Coca

 Erythroxylon coca, Lam.
 Natural order: Lineae (suborder, Erythroxyleae).
 Preparation: Tincture of leaves.

 Mind.
 Emotional.
 Brain excited., Gentle excitement, followed by wakefulness (from weak tea). Pleasant excitement, with following sleeplessness. A peculiar aberration of the intellectual faculties, characterized by hallucinations. Excited fantasies, wonderful visions, now indescribably beautiful and wonderful forms, now frightful images.
 Passion for solitude. Desire to isolate one’s self. In the evening, while writing, the child groans, with irregular or difficult breathing. Lively mood, inclination for mental work (first day).
 After he felt perfectly healthy again, his spirits remained excellent, in spite of depressing circumstances. Felt very much elated. Felt something like expectation. Mental depression eighth day). Depressed and weary in the evening (fifth day). Sadness.
 The sadness and dejection of mind of the Indians in the Peruvian Andes ought not to be ascribed to the use of сoca; on the contrary, the сoca is the only thing to rouse them, at times, out of their stupidity. When lifting anything, fear lest I should let it fall, in the morning (sixteenth day). Great apprehension (seventh day). Great apprehension, with violent palpitation (ninth day). Very irritable (fifth day).
 Woke this morning early, feeling ill-humored because the light came in strongly through the blind, which I had to darken.
 Afterwards dreamed that I was relating some joke to some friends, at which we all laughed; I actually laughed in my sleep, but on being woke immediately, could only recollect part of the joke (seventeenth day).
 Very morose mood. General obtuseness of feeling (chronic symptom of chewers). They turn phlegmatic while under the influence of the leaves; the most important, even dangerous, event cannot frighten them out of their state of rest. During the periods of enjoyment, the phlegm of the chewer is marvellous; no degree of urgency or entreaty will move him; under the influence of the сoca the chewer is headless of the thunderstorm which threatens to drown him where he lies, or the roar of approaching wild beasts, or of the smoking fire which creeps along the grass, and is about to suffocate or scorch him in his lair.
 Mood changeable, mostly very morose; irresolute, false, and deceitful characters. The disposition is very changeable; they are mostly very wayward, but notwithstanding the sad condition, they yield on the first opportunity to an unbridled passion for brandy.
 Intellectual. сan, while in a condition of mental excitement, write quite freely and correctly. From 7 to 10 p.m, felt like work; after that, a dull frontal headache, lasting the rest of the day (second day). Aversion to concentration of thought upon any one thing. Not in humor to study or read journals; lazy and sleepy (first day, 9 P.M). Dull apathetic condition. вrain feels so muddled that he cannot read French journals understandingly; must look in dictionary for words usually familiar to him (fourth day). Slow in finding the words to express himself at times (first day). Mind much clearer; spirits much better.

 Head.
 General Head.
 Head very clear.
 Headache. Headache is excited from sleeping near heaps of dried leaves. Headache followed tablespoonful doses in two hours from first dose, abating somewhat before second dose, present all the afternoon, left at evening (fourth day). Headache, leaving after eating, returning in three hours and a half, and leaving at sunset (third day). Headache began at 10 p.m, relieved by walking in open air, but returned upon going indoors (fifth day).
 (In afternoon (indoors), headache; afterwards, soon after commencing walk in open air, headache in upper part of forehead for a short time), from heat of weather (one hundred and fifty- third day). Headache in the afternoon (as if catarrhal), with cold feet and unusual urging to stool (second day). Headache and giddiness. Headache increasing (7 P.M)., especially over right eye; burning of the eyes (seventh day). Headache, with chilliness (third day). Frequent headache. About 1 (indoors), slight headache; afterwards, when walking in open air (it was raining), pain sometimes in right temple, sometimes in forehead; lessened or removed by standing still; after coming indoors, dull pain in forehead, sometimes in right half, sometimes left, sometimes all over forehead), (one hundred and thirty eighth day). Rather severe headache (after two hours). In afternoon, dull headache; afterwards, when walking in open air (it was a warm day), frontal headache, worse at each step, not lasting long, from the hot weather), one hundred and fifty-second day). Very slight dull headache after rising (twenty-eighth day). Fullness of the head, like after drinking wine, 4 (first day).
