Compatibility «Hydrochlorothiazide+Dihydralazine+Reserpine» and «Telpres plus»

• Interactions Hydrochlorothiazide+Dihydralazine+Reserpine with Telpres plus

  • Dangerous interactions
    • ⓘ It should be used with caution with hypotensive drugs (their effect is potentiated, dose adjustment may be necessary), cardiac glycosides (hypokalemia and hypomagnesemia associated with the action of thiazide diuretics may increase the toxicity of digitalis), amiodarone (its use simultaneously with thiazide diuretics may lead to an increased risk of arrhythmias associated with hypokalemia), hypoglycemic oral medications (their effectiveness decreases, hyperglycemia may develop), corticosteroids, calcitonin (increase potassium excretion), NSAIDs (may weaken the diuretic and hypotensive effects of thiazides), non-depolarizing muscle relaxants (their effect may be enhanced), amantadine (clearance of amantadine may decrease with hydrochlorothiazide, which leads to an increase in plasma concentration of amantadine and possible toxicity), colestyramine (reduces absorption of hydrochlorothiazide), ethanol, barbiturates and narcotic analgesics, which enhance the effect of orthostatic hypotension.
    • ⓘ Previous therapy with high-dose diuretics, including furosemide (a 'loop' diuretic), may lead to a decrease in BCC and an increased risk of arterial hypotension at the beginning of telmisartan therapy.
  • Negative interactions
    • ⓘ Drugs: Hydrochlorothiazide+Dihydralazine+Reserpine and Telpres plus available common active substance : Hydrochlorothiazide. Pay attention to the dosage..
    • ⓘ Other antihypertensive drugs.
    • ⓘ It may be necessary to adjust the dose of simultaneously prescribed antihypertensive drugs.
    • ⓘ ARA II, such as telmisartan, reduces potassium loss caused by diuretics.
    • ⓘ Other antihypertensive agents.
    • ⓘ The effect of telmisartan on lowering blood pressure can be enhanced by simultaneous administration of other antihypertensive medications.
    • ⓘ Based on their pharmacological properties, it can be expected that the following drugs can enhance the antihypertensive effect of all antihypertensive agents, including telmisartan: baclofen, amifostin.
  • Unclear interactions
    • ⓘ Hydrochlorothiazide+Telmisartan + Hydrochlorothiazide analgin and citramon are used together in 8 preparations.
    • ⓘ Telmisartan + Hydrochlorothiazide analgin and citramon are used together in 8 preparations.
    • ⓘ 'Loop' and thiazide diuretics.
    • ⓘ Hydrochlorothiazide+Dihydralazine+Reserpine + Hydrochlorothiazide analgin and citramon are used together in Adelphane-Esidrex.
    • ⓘ Hydralazine + Hydrochlorothiazide analgin and citramon are used together in Adelphane-Esidrex.
    • ⓘ Reserpine + Hydrochlorothiazide analgin and citramon are used together in Adelphane-Esidrex, Triresid K, Sinepres.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 169,990,749 possible combinations of drugs and their components were found 412,526 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2024-11-07

Category - medicine