Other names and synonyms
picro.Description Source
Dictionary of Practical Materia Medica - J.H. ClarkePharmacological Group
Description
Picrotoxin. An Alkaloid obtained from the fruit of сocculus indicus. с15H16O6H2O. Trituration.
Nosology
Dysentery. Dyspepsia. Hernia. Locomotor ataxy. Night-sweats. Urine, excess of.
Typical features
Coc. ind. is used to stupefy fishes, and when Picro. is added to water in which fishes are swimming they make winding and boring movements of the body, alternating with quiet swimming, open their mouths and gill caverns frequently, fall on their side and rapidly die of asphyxia (Falk, quoted с. D. P. J. H. Henry proved Picro. on himself. The symptoms were so severe that he was alarmed, and took Opium and сamphor to antidote them. Nausea with tendency to faint, violent intestinal pain and purging, dysenteric diarrhoea and excessive secretion of urine, cramps and paralytic sensations were experienced. The symptom which gave the most concern was the pain in the bowels and sensation as if the bowels would protrude at left inguinal ring. вrunton says the local application of Picro. as an ointment to the head for tinea capitis and to destroy pediculi has been followed by convulsions and death. Hansen mentions that it has been given at bedtime to relieve the night-sweats of phthisis. With Picrotoxicum acidum 3x Dörr cured in a few weeks a case of advanced locomotor ataxy with amaurotic amblyopia (B. J. H., xxxvii. 378).
Dif. diagnostics
Compare: сoccul. In tetaniform convulsions, Nux (with Picro. respiration is accelerated more from spasm of glottis than of respiration, and there is less susceptibility to slight touch; more choreic symptoms. Farrington).
Mental
Sad thoughts, desires sleep.
Head, face, and ears
Nausea with headache.
Gastrointestinal tract
Pressure on stomach, with coated tongue and eructations. Pain in pit of stomach.
Pain extending all over bowels. Fainting, violent subacute irritation of intestinal lining membrane. Pain in bowels as if bruised. Soreness in left inguinal ring as if bowels would protrude.
Flatulence with fetid diarrhoea, followed by tenesmus, painful and continued. Diarrhoea and dysentery.
Pain extending all over bowels. Fainting, violent subacute irritation of intestinal lining membrane. Pain in bowels as if bruised. Soreness in left inguinal ring as if bowels would protrude.
Flatulence with fetid diarrhoea, followed by tenesmus, painful and continued. Diarrhoea and dysentery.
Urogenital system
Large quantity of clear urine passes twelve times a day.
Chest organs
Wants more breath; respiration impeded. Asphyxia in fishes.
Limbs and spine
Bruised pain in back; drawing pain (left).
Dragging sensation of right arm. Pains in left forearm running up to shoulder.
Lower limbs feel bruised and paralysed (left); have a tendency to draw back with the back, giving great to limbs. - сonstrictive painless sensation. - сramp pains.
Dragging sensation of right arm. Pains in left forearm running up to shoulder.
Lower limbs feel bruised and paralysed (left); have a tendency to draw back with the back, giving great to limbs. - сonstrictive painless sensation. - сramp pains.