Cundurango

 Gonolobus condurango, Trinana (Journ. de Pharm. et de сhem., 4 ser., v. 345).
 Natural order: Asclepiadaceae.
 Native name: (Spanish), Mata-perro.
 Preparation: Tincture and triturations of the bark of the stem (vine).

 I feel miserable (eighth day).

 Vertigo. Very slight vertigo, with a faint perception of headache across the top of forehead (ninth and tenth days).
 Very great dizziness on stooping, or turning the head (fifth day). General Head. Slight headache (thirty-second day). In the morning I have a bad headache, principally in the upper part of the left half of my forehead; it is just dull, and as it were bigger (twenty-second day). Forehead. Dull feeling in the forehead (eleventh and twelfth days). Almost constant dull sensation across the forehead (thirteenth day). A long-lasting impression, as if my forehead were very broad and high (twelfth day). A feeling as if the left half of my forehead were higher than the right half, i. e., in the left half there is a little heaviness, while the right is clear, and hence they feel different (fifteenth day). slight frontal headache (forty- seventh day). Rather bad frontal headache all day (thirty-first day). Slight headache at the top of my forehead, lasting eighteen hours (sixth and seventh days). Have had a very bad dull headache all day along the top part of my brow and hairy scalp, disappearing early in the evening (fifth day). Temple.
 Violent pain in the left temple, which spread over the upper part of the brain to the right side of the head, feeling as if some one was pulling up the upper part of the skull, with one half of the brain, at 10 p.m; pain increased up to 6 o’clock , at which time it abated (fifth day). External Head. A large pimple on the scalp (eleventh day).
 Eye.
 In the evening there were objects before my right eye resembling black serpents, jumping in all directions. On closing the left eye I found that I could not see; it seemed as though I was looking through a dense fog. At 7.45 I had my eye examined by two physicians, who could not discover anything wrong. At this time the appearance before the eye was like two black horns, with large black balls on the upper ends, and a mound of crystals between them, their tops tapering off, and tipped with black (fifth day). When I awoke in the morning the obstruction in front of the eye appeared of the shape of a pear, with the large end up. Looking towards the light it appeared red, and on looking from the light it appeared to be purple (eleventh day).
 Black spot have nearly disappeared; had the appearance of curled hair in front of the right eye, and a blur before the left eye, which caused the letters to run together (twelfth day). I had my eye examined by an oculist, who found the retina very much congested (thirteenth day). The ball before my eye continued to diminish in size from day to day until the ninety-ninth day, so that I could see tolerably clearly, up to which time I was not able to recognize any one in the street with my left eye closed.
 Nose.
 Objective. Discharge of a good deal of glairy mucus from the nostrils, alternating with a feeling of unusual dryness of the Schneiderian membrane (second day). Subjective. The Schneiderian membrane is at times very dry, the nose stuffed up, and then a great discharge of mucus comes on (thirteenth day).
 Within ten minutes after a dose the same old sensation in the nose; I cannot well describe it, but on pronouncing the French nasal sounds on, en, in, oin, I seem to be able to do it with great perfection. It is a sort of nasal feeling; I fancy those with ozaena must feel so (twenty-eighth day); nose slightly uncomfortable (twenty-ninth day. Peculiar stiffness is my nose for many weeks, six or seven weeks. Slight pressive or full feeling in the bridge of the nose (ninth day) Smell. The smell and taste of the drug are getting very disagreeable to me (tenth day).
 Face.
 Those around me tell me I do not look well (tenth day). Lips look unusually red (eleventh and twenty-ninth days); under one unusually red (forty-seventh day). A painful crack in the right corner of the mouth, appeared about the third day; it healed in two or three days.

 Tongue. Tongue unusually clear and red (twenty-ninth day).
 Small, painful pustule on the right side of the tip of the tongue, on the upper surface towards the edge (twelfth day); the next day the right side of the tip of the tongue is slightly painful, but the wee pustule has broken and seemingly discharged.
 Very slight pain in left half of tongue (fifteenth day). Taste.
 Very strong taste of drug in my mouth, making me draw a wry face (after first dose); very nasty taste (After second dose), (fifteenth day).
 Throat.
 Aching in the throat, which extended to the stomach, with great burning in the stomach. For weeks past I have had a sore throat, which gets no worse and no better, and medicine seems to do it no good; the tonsils are slightly enlarged, but otherwise I can see nothing in the throat (seventy-first day). I do not remember having had a sore throat since I was a lad. I have been attending diphtheria.