 Forehead.
 Fullness in forehead, as if the brain were heavier in that region (first days). Fullness of forehead; dull feeling over the whole brain; slight shooting pains in right temple; sensation of tension over forehead, as if an india-rubber band were stretched over it (seventh day). Fullness and pressive pain in forehead, although he sits near the open window, with aggravation towards 9 (sixth day). Frontal fullness of the head; the letters swim together on reading; eyes feel heavy (fourth day). Severe pain deep in the left side of the forehead, like a pressing asunder, on coughing or on pressing at stool (fourth day). Severe headache just above the eyes (seventh day). Frontal headache, next above the eyebrows, not constant, increased by elevating the head and turning the eyes up.
 Dull frontal headache, which vanished with the setting of the sun, followed by a state of mental exhilaration. Dull frontal headache, relieved somewhat upon walking a mile, returning upon going indoors, with a heavy feeling of eyelids, 9 p.m (after one hour). Slight pressive pain in the forehead (fourth day).
 Sensation as if a band was stretched over forehead, from temple to temple (ninth day).
 Temples.
 (Pain in both temples when walking quickly in the hot sun.
 Lessened by standing still; after coming indoors, a pain for a minute or so in coronal region; after this had gone, pain in right temple on shaking head from side to side; afterwards, when lying down, pain in anterior part of top of head, and also other parts not particularly noticed; these pains soon went off), 12.50 (one hundred and thirty-fifth day); from the heat of the weather. Sudden pain about region of left temple, quickly passing off; 10.45 p.m the same; 9.30 (sixth day). Dull pain over left temple (first day).
 Pressing pains in right temple as if a nail was driven in, and the old dull, pressing, frontal headache again, especially over right eye (nineteenth day). Slight pressing pains in left temple, with dulness of head, half an hour after taking a dose (fourth day).
 Headache in the morning in the right temple, sharp on first rising, and all day, whenever looking up; the pain darts from the temple in a straight line to the top of the head and leaves a sore feeling behind; hurts through this same place when coughing (tenth and eleventh days).
 Parietals.
 When blowing nose, a sudden pain extending over anterior portion of right side of head, soon passing off, 9.50 (second day).
 Rather painful pressure on sides of head. Pressive headache on the right side and in the occiput, and somewhat weaker on the right side of the forehead, with chilliness and vertigo (eighteenth day). Throbbings in right side of head for a minute or so at 3.15 (fifteenth day). Throbbing in right side of head for a minute or two at 9 (TENTH DAY).
 Occiput.
 Pain in lowest part of occiput when yawning; the pain sometimes prevented the completion of the yawn (one hundred and sixth day).
 (About 6.10 , when running in open air, pain in occiput felt at every step; afterwards, pain there when walking for a minute or so), from hot weather (one hundred and fifty-ninth day).
 Headache in the occiput (nineteenth day). After waking from the midnight nap, the phantasms had disappeared, but on attempting to read, drawings commenced in the occiput, and extended to the temples (this condition lasted the whole afternoon), (fourth day). Pressure in the occiput (second day). Headache in fresh air changed to the occiput, as if it were held from ear to ear in a vice (first day).
 Eye.
 Eyes hollow, surrounded by deep violet-brown circles. He was chewing a leaf, in the corner, with staring eyes fixed upon the ground, automatic motion of the hands, and some dull groaning.
 Slight discharge of mucus from the right, and also somewhat from the left eye, during the day (second day after 10 drops). Pain in the eyes (fourth day). Pressure in the eyes (ten minutes after chewing the leaf), (ninth day). The eyes become very sensitive; reading cannot be endured long; some are troubled with slight headache, while others suffer from nausea and various disorders of the digestive apparatus, which may be compared with sea- sickness.
 Brow.
 A boring pain over the right eye. Sensation as if something were beating over the eyes (first day).
 Lids.
 Heaviness of eyelids (fifth day). Disposition on the part of the upper lids to fall, without being sleepy (ninth day).
 Lachrymal Apparatus.
 Lachrymation of the right eye, with slight redness of the conjunctiva and of the lids at the inner canthus, in the morning (after 10 drops).
