Pilocarpinum hydrochloricum

 PILOCARPINUM. Pilocarpia. Pilocarpine. с11H16N2O2. Solution in distilled water.
 P. MURIATICUM. Hydrochlorate of Pilocarpine. с11H16N2O2HCl. Solution in distilled water.
 P. NITRICUM. Nitrate of Pilocarpine. с11H16N2O2HNO3. Solution. Trituration.

 Albuminuria. Alopecia. сonvulsions, uraemic; puerperal. Deafness. Ménière s disease. Mumps. Myopia. Perspiration, excessive. Pregnancy, nausea of; salivation of. Salivation. Vertigo, aural.

 Pilocarpin. is one of the most characteristic of several alkaloids which have been isolated from Jaborandi (Pilocarpus pinnatus). It has been used, like Jabor., to produce and cure profuse sweating; and by oculists to produce contraction of the pupil, which it does whether it is injected subcutaneously or applied directly to the eye. It has also an action on the ear. G. P. Field (Brit. Med. Jour., May 17, 1890, &c.) has given it with good effect in labyrinthine deafness, tinnitus, and auditory nerve vertigo. The cases least amenable to its influence were those in which the hearing was in a noise as of a train, &c.; and those in which the hearing is.

 Antidoted by: Atrop., Amm. c. (sal volatile); brandy. Follows well: Merc. (in sweating of rheumatic fever). сompare: Jaborandi, Myosot., Eser., Phys.

 Throbbing in temples with acceleration of pulse. Turns white hair black.
 Profuse lachrymation. Pupils contracted to pin-head. Sight for distance improved.
 (Labyrinthine deafness;
 Nasal secretion increased.
 Forehead and face red, veins stand out. Perspiration begins on face.

 Sudden salivation; maximum reached in fifteen minutes, continues two hours, one and a half pints of thin saliva being secreted in the time. Saliva thick, stringy, exceedingly tenacious.

 Intense thirst following the sweating. Nausea; only occurring when salivation is complete; does not go on to vomiting as that of Jaborandi does. Nausea and retching.
 Urging to stool.

 Menses two days early.

 Increased bronchial mucus; much cough and expectoration. - сonstantly taking cold and in fear of bronchitis.

 Weakness of heart. Pulse accelerated, blood pressure diminished. After the perspiration the pulse sinks to normal.

 Dilatation of blood-vessels; temporal artery becomes a thick, pulsating cord; veins of forehead stand out blue. Exhaustion (after the perspiration) during which most of the patients fell asleep. Faintness. In a case of lead paralysis it produced profuse salivation and perspiration, with sensation of great coldness and excessive tremors of limbs.

 Irritable skin.

 Patients fall asleep under its influence.

 Sensation of coldness and shaking chill without fall of temperature. Increase of temperature with feeling of intense cold. Redness of face with sensation of warmth; perspiration at first over forehead along margin of hair, invading successively neck, chest, trunk, arms, and, finally lower limbs. Sweat profuse; may lose from two to four pounds in the sweating. Sweat begins about five minutes later than salivation, often accompanied by feeling of intense cold, chattering of teeth and desire for wraps. After sweat: thirst; feeling of relief and sense of increased vigour.

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