Compatibility «Ordiss N» and «Моноинсулин ЧР»

• Interactions Ordiss N with Моноинсулин ЧР

  • Negative interactions
    • ⓘ When treated with thiazide diuretics, glucose tolerance may decrease, and therefore it may be necessary to select the dose of hypoglycemic drugs (in pm insulin).
    • ⓘ The hypoglycemic effect of insulin is weakened by glucagon, somatropin, estrogens, oral contraceptives, glucocorticosteroids, iodine‑containing thyroid hormones, thiazide diuretics, loop diuretics, heparin, tricyclic antidepressants, sympathomimetics, danazol, clonidine, epinephrine, H₁-histamine receptor blockers, blockers of 'slow' calcium channels, diazoxide, morphine, phenytoin, nicotine.
    • ⓘ Hypoglycemic agents for oral administration and insulin.
    • ⓘ Thiazide diuretics affect glucose tolerance (hyperglycemia may develop) and reduce the effectiveness of hypoglycemic agents (dose adjustment of hypoglycemic agents may be required).
    • ⓘ The need for insulin may increase due to medications with hyperglycemic effects, such as glucocorticosteroids, thyroid hormone replacement therapy, growth hormone, danazol, beta₂‑adrenomimetics (for example, ritodrine, salbutamol, terbutaline), thiazide diuretics.
    • ⓘ Antidiabetic drugs (Insulin preparations, sulfonylurea derivatives (bucarban, butamide, etc.), biguanides (glybutide, etc.)) + Glucocorticoids, deoxycorticosterone, diuretics that remove potassium (dichlothiazide, etc.), corticotropin, cardiac glycosides => Weakening of the effect of antidiabetic drugs.
    • ⓘ The need for insulin may decrease when taking medications with hypoglycemic effects, such as oral hypoglycemic drugs, salicylates (for example, acetylsalicylic acid), some antidepressants (monoamine oxidase inhibitors), some angiotensin converting enzyme inhibitors (captopril, enalapril), angiotensin II receptor blockers, non‑selective beta blockers and alcohol.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
• Why do I need to
  • Avoid dangerous prescriptions for your patients.
  • Check the contraindications.
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  • See the compatibility of drugs with alcohol (enter it as a drug).
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,028,852 possible combinations of drugs and their components were found 412,565 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-01-22

Category - medicine