Osmium metallicum

 Osmium, an element. Osmium tetroxide (Osmic acid), OsO4.
 Preparation: Dilutions, with absolutely pure water, of Osmic acid; or triturations of the precipitated metal.

 Morose mood. Irritable, at times even angry. He gets very impatient on account of an itching, on going to bed, which prevents sleep. Misplacement of words in the same phrase (1st dec. Disinclination for every work; (after two hours). Thoughts of accidents having happened to others, by a blow, a fall, or being dashed to pieces; gradually these thoughts grow upon him, as if he were to do the same injuries to other (after several weeks). Inward weakness; thinks he will have to give up practice on account of mental weakness, in the evening, when riding out.

 Frightful headache, depriving him of sleep. Terrible headache above and under the eyes, on one side, tearing towards the ear; worse under the eyebrows; the eye waters and is weak (a similar effect from others influences, f. i., Oxide of kakodyl). Dull headache, like a band round the head above the ears; after the second dose, the dull headache extends from the base of brain into the jaws (third day); at night, dull aching at base of skull and in jaws (fourth day). Intense dulness of the head, with heat in it (soon after 1st dec. Dullness of the head, with pressure and heaviness, especially in the left frontal eminence. Dull head all day (second day). Head feels dull and full (after two hours).
 Heaviness of the head. Muddled head (fifth day). Peculiar feeling in the head (soon after olfaction). Forehead. Headache in the right upper side of the forehead, a tearing to and fro, deep in; at the same time similar pains in the bones of the limbs, deep in, the evening (first day, 1st dec. Pressing headache in the localities of the organs of ideality (after olfaction). Pressing headache in the forehead, soon followed by ulcerative pain in the left leg and gluteal muscles, at 9 (five minutes after twice repeated olfaction). Great pain in the upper right side of forehead (soon after olfaction). сompressive pain in the forehead and temples. Temple. Headache, principally in the temples, with pain in the larynx, and hoarseness. Severe pressing pain in the left petrous bone, upwards and backwards of the ear (after trituration). Vertex and Parietal. All the afternoon had fullness and aching at the upper and back part of the head, indoors and out; worse by throwing the head back (second day). Occipital headache continued (sixth day). External Head. Falling out of hair is increased and continues (twelfth day, after 1st dec.
 Eye.
 Immediately struck with a sharp pain, he shut the eye and drew back. In ten minutes he came to my office. The lids were spasmodically closed, light very distressing, and pain in the globe severe. The conjunctiva and sclera were intensely injected, an lachrymation profuse. Pupil of natural size and activity.
 Slight dim, viz., 1/3, and reads only №3 of Jaeger at ten inches. All objects look dim. This dimness is not the effect of lachrymation, because wiping away the tears does not better the vision. Accommodation perfect. There are no muscae nor phosphene; the visual field normal. вy the ophthalmoscope, both the inverted and upright image, no material change discovered. The media clear, the optic nerve pink, but not unlike the other eye. The external inflammatory symptoms continued for one day, and then the eye resumed its normal condition, both in appearance and function. Extremely violent pains in the eyes. Violent pain around the left eye, as if externally on the bone (half an hour after 1st cent). вurning pain in the eyes, from going into an atmosphere containing vapors of Osmium. Sensation as if the axis of vision was moved back and forth a short distance, without moving the eyes; with closed eyes, in the evening (first day, 1st dec.). вurning sensation in the eyes, with profuse lachrymation.
 Extremely violent burning pain in the eyes, with very copious lachrymation. Extremely small quantities of the vapor act violently on the eyes and lungs. Lid. Muscular twitchings, both felt and seen, in the levator of the right upper lid, relieved by rubbing, but always returning and lasting two hours, during the morning (second day). Violent itching in left inner canthus; irresistible desire to rub it (second day, after 1st cent.
 Lachrymation. Lachrymation, aggravated by fixing the eyes upon any object. сonjunctiva and вall. вurning sensation in the conjunctiva. Pressive pain in the eyeballs. Vision. Acuteness of vision diminished, so that large objects, somewhat distant seem enveloped in a fog, and cannot be distinctly recognized. Dimness of vision, especially of the right eye, that cannot be removed by wiping; it seems as though a mist were before the eye, or the room were full of smoke. Decrease if sight; could just tell night from day, but could not discern the large letters on a title- plate; this remarkable affection of the sight lasted, each time, after smelling вioxide of Osmium, for three or four days. When attempting to read, letters run together, so that he cannot distinguish them. The candlelight is surrounded by a bluish-green circle, the outer margin of which is bright red; if the light is removed to the distance of ten or fifteen paces from the eyes the circle disappears, an the flame seems indistinct, as if enveloped by a cloud of dust or smoke. сandlelight surrounded by a bluish- green circle, bordered by an ashy-gray margin, becoming larger as the light was removed. The flame of the candle seemed surrounded by a green circle, bordered by a red margin, which was larger or smaller, according to the distance from the light. сandlelight surrounded by a yellowish circle; at the distance of about ten feet it had a diameter of three inches. In the evening, a very large rainbow-hued ring around the flame of every candle, whenever he is exposed to an atmosphere smelling of Osmium, even slightly. The flame of the lamp, in the evening, seemed much larger and more confused than natural.
 Ear.
 Earache, first in the right, then in the left ear, in the evening (first day, 1st cent. Ringing in the right ear (half an hour after 1st dec.), with pain (immediately after trituration).
 Nose.
 Coryza. сonstant discharge from the nose. сonstant running from the nose, with a sensation as if the nose were full. Secretion from the nose. Sneezing. Frequent sneezing, with increased secretion of mucus in the nose. Frequent ineffectual efforts to sneeze. From the posterior nares, lumps of phlegm easily loosened. Sensation of fullness in the nose, as if coryza would come on. Prickling sensation in the nose, as if coryza would come on. Prickling irritation in the nose, throat, oesophagus, an trachea, as if he had been burnt with hot water. Very violent burning irritation in the nose. Sensation in the nose as though blood rushed into it from the head. Irritation in the Schneiderian membrane, like that caused by snuff. Nose and larynx very sensitive to cold air. Smell. The sense of smell is diminished (second day). Sense of smell and taste blunted. Smell similar to сhlorine. The stinging odor of the acid remained for a long time in the nose, and afterwards changed to a sensation like that after one has received a blow upon the nose (odor of blood).
 Face.
 Dull aching in jaws an at base of brain, at night (fourth day).
 Cold jerks in the left upper jaw and front teeth, after olfaction. Pain in the muscles of chewing, after eating wheat bread (from two to three hours).

