Compatibility «Atenolol» and «Timolol bufus»
Between «Atenolol» and «Timolol bufus» found 2 dangerous and 9 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Timolol bufus |
✘Atenolol Analogs | |
✘Timolol bufus [Timolol maleate and more 1Timolol] Analogs |
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Interactions Atenolol with Timolol bufus
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Dangerous interactions
CYPIID 6 inhibitors (in pm quinidine, cimetidine) can increase the concentration of timolol in plasma, increasing the risk of systemic side effects of beta-blockers; (in pm, decreased heart rate, depression). With the simultaneous use of beta‑blockers with nonhydropyridine BMCC, such as verapamil and diltiazem, the negative effect on myocardial contractility and atrioventricular conduction increases, which can lead to severe arterial hypotension, atrioventricular blockade and cardiac arrest. -
Negative interactions
Use with caution with antihypertensive drugs, other beta-blockers, insulin or oral hypoglycemic drugs, glucocorticosteroids, psychoactive drugs, as well as drugs whose effect is associated with increased release of epinephrine. Atenolol and Timolol maleate belong to the same pharmaceutical group: Beta blockers. Beta‑blockers may increase the risk and severity of 'ricochet' hypertension (withdrawal syndrome) upon discontinuation of clonidine. With simultaneous use of atenolol and clonidine, the beta‑blocker should be discontinued a few days before discontinuation of clonidine. If clonidine is supposed to be replaced with atenolol, then a beta‑blocker should be prescribed a few days after clonidine withdrawal. Fingolimod can enhance the negative chronotropic effect of beta‑blockers and lead to severe bradycardia. It is recommended to start combination therapy in a hospital setting and carry out appropriate monitoring (long‑term heart rate monitoring is indicated, at least until the morning of the next day after the first simultaneous intake of fingolimod and beta-blockers). Drugs that deplete the catecholamine depot (such as reserpine or guanethidine) can enhance the effect of beta‑blockers and lead to severe bradycardia or arterial hypotension. Timolol and Atenolol belong to the same pharmaceutical group: Beta blockers. -
Positive interactions
Epinephrine, pilocarpine, systemic beta-blockers enhance the effect. In addition to the MAO inhibitor B), they can enhance the antihypertensive effect of beta‑blockers. With simultaneous systemic and topical use of beta-blockers, mutual enhancement of effects is possible.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,972,605 possible combinations of drugs and their components were found 412,508 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-04-11
Category - medicine