Compatibility «Glucovance» and «Acarbose»
Between «Glucovance» and «Acarbose» found 1 dangerous and 12 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Acarbose |
✘Glucovance [Glibenclamide+Metformin and more 2Glibenclamide, Metformin] Analogs | |
✘Acarbose [Acarbose] Analogs |
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Interactions Glucovance with Acarbose
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Dangerous interactions
Antifungal agents of systemic action (azole derivatives), fluoroquinolones, tetracyclines, chloramphenicol (inhibits metabolism), H2-blockers, beta-blockers, ACE inhibitors, NSAIDs, MAO inhibitors, clofibrate, bezafibrate, probenecid, paracetamol, ethionamide, anabolic steroids, pentoxifylline, allopurinol, cyclophosphamide, reserpine, sulfonamides, insulin - potentiate hypoglycemia. -
Negative interactions
Associated with the use of all hypoglycemic agents. Precautions: the patient should be warned about the need for self-monitoring of blood glucose; if necessary, adjust the dose of a hypoglycemic agent during simultaneous use of a neuroleptic and after discontinuation of its use. Precautions: the patient should be warned about the need for self-monitoring of blood glucose; if necessary, the dose of hypoglycemic agent should be adjusted during simultaneous use of GCS and after discontinuation of their use. Beta1-adrenoblockers, clonidine, reserpine, guanethidine and sympatholytics: mask some symptoms of hypoglycemia - palpitations and tachycardia. The patient should be warned about the need for self-monitoring of blood glucose; it may be necessary to adjust the dose of hypoglycemic agents during simultaneous treatment with fluconazole and after discontinuation of its use. Antibacterial drugs from the sulfonamide group, fluoroquinolones, anticoagulants (coumarin derivatives), MAO inhibitors, chloramphenicol, pentoxifylline, lipid-lowering drugs from the fibrate group, disopyramide: the risk of hypoglycemia against the background of glibenclamide use. Barbiturates, phenothiazines, diazoxide, glucocorticoid and thyroid hormones, estrogens, progestogens, glucagon, adrenomimetic drugs, lithium salts, nicotinic acid derivatives and saluretics weaken the hypoglycemic effect. When such drugs are discontinued in patients receiving acarbose in combination with sulfonylurea derivatives or insulin, patients should be carefully monitored for signs of hypoglycemia. The use of acarbose in patients receiving sulfonylurea derivatives or insulin, which can cause hypoglycemia, may lead to a further decrease in blood glucose levels and increase the likelihood of hypoglycemia. If hypoglycemia occurs, appropriate adjustments should be made to the dosage of these drugs. Very rarely, isolated cases of hypoglycemic shock have been reported in patients treated with acarbose in combination with sulfonylurea derivatives and/or insulin. Discontinuation of such drugs in patients receiving metformin requires careful monitoring of their condition due to the possibility of hypoglycemia.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
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Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,974,420 possible combinations of drugs and their components were found 412,510 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-05-02
Category - medicine