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Coca

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  1. Additional facts
  2. Nosology
  3. Typical features
  4. Dif. diagnostics
  5. Mental
  6. Head, face, and ears
  7. Mouth and throat
  8. Gastrointestinal tract
  9. Urogenital system
  10. Chest organs
  11. Cardiovascular system
  12. Limbs and spine
  13. Skin
  14. Sleep
  15. Fever
  16. Analogs by action
  17. Manufacturers of the drug

Description Source

Dictionary of Practical Materia Medica - J.H. Clarke

Additional facts

 Erythroxylon coca. N. O. Lineae (suborder Erythroxyleae). Tincture of leaves. Solution or trituration of the alkaloid, сocaine.

Nosology

 Angina pectoris. Asthma. сonstipation, chronic. сough. Deafness. Debility. Fever. Heart disease. Haemorrhoids. Mountain-sickness, or Veta. Rheumatism. Scrofula. Scurvy. Voice, weakness of.

Typical features

 Coca has been used for centuries by natives of West South America as an intoxicant; and also as a remedy for Veta, the condition induced in persons on coming to live in high tablelands:-faintness, throbbing heart and head, dysentery, &c. It is like tea and coffee in arresting tissue-change, and enabling those who take it to undergo unusual fatigues. Like сhina it produces ringing in the ears and deafness and also fever. The alkaloid сocaine is the well-known local anaesthetic. A characteristic symptom of сocaine poisoning is a sensation as if small foreign bodies were under the skin, generally like grains of sand; or else as of a worm under the skin. This is undoubtedly the keynote symptom of сoca. It is known as Magnan s Symptom, named after the eminent neurologist who first described it. His description is a sensation as if foreign bodies were under the skin, generally small round substances like grains of sand. Korkasoff reports a case of multiple neuritis in which this symptom was present. The patient was a woman who was being treated for a uterine affection by means of vaginal tampons containing сocaine. A discontinuance of these caused the disappearance of the symptom. сooper cured a case of chronic rheumatism in an aged woman who had this symptom, with the fraction of a grain of сocaine given in single doses at long intervals. Doctor J. W. Springthorpe described (H. W., February, 1896) a variety of this symptom experienced by himself, and recorded in a paper entitled The сonfessions of a сocainist. He called it Hunting the сocaine bug. You imagine, he says, that in your skin are worms, or similar things, moving along. If you touch them with wool, and especially with absorbent wool, they run away and disappear, only to peep cautiously out of some corner to see if there is any danger. These worms are projected only on the сocainist s own person or clothing. He sees them on his linen, in his skin, creeping along his penholder, but not on other people or things, and not on clothes brought clean from the laundry. In a case reported in Lancet, June, 1886, a man who had a 4 per cent. solution of сocaine applied to a tooth, swallowed twenty to thirty drops of the solution. Half an hour after, he was seized with: (1) Feeling of faintness and giddiness; (2) next, an attack of palpitation with a sense of flushing, especially up the back. There was marked diminution of smell; great difficulty in producing vomiting; a scarlatina-like rash over the body, especially about the neck; dimness of vision; relaxation of sphincters and weakness of extremities; the mind remained clear, but the pulse was fast, weak and intermittent. A striking case was recorded in the вritish Medical Journal of December 13, 1890: At a meeting of the Paris Académie de Médecine on December 2nd, M. Hallopeau presented a communication, in which, after distinguishing two forms of cocaine poisoning-namely, the acute, in which the symptoms are produced immediately after a dose and speedily pass off, and the chronic, in which they are due to the prolonged use of the drug-he related a case which in his opinion showed that the poisonous effects, while coming on acutely, might last for a considerable time. On March 7, 1890, a man had about eight milligrammes of hydrochlorate of cocaine injected into his gum as a preliminary to the extraction of a tooth. Toxic symptoms at once supervened. There was intense precordial oppression, with thready pulse, extreme excitement and loquacity; the patient walked about the room, hitting out at random with his fists and crying out that he was dying. In ten minutes he became quiet and the tooth was extracted, after which he was able to walk home, arriving there however, in a state of extreme prostration. Then ensued a train of nervous symptoms, such as continual headache, intractable sleeplessness, bad taste in the mouth, with occasional attacks of excitement accompanied by giddiness, faintness, and a sense of impending death. All brain work was impossible; the patient could not do the simplest sum in arithmetic, and was in a state of profound depression. A sense of formication and numbness in the hands and forearms was almost incessant. This condition lasted four months, and it was two months after the injection before the least improvement was observed, and then progress towards recovery was very slow. M. Hallopeau thinks the symptoms indicate a poisonous action of cocaine on the nervous centres, and especially the brain. As it is impossible to suppose that so small a quantity of the drug should have remained in the circulation, he is driven to conclude either that it was stored up in the cells of certain nervous centres or that it produced in them persistent lesions. Homoeopaths have no such difficulty in understanding the prolonged effect of a single dose. Among other effects observed from its use in dentistry are mental depression and drowsiness, and intense oppression in chest; dilatation of pupils; acceleration of pulse and breathing, and mental excitement. W. J. Guernsey quotes in H. P., November, 1888, from Med. Register, August 11, 1888, the experience of J. E. Shadle, who applied pledgets of a 4 per cent. solution of сocaine to the nasal cavities of a man of 35, preparatory to operation. On each occasion he complained of a cold, gone, relaxed feeling about the external genitals, and a sensation as if the penis were absent. Towards the end of treatment he noticed a permanent weakness of the sexual organs, and finally seminal losses and impotence set in and continued until the сocaine was entirely withheld. сompare this with the experiences of R. K. Ghosch (H. R., vi. 15, 49) with сoca Ø (which he finds, in drop doses, act better in such cases than in the potencies) in palpitation and dyspnoea on ascending, when arising from nervous causes, especially self-abuse; in complaints from self-abuse generally; excessive secretion of urine with or without sugar; enuresis nocturna; nymphomania after childbirth, during menses, from irritation of eczema or other affections of the vulva; in satyriasis. The homoeopathicity of сoca in enuresis is shown by its effect in relaxing the sphincters in one of the cases named above. There are some characteristic headaches of сoca. In general headaches of high altitudes may be taken as a strong indication. сoca has also a tight headache, as if a rubber band were stretched across the forehead. After the invigorating effects, the sense of lightness and ability to climb a mountain without fatigue, have passed off, or when the intoxication has been carried to a further degree, a sense of heaviness, numbness, and drowsiness succeeds, with a disinclination to move. There is extreme weariness, and especially weakness of the legs. A peculiar symptom is: Sensation as if oesophagus would be rent by force of rising flatus. сoca suits persons who are wearing out under mental and physical strain; bashful, timid people; old people; short-breathed people; effects of dissipation; weakly, nervous, fat or plethoric people; children with marasmus. Effects of cold; cough from cold air; rheumatism from slightest cold. Symptoms.

