Compatibility «Aliskiren» and «Metformin»
Between «Aliskiren» and «Metformin» found 1 dangerous and 2 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Metformin |
| ✘Aliskiren Analogs | |
| ✘Metformin [Metformin and more 1Metformin hydrochloride] Analogs |
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Interactions Aliskiren with Metformin
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Dangerous interactions
- Since, when used together, aliskiren does not have a significant effect on the pharmacokinetics of atorvastatin, valsartan, metformin, amlodipine, it is not necessary to change the doses of Rasilez or the above drugs at the same time.
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Negative interactions
- Valsartan and metformin reduce the Cmax and AUC of aliskiren by 28%; amlodipine, cimetidine increase the Cmax and AUC of aliskiren by 29% and 19%, respectively.
- When using aliskiren with one of the following drugs, it is possible to change the max'>Cmax or AUC: valsartan (decrease by 28%), metformin (decrease by 28%), amlodipine (increase by 29%), cimetidine (increase by 19%).
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Dangerous interactions
Decoding the colors of interactions and contraindications
| Dangerous | — | a pronounced negative interaction or contraindication. |
| Negative | — | negative interaction or side effect that may reduce effectiveness. |
| Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication. |
| No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
| Unclear | — | the system failed to pre-assess the danger. |
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Additional information
- Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
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- See the compatibility of drugs with alcohol (enter it as a drug).
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- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 170,027,037 possible combinations of drugs and their components were found 412,563 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2026-01-01
Category - medicine