ФармаРус
42a96bb5c8a2acfb07fc866444b97bf1
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