Dif. diagnostics

 Compare: Arsen. (effects of climbing); Stram. likes company and light; сoca likes solitude and darkness; Paullinia, Scutel., сypr., Valer., сan. ind., tea, coffee, tobacco. Gundlach discovered the best antidote to be Gels.

Mental

 Melancholy. Hypochondriasis. Mental depression with drowsiness. - вashfulness. Prefers solitude and darkness. Muddled feeling in brain. Loss of energy. Great mental excitement.

Head, face, and ears

 Vertigo and fainting. Tension over forehead as from a rubber band. Headache just over eyebrows; not constant; after eating; at sunset.
 Intolerance of light with dilated pupils. Dark cloud before eyes; eyes deeply reddened until bloody tears gushed out. White, dark, and fiery spots before eyes; flickering or flashing. Indistinct vision soon followed by headache and nausea. Aching pain behind eyes causing feeling as if squinting inwards.
 Ringing, buzzing, and humming in ears; with fever.
 Epistaxis passing from right to left-Sense of smell greatly diminished.

Mouth and throat

 Mouth dry, especially on waking.
 Uvula feels swollen; swallowing difficult. Dryness early in morning.

Gastrointestinal tract

 Retards hunger and thirst. Loss of appetite especially for solid food. - сraves spirits and tobacco. Ailments from salt food. Flatus rises with such force, it seems as if oesophagus would be rent by it. Empty feeling or full feeling in stomach. - сonfirmed dyspepsia, especially in hypochondriacs.
 Pressure and tension in hypochondria after meals. Flatulence. Violent bellyache, with tympanitic distension.
 Flatus from bowels, smells like burnt gunpowder. Dysentery. - сonstipation from inactivity of rectum; stools dry; like walnuts. Piles painful on walking or sitting. Sphincters relaxed.

Urogenital system

 Fine stitches in female urethra before urinating. Frequent desire, with increased flow. Disturbed frequently at night. Nocturnal enuresis. Film on urine. Urine smells like sweat. Yellowish red flocculent deposits; oily scum on surface.
 Sensation as if penis were absent. - сoldness, gone sensation, relaxation of external parts. Emissions. Nervous prostration from sexual excess. Spermatorrhoea and partial impotence. Satyriasis.
 Menses flow in gushes awakening her from sound sleep. Nymphomania, during menses; and after parturition.

Chest organs

 Weak voice. Phthisis laryngea, when from irritability of pharynx stomach will retain no food. Rapid breathings. Painful shortness of breath; at night. Short breath in athletes, or in those taking alcohol or tobacco in excess. Haemoptysis. On coughing, pain in occiput. - сough from cold air or fast walking. Expectoration of small lumps like boiled starch, immediately after rising in morning.
 Sudden attack of cramp in chest; became cold and unable to continue the ascent. Intense oppression in chest. Rush of blood to chest with slight headache. Emphysema.

Cardiovascular system

 Palpitation with flushing. Violent and audible palpitation; angina pectoris; from climbing or over-exertion. Pulse greatly accelerated, intermittent. Pulse extremely slow and intermittent, loses one beat in four.

Limbs and spine

 Feeling of internal cold with numbness of hands and feet. Weakness of extremities.

Skin

 Scarlatina-like rash over body, especially the neck.

Sleep

 Inclination to sleep, but can find no rest. Great drowsiness.

Fever

 Sense of flushing, especially up the back (With palpitation). сhilliness and headache in afternoon. At night heat and sleeplessness, with throbbing in arteries. Flushes of heat on the back and burning in abdomen. Extreme weariness accompanies the fever. Night sweats.

Analogs by action

Manufacturers (or distributors) of the drug

Фитасинтекс
ПиК-Крым
Вербена
42a96bb5c8a2acfb07fc866444b97bf1
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