Compatibility «Potassium iodide» and «Perindopril+Indapamide»

• Interactions Potassium iodide with Perindopril+Indapamide

  • Dangerous interactions
    • ⓘ The combination of perindopril with potassium-sparing diuretics and potassium preparations can lead to a significant increase in the concentration of potassium in the blood serum (especially against the background of renal failure) up to a fatal outcome.
    • ⓘ ACE inhibitors should not be prescribed in combination with potassium-sparing diuretics and potassium preparations; the exception is patients with hypokalemia (with constant monitoring of potassium concentration in blood plasma and ECG parameters).
    • ⓘ It should be taken into account that when using indapamide in combination with potassium-sparing diuretics or potassium preparations, the development of hypokalemia or hyperkalemia is not excluded (especially in patients with diabetes mellitus and renal insufficiency).
    • ⓘ When taken simultaneously with ACE inhibitors, the risk of hyperkalemia also increases, and with lithium preparations, the risk of hypothyroidism and goiter.
  • Negative interactions
    • ⓘ The combined use of ACE inhibitors and potassium-sparing diuretics (for example, spironolactone, triamterene, amiloride, eplerenone (a derivative of spironolactone)), potassium preparations and potassium-sparing products and dietary supplements can lead to a significant increase in serum potassium.
  • Unclear interactions
    • ⓘ Potassium-sparing diuretics, potassium preparations and potassium-containing products and dietary supplements.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,027,037 possible combinations of drugs and their components were found 412,563 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-01-01

Category - medicine