Compatibility «Fentanyl» and «Selegiline»
Between «Fentanyl» and «Selegiline» found 8 dangerous and 1 negative interaction, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Selegiline |
✘Fentanyl Analogs | |
✘Selegiline Analogs |
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Interactions Fentanyl with Selegiline
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Dangerous interactions
Opiates, sedatives, hypnotics, phenothiazines, tranquilizers, anesthetics, muscle relaxants, antihistamines that cause sedation, alcohol and other depressants increase the likelihood of side effects (central nervous system depression, hypoventilation, hypotension, etc.;). Dinitrogen oxide increases muscle rigidity, antihypertensive agents increase hypotension, and MAO inhibitors increase the risk of severe complications. It is not recommended to use a transdermal patch with fentanyl in patients who require simultaneous administration of MAO inhibitors. Simultaneous use of a transdermal patch with SSRIs or SSRIs or MAO inhibitors is not recommended. Opioid narcotic analgesics (N02A) + Selegiline; Moclobemide; Pirlindole (N06AG) => The narcotic effect of opioid analgesics is enhanced. In parallel, undesirable effects such as respiratory depression, sudden fluctuations in blood pressure, hyperthermia, loss of consciousness, convulsions may occur. Opioid narcotic analgesics (N01AH01) + CNS depressants; hypnotics, neuroleptics, benzodiazepine tranquilizers, etc. => Respiratory depression, bradycardia, deep coma, possible death. Selegiline; Moclobemide; Pirlindole (N06AG) + Opioid narcotic analgesics (N02A) => Dangerous rise in blood pressure. The effects of opioid analgesics are increasing — hypotension, respiratory depression. Selegiline (N04BD01) + Opioid narcotic analgesics (N02A) => Severe toxic reaction, seizures, coma and death. -
Negative interactions
Therefore, fentanyl should not be taken during the entire period of use of MAO inhibitors, as well as for 14 days after their withdrawal. -
Unclear interactions
MAO inhibitors.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,972,605 possible combinations of drugs and their components were found 412,508 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-04-11
Category - medicine