Compatibility «Maltofer» and «L-Thyroxin»

• Interactions Maltofer with L-Thyroxin

  • Negative interactions
    • ⓘ Drugs that alter the secretion of thyroid hormones and/or reduce the activity of T₄-5'-deiodinase (conversion of T₄ into T₃) can lead to the development of hypothyroidism.
    • ⓘ Drugs that can increase the secretion of thyroid hormones, which can lead to the development of hyperthyroidism in euthyroid patients with Graves' disease who previously received antithyroid drugs, or in patients with euthyroidism with thyroid autonomy.
    • ⓘ Iodides and drugs containing therapeutic amounts of iodide can cause hyperthyroidism in euthyroid patients with Graves' disease who have previously received antithyroid drugs, or in patients with euthyroidism with thyroid autonomy (for example, a multi-nodular goiter or hyperfunctional thyroid adenoma).
    • ⓘ Drugs that can reduce the absorption of T₄, which can lead to the development of hypothyroidism.
    • ⓘ Drugs that can increase the metabolism of T₄ and T₃ in the liver, which can lead to the development of hypothyroidism.
    • ⓘ The level of digitalis glycosides in the blood serum may be reduced with hyperthyroidism or with the transition of a patient with hypothyroidism to an euthyroid state.
    • ⓘ Excessive doses of thyroid hormones when used with growth hormones can accelerate the closure of epiphyseal growth zones.
  • Unclear interactions
    • ⓘ Drugs that reduce the secretion of TSH (the decrease is insignificant, therefore hypothyroidism does not occur).
    • ⓘ The effect of some beta-blockers can be disrupted when a patient with hypothyroidism goes into an euthyroid state.
    • ⓘ The effects of amiodarone and iodine are also lower in euthyroid patients with Graves' disease who previously received antithyroid drugs, or in euthyroid patients with thyroid autonomy.
    • ⓘ Thyroid hormones increase the anticoagulant activity of oral anticoagulants.
    • ⓘ Some statins may increase the need for thyroid hormones.
    • ⓘ Concomitant use was associated with the need to increase the dose of levothyroxine sodium in patients with hypothyroidism.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,027,037 possible combinations of drugs and their components were found 412,563 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-01-01

Category - medicine