Compatibility «Berlipril» and «Fokusin Combi»
Between «Berlipril» and «Fokusin Combi» found 1 dangerous and 7 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Fokusin Combi |
✘Berlipril [Enalapril] Analogs | |
✘Fokusin Combi [Tamsulosin+Finasteride [set] and more 2Tamsulosin, Finasteride] Analogs |
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Interactions Berlipril with Fokusin Combi
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Dangerous interactions
In three studies in patients with hypertension (47-79 years old), whose blood pressure was controlled by stable doses of nifedipine, atenolol or enalapril for at least 3 months, tamsulosin intake at a dose of 0.4 mg for 7 days, and then at a dose of 0.8 mg for another 7 days (n=8 in each study) was not It had a clinically significant effect on blood pressure and heart rate compared with placebo (n=4 in each study). -
Negative interactions
The possibility of hypotensive effects when using enalapril can be minimized by stopping the diuretic or increasing salt intake before starting treatment with enalapril. Other antihypertensive drugs. The simultaneous use of enalapril with alpha‑blockers, beta‑blockers and ganglioblockers should be carried out under careful medical supervision. NSAIDs, including selective COX‑2 inhibitors and acetylsalicylic acid in doses of 3 g/day and above, can reduce the antihypertensive effect of diuretics and other antihypertensive agents. Blood pressure should be carefully monitored and, if necessary, the dose of antihypertensive drugs should be adjusted. There was no clinically significant drug interaction with the combined use of tamsulosin at a dose of 0.4 or 0.8 mg and nifedipine, atenolol, enalapril, digoxin, furosemide or theophylline. Alpha-blockers and PDE-5 inhibitors are vasodilators that reduce blood pressure. -
No interactions
No interaction was found with the simultaneous use of tamsulosin and atenolol, enalapril, nifedipine or theophylline. There was no clinically significant interaction with the combined use of finasteride with the following drugs: warfarin, ACE inhibitors, α1-blockers, theophylline, acetylsalicylic acid, paracetamol, beta-blockers, diuretics, nitrates, BCC, anticonvulsants, NSAIDs, benzodiazepines, quinolones, blockers H2-histamine receptors, HMG-CoA reductase inhibitors. When tamsulosin is co-administered with nifedipine, atenolol or enalapril, dose adjustment is not required. -
Positive interactions
When using enalapril simultaneously with other antihypertensive agents, especially with diuretics, an increased antihypertensive effect may be observed. -
Unclear interactions
Nifedipine, atenolol, enalapril.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,972,605 possible combinations of drugs and their components were found 412,508 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-04-11
Category - medicine