Compatibility «Gliclazide» and «Acetylsalicylic acid»
Between «Gliclazide» and «Acetylsalicylic acid» found 1 dangerous and 5 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Acetylsalicylic acid |
✘Gliclazide Analogs | |
✘Acetylsalicylic acid Analogs |
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Interactions Gliclazide with Acetylsalicylic acid
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Dangerous interactions
- NSAIDs increase the risk of hypoglycemia, enhancing the effect of lowering blood glucose levels.
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Negative interactions
- Hypoglycemia as a result of drug interaction may increase with the simultaneous use of sulfonylurea derivatives with drugs such as long-acting sulfonamides, tuberculostatics, NSAIDs, fibrates, MAO inhibitors, salicylates, probenecid, beta-blockers, azole antifungal drugs (for oral and parenteral use), antagonists of H2-antihistamines receptors, ACE inhibitors and clarithromycin.
- Antidiabetic drugs (Insulin preparations, sulfonylurea derivatives (bucarban, butamide, etc.), biguanides (glybutide, etc.)) + Butadione, clofibrate, salicylates => Increased hypoglycemia.
- Increases the toxicity of methotrexate, reducing its renal clearance, the effects of narcotic analgesics (codeine), oral antidiabetic drugs, heparin, indirect anticoagulants, thrombolytics and inhibitors of platelet aggregation, reduces the effect of uricosuric drugs (benzbromarone, sulfinpyrazone), hypotensive agents, diuretics (spironolactone, furosemide).
- Antidiabetic drugs, such as insulin, sulfonylurea derivatives.
- Increased hypoglycemic effect when using high doses of acetylsalicylic acid due to its hypoglycemic effect and displacement of sulfonylurea derivatives from the sites of binding to plasma proteins.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
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Additional information
- Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,994,378 possible combinations of drugs and their components were found 412,530 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-12-19
Category - medicine