Compatibility «Hyperici perforati herbae extract» and «Escitalopram»
Between «Hyperici perforati herbae extract» and «Escitalopram» found 3 dangerous and 1 negative interaction, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Escitalopram |
✘Hyperici perforati herbae extract Analogs | |
✘Escitalopram Analogs |
-
Interactions Hyperici perforati herbae extract with Escitalopram
-
Dangerous interactions
The simultaneous use of St. John's wort with cyclosporine, sirolimus, tacrolimus or indinavir and other protease inhibitors used to treat HIV, irinotecan and other cytostatics, as well as antidepressants is not recommended (see the section Contraindications). Simultaneous use with drugs whose metabolism involves cytochrome P450 isoenzymes SUR3A4, SUR2C9, SUR2C19 or drugs transported by P-gp may cause a decrease in their effectiveness: oral coumarin-type anticoagulants (in pm warfarin); drugs used in the treatment of HIV infection; protease inhibitors used in the treatment of viral hepatitis C; immunosuppressants; cytostatic agents (irinotecan, protein kinase inhibitors such as imatinib, periwinkle alkaloids, taxanes, etoposide, cyclophosphamide); other antidepressants. Increases the antidepressant effect of MAO inhibitors, while increasing the risk of hypertensive crises (do not take simultaneously with antidepressant MAO inhibitors, the interval between administration should be at least 14 days). -
Negative interactions
Hyperici perforati herbae extract and Escitalopram belong to the same pharmaceutical group: Antidepressants. -
No interactions
St. John's wort dry extract may promote serotonergic effects in combination with antidepressants such as serotonin reuptake inhibitors (e.g. sertraline, paroxetine, nefazodone), buspirone or triptans. -
Positive interactions
With the simultaneous use of St. John's wort with a number of antidepressants (nefazodone, paroxetine, sertraline), the pharmacological effect of the latter may increase.
-
Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,974,420 possible combinations of drugs and their components were found 412,510 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-05-02
Category - medicine