Compatibility «Lindynette» and «Qlaira»

• Interactions Lindynette with Qlaira

  • Negative interactions
    • ⓘ The contraceptive effect of oral contraceptives decreases with the simultaneous use of rifampicin, breakthrough bleeding and menstrual disorders become more frequent.
    • ⓘ It may be necessary to adjust the dosage regimen when using hypoglycemic agents, etc.; oral contraceptives may reduce carbohydrate tolerance, increase the need for insulin or oral antidiabetic agents.
    • ⓘ Ethinylestradiol and Dienogest belong to the same pharmaceutical group: Estrogens, progestogens; their homologues and antagonists.
    • ⓘ Ethinylestradiol and Estradiol valerate belong to the same pharmaceutical group: Estrogens, progestogens; their homologues and antagonists.
    • ⓘ Strong and medium-strength CYP3A4 inhibitors such as azole antimycotics (e.g., itraconazole, voriconazole, fluconazole), verapamil, macrolides (e.g., clarithromycin, erythromycin), diltiazem and grapefruit juice may increase plasma concentrations of estrogen or progestin, or both.
    • ⓘ Dienogest and Gestodene belong to the same pharmaceutical group: Estrogens, progestogens; their homologues and antagonists.
    • ⓘ Estradiol valerate and Gestodene belong to the same pharmaceutical group: Estrogens, progestogens; their homologues and antagonists.
  • Positive interactions
    • ⓘ During treatment with the above drugs, it is recommended to use an additional method of contraception (condom, spermicidal gel) simultaneously with oral contraception.
  • Unclear interactions
    • ⓘ Ethinylestradiol + Dienogest analgin and citramon are used together in 7 preparations.
    • ⓘ Dienogest is a CYP3A4 substrate.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,027,037 possible combinations of drugs and their components were found 412,563 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-01-01

Category - medicine