Compatibility «Dexamethasone» and «Glucophage»

• Interactions Dexamethasone with Glucophage

  • Dangerous interactions
    • ⓘ With simultaneous administration of GCS and antidiabetic drugs, it is necessary to monitor the condition of patients for deterioration of glycemic control, and with the abolition of GCS - for the development of signs of hypoglycemia.
  • Negative interactions
    • ⓘ Systemic and local GCS reduce glucose tolerance, increase the concentration of glucose in the blood, sometimes causing ketosis.
    • ⓘ In the treatment of GCS and after discontinuation of the latter, it is necessary to adjust the dose of the drug Glucophage under the control of blood glucose concentration.
    • ⓘ It weakens the hypoglycemic activity of insulin and oral antidiabetic agents, anticoagulant - coumarins, diuretic - diuretics, immunotropic - vaccinations (suppresses antibody formation).
    • ⓘ Drugs that affect glycemic control (thiazides and other diuretics, GCS, phenothiazines, thyroid preparations, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, BCC and isoniazid).
    • ⓘ Antidiabetic drugs (Insulin preparations, sulfonylurea derivatives (bucarban, butamide, etc.), biguanides (glybutide, etc.)) + Glucocorticoids, deoxycorticosterone, diuretics that remove potassium (dichlothiazide, etc.), corticotropin, cardiac glycosides => Weakening of the effect of antidiabetic drugs.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,027,037 possible combinations of drugs and their components were found 412,563 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-01-01

Category - medicine