 Pupil.
 Dilates the pupils; renders the eye intolerant of light (after large doses). Widens the pupils, and lessens the sensitiveness to light.
 Vision.
 Momentary blackness before the eyes (such as he had formerly experienced in summer heat, on going from sunlight into a dark room), on ascending stairs (three hours after 40 drops, eighth day). Great photophobia, with dilated pupils. Letters swim on the paper (after ten minutes). It is impossible to continue reading because the letters run together; fiery points float before the eyes downward (seventh day). It seems as if he were writing with two pens (after ten minutes). Flickering before the eyes (after ten minutes).
 Slight flickering black points before the eyes, towards 4 , while reading (eighth day). Fiery points flit before the eyes (after ten minutes). вright flash, like distant sheet-lightning, before eyes in the dark, at 11 (tenth day). Appearance of flames before the eyes, by paroxysms, similar to distant heat- lightning (after two hours). The appearance of flames before the eyes returns in the evening (second day). White spots before the eyes, so that the book from which I was reading seemed mottled white (fourth day). White spots, and glittering tortuous lines before the eyes, on going out after eating, with great weariness, lasting an hour (eighteenth day).
 Vision of colors and floating of sparks from before downward (soon after chewing the leaf, ninth day). Small bits of thread, about an inch long, which he has seen habitually hovering up and down before eyes, morning, in bed, or when looking into the light of the sun, or on the white wall of the room, paper, or white curtains, have become smaller and more indistinct (third day); more perceptible again (fourteenth day). After сamphor, instead of the floating threads, only one small dark spot the size of a lentil, floating before his eyes.
 Ear.
 Objective.
 Discovered accidentally, when washing, an excess of wax in right ear, easily removed by the towel, 7 p.m (seventy-sixth and ninety-second days).
 Subjective.
 Sensation of deafness in both ears, although everything is heard as distinctly as usual; still there is a constant sensation as though there were something in the ears which caused deafness (first day). Slight earache in right internal ear for a few minutes (in church), 7.20 (thirtieth day); (indoors), 1.
 (ninety-third day); an aching pain in right internal ear, and, to a less extent, in right mastoid process for a few seconds, then in ear, only for a few seconds more (sixty-fourth day). During loud reading in the room there was a sensation as though the tympana were pressed outward by the tones, or as though the tones first entered the ears through a thicker medium (second day).
 Hearing.
 Hearing painfully acute, during evening. Pulsation and dull roaring in both ears, in the forenoon (second day). Audible pulsation in both ears (first day). сracking in both ears, on empty swallowing (second day). Singing in the left ear, for several minutes (first day). Severe ringing in the ears; did not hear though one knocks three times at the door; when one speaks it seems as though the voice came from a great distance (seventh day). Violent ringing in the ears (first day). Violent roaring in the ears (after two hours).
 Nose.
 Sneezing several times (after three-quarters of an hour), (second day). Sneezed after rising, and in evening (twelfth day); later days occasionally indoors. Running of clear water from nose, and occasionally sneezing, without having properly a coryza as he usually has it; (weather warm and showery; the same next day), (nineteenth day). Flowing from the nose of clear water, occasional sneezing, feeling of soreness in left nostril, from 6 p.m till 5 , when in the draught, though not subject to colds (twenty-second day). сlear watery flow from nose, with small specks of blood on blowing nose (after inhalation).
 Increased nasal mucus (forty-first day), indoors (forty-second day), and out of doors, in morning; scarcely any excess in afternoon or evening; at one time, in morning, heat in nose (indoors), (forty-third day).
 In early morning, in bed, feeling of heat and irritation in right nostril, as from catarrh (eighty-fifth day); in whole nose, especially the left nostril, before and after rising (eighty- seventh day). In part of evening, indoors, nostrils feel rather hot internally, as after catching cold; nasal mucus less (forty- second day); later days, 6.40 p.m, heat and irritation in left nostril, as from a cold. In evening, irritation as if from taking cold; in the night, 9 o’clock, wakened by running from nose.
 During day, felt a soreness in nostrils, especially left; weather warm; after сamphor.
 Face.