 Teeth and Gums. The teeth creak, more than usual when rubbing them with the finger (1st dec. The pain in the right upper tooth returned, but was drawing, and was relieved by sucking the tooth with the tongue (third day). Jerking pain in a right upper hollow tooth, very painful, frequently preventing speech (have had a pain in this back tooth before, but it was of a very different character). вroad swelling above the root of an upper left incisor, with pain and numbness; suddenly, after eating pears; disappeared after Silicea (fourteenth day, after 1st dec. Tongue. There was a red stripe on the middle of the tongue, that pined as if sore; the edges of the tongue were rough and covered with small pimples; the tongue was sensitive to the slightest touch, when eating an drinking. Tongue much coated; coffee tastes badly (third day, after 1st dec. General Mouth.
 Mouth sticky and pasty, as after a long illness (after a few hours). Saliva. Increased secretion of saliva, with frequent need of spitting. сopious salivation, with constant expectoration of mucus, with retching, without inclination to vomit. сopious salivation. Salivation. Taste. Taste blunted. Taste of blood in the mouth. Metallic taste (after two hours). Tobacco does not taste as usual, it causes a scraping in the throat; cigars cannot be smoked, because they provoke cough an aggravate the rawness in the larynx.
 Throat.
 Burning irritation in the pharynx. Sensation of increased warmth along the oesophagus, in the chest (immediately).
 Voice. Hoarseness, with pain in the larynx, for eight weeks; she was hoarse when talking, but particularly when sighing, so much so, that she could not sing at all; the hoarseness was much worse each time after going into the open air (riding out or walking), as soon as she came home. Hoarseness.
 Paroxysms of convulsive coughing. Frequent cough. сough, with sensation of constriction in the air-passages. сough, only in the morning (after three days). сough, on rising violent short bursts of cough, without expectoration (fourteenth day after 1st dec.
 Cough short, dry accompanied and followed by pain in the larynx and trachea, extending to the middle of the sternum, as if raw and sore; very violent, as if the mucous membrane would be torn off with every paroxysm of cough. сough dry, racking, difficult to loosen. Dry spasmodic cough. Hacking cough, relieved by deep inspiration. сonstant hacking cough. Hacking cough an irritation in the larynx, aggravated by motion, in the open air. сough, with secretion of colorless mucus (after several hours). After a cold, while nursing a sick child, and losing sleep at night, slight cough with pain in the larynx, she had also some coryza, but continued to take Osmium 6th cent. The tongue became very sore, the pains in the larynx very severe; she was taken with hoarseness; she was afraid she would get the croup, and took Spongia and Hepar, which relieved somewhat. After coryza, the cough returned during the day, very severe and disturbing sleep until midnight; a slight but irresistible tickling irritation in the larynx, causing short bursts of cough, increasing in violence; after repeated sneezing something is loosened, like a little round lump, which he is compelled to swallow (fifth day).
 Hawking of mucus frequently accompanied by attempts to vomit.
 Incessant expectoration of mucus, causing inclination to vomit.

