Compatibility «Sorbifer Durules» and «Tot’hema»

• Interactions Sorbifer Durules with Tot’hema

  • Dangerous interactions
    • ⓘ It cannot be combined with taking other iron preparations, in pm for parenteral administration.
  • Negative interactions
    • ⓘ - cimetidine (when combined with the drug Sorbifer Durules with cimetidine, a decrease in gastric acidity caused by cimetidine reduces iron absorption).
    • ⓘ When using Sorbifer Durules with tea, coffee, eggs, dairy products, bread made from coarse flour, cereal grains or fiber-rich foods, iron absorption may decrease.
    • ⓘ - iron preparations and other drugs containing iron, - accumulation of iron in the liver is possible, the probability of iron overdose increases;.
    • ⓘ - chloramphenicol - the effectiveness of iron preparations decreases.
    • ⓘ Ferrous sulfate and Ferrous gluconate belong to the same pharmaceutical group: Iron preparations.
    • ⓘ Ferrous sulfate and Ferrous gluconate belong to the same pharmaceutical group: Oral preparations of divalent iron.
    • ⓘ Improves intestinal absorption of iron preparations (converts trivalent iron into divalent iron); may increase iron excretion when used concomitantly with deferoxamine.
  • Positive interactions
    • ⓘ - dietary supplements containing calcium or magnesium, as well as antacids containing aluminum, calcium or magnesium (they form complexes with iron salts, worsening the.
    • ⓘ - methyldopa (levorotatory) (with the combined use of iron salts (sulfate and iron gluconate) with methyldopa, probably due to the formation of chelate complexes, the bioavailability of methyldopa decreases, which may worsen its antihypertensive effect);.
    • ⓘ Improves intestinal absorption of iron preparations, as well as iron from food (by converting Fe (III) to Fe (II).
    • ⓘ Improves intestinal absorption of iron preparations (due to the conversion of trivalent iron into divalent iron).
  • Unclear interactions
    • ⓘ Ferrous sulfate + Ferrous gluconate analgin and citramon are used together in LifePak, Floradix Liquid Iron Formula.
    • ⓘ Ferrous gluconate + Ascorbic acid analgin and citramon are used together in 5 preparations.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,027,037 possible combinations of drugs and their components were found 412,563 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-01-01

Category - medicine