 Paleness of the face. A kind of chlorosis develops; the bilious color first noticed gives place to a leaden hue.

 Confusion and Vertigo.
 Confusion of the head (twelfth day).
 Confusion of the head in the morning; relieved after washing and drinking coffee. сonfusion of brain, vertigo in forehead, disposition to sleep, want of appetite, low-spirited, about 5 or 6 indoors (second day). Vertigo (second day). Vertigo, whirling (eighteenth day). Vertigo on rapidly ascending steep steps, followed by diarrhoea once (after two hours). Vertigo while walking, with sensation. Vertigo, lasting half an hour, relieved by rest and by a glass of wine. Vertigo and dizziness (fifth day). Slight vertigo on moving in the open air; objects seem to turn, lasting one hour.
 Transient vertigo while sitting still, and once afterwards when rising from sitting (fifteen minutes after 40 drops, eighth day).
 Vertiginous feeling, preventing literary labor for about an hour.
 When the head was bent forwards in writing, transient feeling of giddiness, which seemed to proceed from occiput forwards, on left side; in five minutes another similar but slighter symptom, 7.30 (eighth day).

 Cheeks.
 Burning redness of cheeks, first left, then right, with white spots in the center of latter (sixty-fifth day). Pressive pain in the right malar bone (first day).
 Lips.
 Pale lips and gums, with green blunted teeth. About 10.45 p.m, slight burning in left upper lip, where the moustache grows (fifty-first day).
 Lower Jaw.
 Soreness in left lower jaw, just above-maxillary gland; worse on talking, and especially by eating solid food on that side (second day).
 Mouth.
 Greenish and stumpy teeth. Toothache in a hollow tooth (fourth day).
 Tongue.
 Tongue coated (twenty-first day). At tip of tongue, towards right side, an appearance of a vesicle that had broken, with a red circle around it; tongue there feels sore occasionally, when eating, touching it, and at other times; at first, the soreness was as if it had been scalded with hot tea; then more like a sore place (one hundred and first and one hundred and second days); well next day.
 Cocaine causes a numb feeling on the tongue.
 General Mouth.
 A swelling inside right lower lip; a few days after, a similar swelling inside left cheek, at upper part, nearly opposite first upper molar; sometimes rather painful when eating (sixtieth day), flattened on two sides (that next the cheek, and the opposite one), with a thin border; red, with a whitish patch at tip on the side next cavity of mouth, as if from pus; not so painful (sixty- third day); feels smaller, somewhat semicircular; apex more pointed; getting smaller (after sixty-four days); nearly gone (eighty-sixth day). Dryness of mouth on waking, about 6.45 p.m, gone in half an hour (sixty-third day); 7.30 p.m, again after a short sleep (on one occasion, with mouth open), eighty-ninth day); soon after waking (ninety-third day); immediately on waking (about 7 A.M)., mouth and lips, removed by breakfast (one hundred and tenth day); with disagreeable taste (one hundred and twenty- fourth day); still dry (one hundred and fifty-fourth day). сool feeling, verging on numbness, in the mucous membrane of the mouth and throat, similar to that after taking strong Aconite into the mouth. Still burning in mouth and throat, with increased thirst, set in. Fresh leaves burn in the mouth, like сantharides. Mouth and palate felt as if burnt with pepper, in morning. Swollen sensation in the arches of the palate, which made swallowing difficult, with at times tickling, causing cough, returned as in a former proving.
 Saliva.
 Increased flow of saliva, first of a bitterish, later of an aromatic taste (after chewing 1 drachm of the leaves).
 Throat.
 Sensation of dryness in the throat (after two hours).
 Soreness at back of throat on rising (thirteenth, nineteenth and, forty-first days). Scraping in the throat, with swollen uvula; this caused frequent hawking and expectoration of mucus (second day).
 Tickling at back of throat, on rising (forty-third day). Hawking up of small, transparent lumps of mucus, chiefly in morning (third day), third proving.
 Tonsils and Uvula.
 The uvula became long and red (from chewing the leaves).
 Pain on swallowing, as from soreness and swelling, in a small spot on the right side of the uvula (seventh day).
