Compatibility «Etoricoxib» and «Amlodipine+Olmasartan medoxomil»

• Interactions Etoricoxib with Amlodipine+Olmasartan medoxomil

  • Dangerous interactions
    • ⓘ Concomitant use with potassium-sparing diuretics, potassium preparations, salt substitutes containing potassium, or other drugs that increase the potassium content in blood plasma (for example, NSAIDs, including selective COX-2 inhibitors, immunosuppressants (e.g. cyclosporine or tacrolimus), trimethoprim, ACE inhibitors, heparin) is not recommended.
    • ⓘ With the simultaneous use of NSAIDs, including non-selective NSAIDs, selective COX-2 inhibitors, acetylsalicylic acid (at a dose of more than 3 g / day), and ARA II, the risk of acute renal failure may increase, therefore, monitoring of renal function is recommended, especially at the beginning of use, as well as regular intake of sufficient fluid by the patient.
    • ⓘ In some patients with impaired renal function (for example, dehydration or elderly patients with impaired renal function), concomitant administration of an ACE inhibitor or ARA II and COX inhibitors may lead to further deterioration of renal function, including the development of acute renal failure, which is usually reversible.
    • ⓘ With the simultaneous use of NSAIDs and angiotensin II receptor antagonists, there may be a risk of acute renal failure, therefore, monitoring of renal function at the beginning of treatment, as well as regular intake of sufficient fluids, is recommended.
  • Negative interactions
    • ⓘ At the same time, the simultaneous use of NSAIDs and ARA II may lead to a weakening of the antihypertensive effect of ARA II and a partial loss of their therapeutic effectiveness.
    • ⓘ Diuretics, ACE inhibitors and ARA II.
    • ⓘ NSAIDs can reduce the effect of diuretics and other antihypertensive drugs.
    • ⓘ This interaction should be considered in patients taking etoricoxib concomitantly with ACE inhibitors or ARA II.
    • ⓘ NSAIDs, including acetylsalicylic acid in doses of more than 3 g / day, as well as COX-2 inhibitors and angiotensin II receptor antagonists can act synergistically, reducing glomerular filtration.
  • No interactions
    • ⓘ Unlike other BMCC, no clinically significant interaction of amlodipine was found when combined with nonsteroidal anti-inflammatory drugs (NSAIDs), including indomethacin.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,039,738 possible combinations of drugs and their components were found 412,575 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-05-28

Category - medicine