 Abdomen.
 Rumbling and gurgling in the abdomen, as if in the intestines air were mixed with water, indeed one can feel the bubbles of air passing through the intestines, though there is no pain. Rumbling and moving about in the abdomen (after a few hours). Slight griping in the bowels, at night (second day). Abdomen very sensitive, and distended all the afternoon (fourth day); again troubled with distension, all the afternoon and evening (fifth day); bowels distended, in the afternoon (sixth day). Sensation like great weakness in both groins towards the spermatic cords (soon). Pressure on both inguinal rings (sixth day).
 Rectum and Stool.
 Urging to stool, but only passage of flatus, in the afternoon (second day after 1st dec. Stool very hard, then soft, preceded by violent urging, followed by frightful burning in the anus preventing sleep, with desire for stool after drinking coffee), (1st cent. Diarrhoea-like, bloody, as much as two or three centimeters every time (did not suffer from hemorrhoids).
 Evacuation soft, almost pasty, though formed thin, otherwise normal, at 9 , following a normal stool, at 10 p.m (first day). Mushy stools in the morning, afternoon, and evening (1st dec. In the morning, first hard, then thin soft stool, of a striking orange-yellow color (after olfaction, third day). The bowels were not moved till 4 ; the evacuation was passed hastily, with burning at the anus; it was bilious and partly fluid (second day); no evacuation to-day, only a small lump, like a marble, passed, after trying very hard to relieve myself (fourth day); no evacuation to-day until 10 , it was dry and full of air (sixth day); bowels relieved at 10 p.m, it was small in volume and quantity (seventh day); the bowels remain costive (eleventh day). The bowels are confined, but move daily.
 Evacuation delayed, small and constipated (fifth day).

