Compatibility «Erythromycin» and «Aminophylline-Eskom»
Between «Erythromycin» and «Aminophylline-Eskom» found 4 dangerous and 6 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Aminophylline-Eskom |
✘Erythromycin Analogs | |
✘Aminophylline-Eskom [Aminophylline and more 2Theophylline, Ethylenediamine] Analogs |
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Interactions Erythromycin with Aminophylline-Eskom
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Dangerous interactions
Macrolides (J01FA) + carbamazepine, phenytoin, valproic acid, aminophylline, caffeine, theophylline => Increased concentration of these drugs in blood serum and increased risk of their toxicity. Erythromycin (J01FA01) + Theophylline, euphyllin => Increased likelihood of theophylline's toxic effects (nausea, vomiting, diarrhea, headache, dizziness. In severe cases of arrhythmias and seizures). Aminophylline (R03DA05) + Erythromycin => In children, there is a risk of severe convulsive reactions due to slowing down the biotransformation of aminophylline. It potentiates the effects and toxicity of antihistamines, ergot alkaloids, theophylline and benzodiazepines, digoxin, anticoagulants of an indirect type of action, carbamazepine, cyclosporine, hexobarbital, phenytoin, disopyramide, lovastatin and bromocriptine. -
Negative interactions
When used concomitantly with macrolide antibiotics, lincomycin, allopurinol, cimetidine, isoprenaline, enoxacin, small doses of ethanol, disulfiram, fluoroquinolones, recombinant interferon alpha, methotrexate, mexiletine, propafenone, thiabendazole, ticlopidine, verapamil and during influenza vaccination, the intensity of action of aminophylline may increase, which may require a decrease in its doses. Oral contraceptives (estrogen-containing), antidiarrheal drugs, intestinal sorbents weaken, and H2-histamine blockers, fluoroquinolones, BCC, beta-blockers, mexiletine, erythromycin enhance the effect (bind to the cytochrome P450 enzymatic system and slow down the biotransformation of aminophylline). When used concomitantly with macrolide antibiotics, lincomycin, allopurinol, cimetidine, isoprenaline, enoxacin, small doses of ethanol, disulfiram, fluoroquinolones, recombinant interferon-alpha, methotrexate, mexiletine, propafenone, thiabendazole, ticlopidine, verapamil and during influenza vaccination, the intensity of action of aminophylline may increase, which may require a decrease his doses. Increases the concentration of theophylline in the blood: it may be necessary to reduce the dose of theophylline. Cimetidine, allopurinol, cyclosporine A, macrolide antibiotics, oral contraceptives, anti-influenza serum, a diet low in protein and high in carbohydrates - reduce clearance and increase the risk of side effects. When used concomitantly with macrolide antibiotics, allopurinol, cimetidine, oral contraceptives, isoprenaline, lincomycin, theophylline clearance decreases.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
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Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,974,420 possible combinations of drugs and their components were found 412,510 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-05-02
Category - medicine