Compatibility «Acetylsalicylic acid+Caffeine+Paracetamol» and «Furosemide»

• Interactions Acetylsalicylic acid+Caffeine+Paracetamol with Furosemide

  • Dangerous interactions
    • ⓘ When high doses of salicylates are prescribed, the risk of salicylism (competitive renal excretion) increases, cardiac glycosides - hypokalemia and associated arrhythmia, corticosteroids - electrolyte imbalance.
    • ⓘ In patients with hypovolemia and dehydration (including while taking furosemide), NSAIDs can cause the development of acute renal failure.
  • Negative interactions
    • ⓘ Increases the toxicity of methotrexate, reducing its renal clearance, the effects of narcotic analgesics (codeine), oral antidiabetic drugs, heparin, indirect anticoagulants, thrombolytics and inhibitors of platelet aggregation, reduces the effect of uricosuric drugs (benzbromarone, sulfinpyrazone), hypotensive agents, diuretics (spironolactone, furosemide).
    • ⓘ Nonsteroidal anti-inflammatory drugs (NSAIDs) - NSAIDs, including acetylsalicylic acid, can reduce the diuretic effect of furosemide.
    • ⓘ Furosemide may increase the toxicity of salicylates.
    • ⓘ Furosemide (C03CA01) + Butadione, salicylates and other non-narcotic analgesics => Attenuation of the diuretic and hypotensive effects of furosemide.
  • Positive interactions
    • ⓘ Diuretics in combination with acetylsalicylic acid in higher doses.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 169,994,378 possible combinations of drugs and their components were found 412,530 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2024-12-19

Category - medicine