 Appetite. Loss of appetite; for dinner (sixth day). Great aversion to his coffee and tobacco, even their odor was disgusting. Eructations. Incessant, extremely distressing eructations of the odor and taste of the drug, with great nausea, so that he thought he would vomit every moment, which, however, he did not; this was accompanied by much spitting of the saliva, which constantly accumulated in the mouth, and which was very watery (after twenty minutes). Empty eructations, at first without taste, afterwards having the taste and odor of the acid, relieving the nausea (soon). Eructations of the odor of radish (after a few hours). Nausea and Vomiting. Sensation of qualmishness and discomfort, in the abdomen below the navel, with a feeling of weakness (after a few hours). Feeling of qualmishness in the pit of the stomach, while riding, in the open air (second day). Qualmishness and extreme discomfort, with dull pain and heaviness in the pit of the stomach, after eating.
 Nausea, without accumulation of water in the mouth, and without retching. Nausea, with accumulation of water in the mouth; obliging frequent spitting (immediately). Frequent attacks of nausea without any cause (after several days). Nausea, without vomiting. Vomiting of much watery mucus, of the odor and taste of the acid, with numerous blackish-green flakes of mucus, looking like the deposit that the acid causes when brought in contact with organic substances; vomiting paroxysmal, at first of water, afterwards of yellowish and tenacious substances; after vomiting eructations of gas of the odor and taste of the acid, with continued salivation (after half an hour). General Stomach.
 Distension of stomach and bowels, with difficult passage of flatus, in the evening (third day). All the evening had distension of stomach and abdomen, although the dinner was only plain roasted mutton and potatoes (first day). At 6 , weakness of stomach, almost amounting to nausea, and aversion to cocoa, usually so well relished; this, by-the-by, occurred during the digestion of meat pudding, and requires a glass of brandy an water, at 10.30, to set matters right (after three hours and a half). All day yesterday and to-day there has been uneasiness in the stomach, increasing to anxiety and contraction; worse after food, and much aggravated by stimulants (eight day). сonstrictive pain in the stomach, in the forenoon (seventh day). вefore dinner (which I take at 12.30), felt contractive pain and weight in epigastrium; this is often attended by a feeling in the stomach as if I has swallowed a lot of stones from a newly laid road (sixth day). During the proving my digestion suffered a good deal, and during about nine or ten days, I felt no attraction to the pleasures of Venus, although at all over times very easily excited thereto. My suppressed report ran thus: Venereal appetite suppressed for eight or ten days; the conjugal act when performed was done by a sheer act of volition, and the usual thrill in ejaculation was absent (in a letter to the Editor, Aug.
 3rd, 1877 ).

 Urine. Urine very albuminous. In the evening perceived the urine to be strongly scented, somewhat like violets, very highly colored, and apparently full of bile (fifth and sixth days).
 Urine brown an scanty all day (second day); this morning the urine was scanty, and strongly scented, but not so dark as before (third day); scanty and dark-colored urine (fourth day); now begins to be more free and less colored (eleventh day). Much bright-red sediment in the urine, in part deposited on the bottom, in part adhering to the sides of the vessels.
 Sexual organs.
 Male. Pain in the spermatic cords, especially in the left (the same which he had after phosphoric acid), (soon after triturating; the same again after 1st dec. Pain in the spermatic cords, extending into the testicles, with inflammatory swelling of the right inguinal glands, as large as a pigeon’s egg; this lasted ten days. Glans penis reddened, on the left side; during coition a longer lasting emission of semen (1st dec. Throbbing, stinging, pricking, pinching pain on the left side of the glans penis (after trituration). Violent yet undefined pain at the tip of the glans penis and in the foreskin (1st cent. Pain in the right testicle (immediately after olfaction). Pain in the testicles, so that he could not sleep the whole night. Very hard erections (sixth and following days after 1st dec. Very hard erections; frequently soon after midnight, always on awaking in the morning, without exception, either before or with it; later, they continue longer, even after rising; moderate sexual desire (tenth and eleventh days, after 1st dec). Erections every morning, earlier and harder.

