Compatibility «Piribedil» and «Levodopa+Benserazide»
Between «Piribedil» and «Levodopa+Benserazide» found 4 dangerous and 4 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Levodopa+Benserazide |
✘Piribedil Analogs | |
✘Levodopa+Benserazide [Levodopa and more 1Benserazide] Analogs |
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Interactions Piribedil with Levodopa+Benserazide
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Dangerous interactions
Due to the mutual antagonism between dopaminergic antiparkinsonian drugs and neuroleptics, concomitant administration with neuroleptics (. Patients with extrapyramidal syndrome caused by taking neuroleptics should be prescribed therapy with anticholinergic drugs and should not be prescribed dopaminergic antiparkinsonian drugs (due to blocking of dopaminergic receptors by neuroleptics). If it is necessary to prescribe neuroleptics to patients with Parkinson's disease treated with dopaminergic antiparkinsonian drugs, the dose of the latter should be gradually reduced until final withdrawal (sudden withdrawal of dopaminergic drugs is associated with the risk of developing malignant neuroleptic syndrome) (see 'Special instructions'). Due to the mutual antagonism between dopaminergic antiparkinsonian drugs and tetrabenazine, simultaneous administration of these drugs is not recommended. -
Negative interactions
Other antiparkinsonian drugs (anticholinergic drugs, amantadine, dopamine agonists) - increased side effects. Levodopa/ benserazide may be used with other antiparkinsonian drugs (anticholinergic drugs, amantadine, dopamine receptor agonists), while not only desirable but also undesirable effects may be enhanced. Levodopa and Piribedil belong to the same pharmaceutical group: Antiparkinsonian drugs. Levodopa and Piribedil belong to the same pharmaceutical group: Dopaminomimetics.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,974,420 possible combinations of drugs and their components were found 412,510 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-05-02
Category - medicine