 Abdomen.
 Hypochondria. Pain in the right hypochondrium (fifteenth day).
 About 12, noon, several times quite severe pain in the right hypochondrium, lasting over several minutes (fifteenth day).
 General Abdomen. Emission of flatus (fifteenth day). Painful foul-smelling flatus, in the afternoon (fourteenth day).

 Appetite. Anorexia (thirteenth day). A little nausea (sixth and eighth days). Slight nausea arising from right hypochondrium (tenth day).

 Urine scanty (fourth, thirteenth, and forty-seventh days).
 Urine high-colored and loaded with phosphates (eighth day).
 Sexual organs.
 Sexual appetite depressed (thirteenth day).

 Snored very badly (seventh night).

 Constrictive pain at the heart (tenth day). On rising in the morning, slight, sharp, distinct pain in the heart, no anxious feeling with it; it lasted only a minute or so, and shortly after there was a passage of flatus (sixth day).

 Back.
 Pain in left scapula (twenty-ninth day). Severe but transient pain in left scapula (fifteenth day). Pain in left shoulder- blade, then a little in the right one, dull and continuous (tenth day). Dull, heavy, continuous pain in the left shoulder-blade (eleventh day). Dull pain across small of back (eighth day).
 Superior Extremities.
 While driving my round this morning I once or twice felt a sharp pain in my left shoulder posteriorly (twenty-ninth day). While writing, a peculiar tingling in the fingers of my left hand, lasting ten minutes (twenty-ninth day).

 Do not feel well (eleventh day), After the dose took a usual walk, during and after which I felt very poorly (forty sixth day),. While writing, a peculiar tingling in the fingers of my left hand, lasting ten minutes (twenty-ninth day),.

 Skin.
 Objective. Some small, congenital, warty excrescences on my body seem unusually large; they look red and fresh (thirty-second day). Eruptions, Dry. A few erythematous blotches in the face (eighth day). A new blotch over clavicle (thirty-second day).
 There are several blotches on the skin of the upper arms, more on the left (seventeenth day); they still persist and are very bright (twenty-second day);still visible (thirty-second day); after growing nearly invisible they again become red, and there are two new blotches on the left arm, one just below the elbow and the other on the wrist (forty-seventh day); gradually getting pale, but are still visible (seventy-first day). Good many pimples on the thighs (thirteenth day). Two big pimples, like incipient boils, on the front surface of my left thigh (fourth night); withering next day. Eruptions, Pustular. On rising in the morning, I notice a very small pustule, size of a pin’s head, between my eyebrows, and also one on the right side of my nose; washing cleared them away, and a minute portion of blood appeared; there was likewise a pimple on the tip of my nose (thirteenth day). On rising, I perceive a minute pustule on the border of the tip of the tongue to the right of the mesial line, also a tiny pustule on the right cheek, and two similar pustules on the skin of the abdomen, just to the right of the median line, and here, still further to the right, a few tiny papules (fifteenth day). The pustules persist, but are fading; one of the pustules near the acromion became as big as a large pea and filled with pus, but is did not ripen or break, notwithstanding rubbing it daily after my bath with a rough towel (twenty-eighth day); still visible (thirty-second day); have had a good many extremely indolent pimples, one or two on my chest, as large as peas; there is one on the left side of my nose which seems likely to remain; it has already been there more than a week; there is a large one on my chest, just on the manubrium sterni, which is nearly a month old, and is exfoliating (seventy-first day).

 Sleep & Dreams.
 Sleepiness. Sound dreamy sleep (twenty-eighth night).
 Sleeplessness. Sleep transient (twenty-ninth day). Have had restless, dreamy sleep (fourth day). Had a poor night (seventh night). Had a bad night, especially towards morning (eleventh night). Had a very bad night; tossed about to and fro all night, and seemed, nevertheless, rested in the morning (tenth, night).
 Uneasy in the night and slept badly (sixth night). Dreams.
 Dreamy night (forth-sixth night). Very dreamy night (thirty- first night).

 A feeling of warmth throughout the body, obviously from the imbibed spirit, (fifteenth day).

 Conditions -Aggravation.
 (Morning), Headache on rising, pain in heart.
 (Forenoon), At 10 o’clock, pain in temple; pain in left shoulder.
 (About noon), Pain in right hypochondrium.
 (Afternoon), Foul-smelling flatus.
 (Stooping), Dizziness.
 (Turning head), Dizziness. While walking), Felt very poorly. While writing), Tingling in fingers.

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