Compatibility «Alfuzosin» and «Amlodipine+Perindopril»

• Interactions Alfuzosin with Amlodipine+Perindopril

  • Dangerous interactions
    • ⓘ Alfuzosin (G04CA01) + Calcium channel blockers (C02) => With the simultaneous use of alfuzosin with antihypertensive drugs (especially calcium channel blockers), a marked decrease in blood pressure is possible, up to the development of collapse (!).
  • Negative interactions
    • ⓘ If the patient needs extracorporeal therapy, the possibility of using another type of dialysis membrane or another class of antihypertensive drugs should be considered.
    • ⓘ Antihypertensive agents (e.g. beta-blockers) and vasodilators.
    • ⓘ Enhances the effects of antihypertensive drugs, in pm BCC, and general anesthetics (possible instability of blood pressure during anesthesia).
    • ⓘ It enhances the effect of antihypertensive drugs (increased antihypertensive effect and the risk of postural hypotension (additive effect)), including slow calcium channel blockers and general anesthetics (possible instability of blood pressure during anesthesia).
    • ⓘ Other antihypertensive and antianginal drugs.
    • ⓘ The possibility of hypotensive effects can be minimized by reducing the dose or canceling the diuretic, or increasing salt intake before starting treatment with perindopril.
    • ⓘ Antihypertensive and vasodilating agents.
    • ⓘ It enhances the antihypertensive effect of ACE inhibitors, blood pressure monitoring is required and, if necessary, dose adjustment of antihypertensive drugs.
  • Positive interactions
    • ⓘ The antihypertensive effect of perindopril may be enhanced when combined with other antihypertensive drugs, vasodilators, nitrates of short and prolonged action.
  • Unclear interactions
    • ⓘ Alpha-blockers (prazosin, alfuzosin, doxazosin, tamsulosin, terazosin).

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,037,924 possible combinations of drugs and their components were found 412,574 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-05-07

Category - medicine