Meconinum

 Meconine (Opianyl), с10H10O4. A glucoside obtained from Opium. Preparation for use, Triturations of the crystals.

 Respiration 20 (before the injection); 16 (after one hour); 16 to 17, regular (after two hours and a quarter). Respiration 20 (before first proving); 17 (two hours after second proving).

 Pulse 75 (before the injection); 66 (after one and two and a quarter hours). Pulse 75 (before first proving); 65, regular, not quite so full as before the injection (two hours after second proving). Pulse 75 (before first proving); 66 (one hour after third proving).

 Secretions free. Secretions quite free. Felt very comfortable (after one hour).

 Somnolency (after twenty minutes); had had a few light dozes (after two hours); somnolency continued; went home and slept well all night and was sleepy, as usual after his opiate injections, all the next day. Felt very comfortable and sleepy, but not more so than on last occasion (after one hour); somnolency increased during last hour, but he had not actually slept since the injection (after two hours and a quarter); went home and slept well, and felt sleepy throughout the next day. Slight somnolency (after about half an hour); had continued decidedly sleepy, but effect was passing off (after two hours and a quarter); did not sleep well during the night; slept most of the next day.