 Sensation of dryness in the throat; an unpleasant sensation on swallowing, as if swollen (second morning).
 Fauces and Pharynx.
 By a slight cough, loosened and swallowed some mucus from back of pharynx, 8.20 (ninety-first day). 3 o’clock p.m, dreamed he was trying to remove mucus from pharynx by hawking; on waking, in midst of dream, found himself doing so; could not succeed by coughing or hawking; voice hoarse; cold water did not affect the throat in any way (ninety-sixth day). Great dryness of fauces.
 Feeling as if some mucus were at back of pharynx, not removed by coughing or hawking, 11 (eighty-ninth day); still there, 8.27 (ninety-first day); gone, 8 (ninety-second day). At back of pharynx soreness and feeling of obstruction, not removed by coughing or hawking, with hoarseness, early morning (eighty-ninth day); after rising (eighty-ninth and ninetieth days), a slight cough loosened mucus; brought up a piece of green mucus (ninety- first day). Tickling or kind of soreness when talking (the same, one hundredth day); slight cough loosening mucus (ninety-first day); after rising (ninety-second day), not removed by coughing or hawking up, which however loosened; the cough caused soreness.
 Tickling at left side of pharynx when talking, 8.45 p.m (one hundred and thirty-sixth day). When talking, tickling at back of pharynx towards left side (ninetieth day).
 Swallowing.
 Difficulty in swallowing; the uvula is swollen, without special redness (second day).
 Pain on swallowing, with great swelling of the uvula, on waking in the morning (third day).

 Taste.
 Mouth out of taste, for two hours; 3.30 again, on rising; going off after drinking cold water (seventy-eighth day).
 Taste slimy (fourth day). Salt taste at tip of tongue, 4 ; about 9 , transient on anterior portion of right side (twenty-ninth day); during morning, again (thirtieth day). At tip of tongue, 2.45 and at 3.50 ; at 7.40 , over a larger portion of extremity, then on the right side of anterior part till about 9 ; eating a ginger-bread removed it awhile; again removed by supper, but again returned (forty-third day).
 Bitter taste on waking in morning, lasting only a short time; afterwards an unusual flow of water from nose. вitter taste in mouth, for a minute or so, about 7.15 p.m (tenth day). вitter taste on right half of tongue, for about a minute, at 12.45.
 (second day). вitter taste on right side of tongue, at 6.40.
 (fifteenth day). Insipid, grapy taste of the infusion. Water tastes burnt (twelfth day). вutter tastes like herring (ninth day).
 Appetite.
 Appetite increased for last few days (one hundred and thirty- second and one hundred and thirty-fifth days). Great appetite (after three hours). Sudden voracious appetite, especially for animal food, contrary to usual habit. Great hunger; dinner was eaten with appetite, even at 11 p.m, though less was eaten than on the preceding day, when he had no special hunger (sixth day).
 Morbid hunger, even to swallowing animal excrements; chronic symptom of chewers. Longing for food although the abdomen was somewhat distended in the epigastric region, as from an overloaded stomach (second day). Indians, after chewing all day, not eating any food, ate at night like hungry men, and sometimes at a single meal swallowed as much as would serve others two days. Appetite diminished; could not take his usual moderate quantum of food. Slightly diminished appetite Great diminution of the usually vigorous appetite; chewing the leaves suspended the sensation of hunger; though eating one-half less than usual, his weight did not diminish, nor the capacity to endure labor. Little appetite (fourth day). Very little appetite the first week, especially for meat, of which I was usually most fond (fifth day). Loss of appetite. Loss of appetite, with speedy satiety (twenty-first day). Want of appetite; weak digestion, and nervous irritation, with headache. Drinking the decoction at 3 or 4 o’clock it has invariably and totally deprived him of all appetite for dinner, and of his rest at night; under these circumstances he always passed the night in reading or writing; he felt no fatigue or hunger on the following morning. Retards approach of hunger (taken as tea). Enables the body to feed upon itself, without the hunger-pains and weakness usually accompanying prolonged abstinence from ordinary food. Very little need for nourishment, even during heavy work, with remarkable vigor. Did without food for full forty hours, and the next food taken was then exceedingly well digested.

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