Compatibility «Mycophenolate mofetil» and «Amoxicillin+Clavulanic acid»
Between «Mycophenolate mofetil» and «Amoxicillin+Clavulanic acid» found 2 dangerous and 3 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Amoxicillin+Clavulanic acid |
✘Mycophenolate mofetil Analogs | |
✘Amoxicillin+Clavulanic acid [Amoxicillin and more 1Clavulanic acid] Analogs |
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Interactions Mycophenolate mofetil with Amoxicillin+Clavulanic acid
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Dangerous interactions
However, alcohol consumption during treatment with beta-lactam antibiotics causes a disulfiram-like reaction in some patients. Therefore, alcohol consumption should be avoided during and for several days after treatment with a combination of amoxicillin + clavulanic acid for injection. -
Negative interactions
In patients after kidney transplantation, in the days immediately after oral administration of ciprofloxacin or amoxicillin in combination with clavulanic acid, a decrease in the minimum concentration of IFC by 54% is observed. It has been reported that the concentration of the active metabolite, mycophenolic acid, decreased by about 50% after the start of oral administration of the combination of amoxicillin + clavulanic acid in patients receiving mycophenolate mofetil. Antibiotics that lead to the death of bacteria producing β-glucuronidase in the intestine (for example, antibiotics from the group of aminoglycosides, cephalosporins, fluoroquinolones and penicillins) can disrupt the hepatic-intestinal recirculation of IFC/IFC, which, in turn, can lead to a decrease in systemic exposure to IFC. -
No interactions
Thus, a dose change of mycophenolate mofetil is usually not required in the absence of clinical data on graft dysfunction. There is no information about the simultaneous intravenous use of a combination of amoxicillin + clavulanic acid and alcohol. -
Unclear interactions
Ciprofloxacin or amoxicillin in combination with clavulanic acid. Mycophenolate mofetil. Alcohol.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,974,420 possible combinations of drugs and their components were found 412,510 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-05-02
Category - medicine