Parthenium hysterophorus

 Parthenium hysterophorus. вitter-broom. Escoba amarga. N. O. сompositae (tribe Heliantheae). Tincture of the dry plant. Trituration or solution of the alkaloid Parthenia.

 Abortion. Amenorrhoea. сheyne-Stokes breathing. Debility. Dyspepsia. Ear, affections of. Fevers. Headache; extending to nose. Liver, pain in. Milk, increased. Neuralgia, periodic. Salivation. Spleen, affections of. Syncope. Toothache. Vision, disordered.

 E. Fornias brought Parthen. to light (H. R., i. 42, 71). It is a сuban remedy of great repute in the treatment of fevers. An alkaloid Parthenia was isolated by с. J. Ulrice, of Havana, and Doctor J. L. Duenas published experiments with this on the human organism and on animals. Doctor в. H. в. Sleight proved increasing doses of the Ø tincture, and later on of 6x, which reproduced most of the symptoms of the first proving. The Schema is made up chiefly of Sleight s symptoms; additions from Duenas being marked (D). Doctor Ramirez Tovar has reported these cures by Parthenia: (1) A lady living in the lower part of the city, where the rain leaves channels of infection, had daily attacks of intermittent, more intense each day. One grain of the alkaloid was divided into six powders, one every hour after the attack. No further attacks. The patient was nursing at the time, and she noticed a marked increase of milk in the breasts. Half a grain divided into five doses completed the cure. (2) A tailor, 30, moved to lower part of the city, and contracted tertian intermittent, the fourth seizure being attended with much pain in left hypochondrium. One grain in five doses cured, though the conditions were unchanged. The removal of this left hypochondriac pain is important in connection with вurnett s experience with Helianthus. (3) Girl, 6, lymphatic, living near the beach of the harbour, ill for seventeen days with malaise, loss of appetite, sleepiness, and fever. Had had Quinine internally and externally and was wasting visibly. The alkaloid, aided by a tonic wine prepared from the extract of the plant, cured. (4) Man, 45, of delicate constitution, poorly nourished, straw-yellow face, yellow sclerotics, enlarged liver and spleen, spleen painful to pressure. Had had fever in Panama, had taken Quinine; complained of a pain in right side (more severe in some parts than in others), which commenced at 1 with shiverings, disappeared in two hours, and returned at precisely the same hour next day. Five doses of ten centigrams each removed the pain. About six weeks later there was a relapse, the pain this time being located in the stomach. One grain in five doses, one dose every two hours, removed the pain, but it returned the third day. The same treatment then removed it permanently. (5) Young lady, 18, had periodical facial neuralgia; cured by same treatment., Fornias adds this case: His niece, 5, living in Havana, had been suffering from a continued fever with periodical midday exacerbations, which later on assumed an intermittent form. She had been saturated with Quinine, and complained at the time of malaise, lassitude, headache, gastric intolerance, &c., when she was seen by Doctor Govantes, who prescribed an extract of Parthen. hyst., three doses a day, each the size of a pea. In four or five days she was free from fever, and made a quick recovery. In the proving the pains were sudden, congestive, out-pushing. A large number were experienced in the head and ears, and singing and fulness in the ears was among them, which points to its antidotal action towards Quinine. The symptoms were after getting up and going about.

 It antidotes Quinine. сompare: In spleen affections, Helianth., сeanoth. In malaise and periodic neuralgia, Malar. off., сhi., сedr.

 Feels dull and stupid. Difficult to fix attention. Malaise, apathy, lassitude (D). Indifference (D).

 Vertigo; while sitting, with heat of face and blurred vision. Heaviness and dulness of head. Full feeling, especially in vertex, pressing from within. Stitching pain in left temple, of short duration. Aching pain at left supra-orbital foramen. Head heavy, brain feels loose; after moving about and washing face. Sudden darting pains in right, then left, frontal eminence,.
 Eyes heavy; drowsy. Aching in eyeballs. Must look intently to see the words; when writing the letters seem pale and eyes ache. Aching over eyes; wants to close them.
 Ringing in ears,.
 Pain at root of nose and in nose; in all bones of nose,.
 Bursting, pain in right malar bone. Seems as if blood would burst through face. Aching pains run up from above left eye-tooth to eye and over face; occurs by starts and stops.

 Upper teeth feel on edge; pricking pains in sockets. Head thick, heavy. Sharp aching twinges in upper molars. Upper incisors tender at sockets when biting. Sharp pain in left upper and lower molars. Teeth feel too long. Tingling in tip of tongue. Profuse, very fluid, salivation.

 Goneness in epigastrium; hunger. Irrepressible, tasteless eructations. Eructations tasting of the drug. Hard lumps at epigastrium. Heat and weight in stomach.
 Severe pain in left hypochondrium, with tertian fever (cured with Parthenia). Spleen painful to pressure; pain in right side, worse in some parts than in others, with shiverings 1 daily (cured with Parthenia). Loud rumbling in bowels; about navel. Slight colicky pains at navel. - сolic deep in pelvis; pains run down backs of thighs to knees. Sore.
 Stabbing pain runs up rectum after passing flatus. No desire at usual time (10 p.m), 10.30 mushy stool.

 Kidneys enlarged and congested (D). Increased urine.
 Given to pregnant women for febrile conditions, it has caused abortion and premature delivery (D). Given in a case of subacute tuberculosis, it restored the menses, which had been absent since the illness commenced. Great increase of milk in breasts of nursing women cured with Parthenia of intermittent fever.

 Slow, irregular (Cheyne-Stokes) breathing (D).

 Excitation of heart-beats; or slow heart (D). Progressive slowness of pulse, followed by syncope, cardiac paralysis, and death (D). Pulse slow, soft, compressible.

 Hands feel numb, especially their dorsa.
 Pains run from pelvis down backs of thighs to knees. Marked diminution of reflex in hips and extinction of voluntary movements (D).

 Tremors (D). Muscular relaxation; anaesthesia (D). - сoagulation of blood retarded (D). The alkaloid is very rapidly absorbed and eliminated. General depression and lassitude.

 Restless night, wakes at 3 and 4 p.m, then dozes and dreams till 7.30. Increased stupor; desire to be quiet (D).

 Rise and fall of temperature, shivering, diminished perspiration (D).

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