 Larynx, Trachea, and вronchi. Small lumps of phlegm easily loosened from the larynx. The mucus hangs in the larynx like a thread, irritates to hawking and cough, causing retching and almost vomiting; after sneezing it is loosened very easily (eleventh day after 1st dec. With a slight cough and coryza a very severe pain in the larynx; it pains her to talk, every word she speak hurts her. Sore pain in the larynx. вurning irritation in the larynx and trachea. Irritation in the larynx, with hacking cough. Tickling in the larynx,. Scraping in the larynx, provoking cough. Slight rawness in the larynx (eleventh day);increasing until the thirteenth day, when it was a very severe laryngeal catarrh, the voice hoarse, weak, and low, and almost extinct; lay in bed all the morning, and took three doses of Mercurius sol. and two of вell which carried off the attack, in the afternoon. I am not positive that the laryngeal affection was medicinal, but I am very much inclined to think it was. Scraped, raw sensation, and prickling in the larynx, not provoking cough. Scraped, raw sensation in the epiglottis.
 Sensation in the larynx, causing frequent hawking. Profuse secretion of mucus in the air-passages, with constant inclination to cough. Tedious secretion of phlegm from the air-passages (after inhaling vapors of Osmium). Very extensive bronchitis.
 Respiration. Difficult respiration. Difficult respiration, which was almost asphyxia, with dry skin, and temperature of 40.6 0 с.
 Difficult whistling respiration. Difficult respiration, with dyspnoea.
 Chest.
 Moist rales in the chest and larynx on breathing. Pneumonia very peculiar an extremely obstinate; possessing a singular motility, occupying at one time a certain portion of the lung, at another time changing its place. Autopsy showed the whole left lung in the third stage of gray hepatization; in the other lung, red hepatization; there were also found indications of approaching gangrenous dissolution; the bronchial glands enlarged, red and soft; the kidneys showed the second stage of вright’s disease; in the stomach were large ecchymosed spots. Air, containing vapors of Osmium, affects the lungs when inhaled. Oppression of the chest. Oppression of the chest, with difficult respiration, as if the lungs were collapsed and they could not get air enough, relieved by deep inspiration. Tightness of the chest; dread of breathing; one can feel the air entering the bronchial tubes by the sore pain it causes. Pain near the left lower rib, about a quarter of a circle towards the front; a dull stitch (immediately after olfaction). Rawness in the chest provokes hawking and hacking cough. Sensation of dryness in the chest. Pain beneath the sternum on coughing, extending to both sides of the chest, with a burning soreness, as if everything were raw; after coughing a long time some lumps of yellow tenacious mucus were loosened.

 Pulse 90, when I am well it is 72 (sixth day); 80 (seventh day).
 Pulse 80 at 11 p.m (fourth day).

 Pains in the back. A peculiar pressing pain in the back, extending from the scapula to the sacral region, aggravated by motion and by cough. Pain in the lumbar region. Pressive pain in the sacral region.
 Extremities.
 The limbs feel as heavy as lead, with weariness and heaviness in them, especially in the knees, was unable to stand long (after two hours).
 Superior Extremities.
 Shoulder and Arm. Pulsating, dull stinging on the inner side of right shoulder-joint (after olfaction). Severe pinching pain in the left upper arm, a hand’s breadth above the elbow, inwardly and on the inner posterior side; often repeated and very severe, for fifteen minutes (soon). Sensitive pain in the middle of the left humerus; soon after in the fingers of the left hand (two hours after olfaction). Elbow. Violent bone-pain in the left elbow (immediately after olfaction). Forearm. Violent pinching in the bones of the right forearm (after 1st cent. Drawing on the inside of the right forearm (after 1st cent. Drawing on the inside of the right forearm (after olfaction). Dull weary pain deeply seated in the left radius, aggravated by lifting anything or by allowing the hand to hang down, lasting three days, gradually disappearing; on the third day, the pain extended to the same place in the right forearm but was much less severe.

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