Colocynthinum

 An active principle (glucoside) of сitrullus сolocynthis.
 Formula: с H O Preparation: Dilutions in alcohol.

 Mind.
 Depression, towards evening. Great depression, all day.
 Great depression, in the morning. Remarkably depressed, in the evening.
 Unusually out of humor.

 Head.
 General Head.
 Affection of the whole head. Painfulness of the whole head, especially of the temporal and frontal regions, scalp and eyeballs, aggravated by moving the eyes, straining the sight or bending forwards. Headache aggravated by riding in the rail cars, obliging me to move slowly and to tread softly, otherwise the brain seemed to shake about, as if loose, against the skull (in the median vertical region); this was accompanied by very severe sore pain, and as it lasted during a quarter of an hour’s walk, it put me in a very bad humor. Stitches in the brain.
 Forehead.
 Dull headache in the frontal region.
 Temples.
 Pressure in the temple. Sensitiveness of the temples and forehead.
 Vertex.
 Occasional pressure on the vertex, in the evening.
 Sides.
 Painfulness of the whole left side of the head.
 Occiput.
 Heaviness and pain in the occiput. Sensitiveness of the cerebellum, on turning the head. Heavy tread caused stitches to traverse the occiput. On coughing, exceedingly painful stitches darting through the cerebellum like lightning.
 Eye.
 Lids.
 Feeling of pressure and swelling in the lower eyelids.
 Formication of the eyelids.
 Ball.
 Painfulness of the eyeballs. Aching in the eyeballs, aggravated by straining the sight, moving the eyes rapidly and bowing the head, lasting all day.
 Vision.
 It seemed as though vision were sharper than usual, on going out; looking through the ordinary spectacles was rather straining.
 Ear.
 Tickling in the left external ear, with burning of the tip.
 Face.
 Pressure in the left cheek bone.

 Confusion and Vertigo.
 Slight intimation of confusion of the head. Slight confusion of the head. Slight confusion in the forehead.
 Confusion in the left side of the head, especially in the temporal region. Transient attack of vertigo.

 Teeth.
 Pain in a hollow molar, and drawing in the incisors, with sensation of swelling of the left cheek. сrawling in the lower incisors on the left side.
 Tongue.
 Tongue moist, slightly coated.
 Throat.
 Feeling of roughness in the throat. вurning in the posterior wall of the pharynx.

 Taste.
 Persistent, disgusting, bitter taste in the mouth.
 Persistent, earthy, bitter taste upon the tongue.
 Prickling and metallic taste on the tip of the tongue.
 Appetite.
 Appetite began to increase a little. Appetite somewhat diminished.
 Thirst.
 Thirst. Much thirst.
 Heartburn.
 Transient heartburn, in the forenoon.

 Stomach.
 Continual burning pressure in the stomach, up into the oesophagus, during the following forenoon. Sticking in the epigastrium. Sticking, continuing several minutes, in the epigastrium, which was tense and inflated. Fine stitches in the pit of the stomach. Pulsation in the pit of the stomach, accompanied by prickling stitches on the back, in the neighborhood of the middle thoracic vertebrae.
 Abdomen.
 Umbilical.
 Pinching and movements in the umbilical region.
 Violent pinching in the umbilical region.
 General Abdomen.
 A gentle feeling of warmth in the abdomen, as if from a congestion of the bowels, followed by a copious discharge of flatus, in the afternoon. Pinching in the bowels. Awoke with griping and movements in the abdomen. Intimations of colic, with inflation in the umbilical region, in the morning; slight colic some fingers’ breadth below the navel (after six hours). Slight intimations of colic, drawing from the hypogastrium erections, and pain in the buttock. сolic pains with inflation of the abdomen.
 Hypogastrium and Iliac Region.
 Tension in the right inguinal region, and drawing along the spermatic cord into the right testicle, which was somewhat sensitive towards evening;worse the next morning and aggravated by walking, bending over, and going upstairs.
 When walking, stitches from the small of the back to the groin, and a hard tread caused pain in the right testicle, so that at last I feared to move about; at the same time the left testicle became sensitive also. The pain was much ameliorated by rest, and especially by bending over.
 Rectum and Anus.
 Tickling in the rectum. Feeling of moisture at the anus.
 Inclination to stool, several times in the afternoon.
 Strong, irresistible inclination to stool;a scanty brownish red evacuation, with painful tenesmus, lasting some ten minutes.
 Stool.
 Some slight, rapid, brown, soft stools, in the afternoon. Two soft brown stools every day. Four painless, pappy stools during the day.
 Two scanty, fluid stools, with no tenesmus, and scarcely perceptible colic, one at midday, and the other in the evening.
 The next day, two soft, rapidly and easily discharged stools in quick succession. Towards 11 p. m. a copious, thin, pappy evacuation, easily and rapidly discharged, without tenesmus.

 Urethra.
 Sensations of tenesmus in the urethra and rectum, after urinating. Frequent urging to urinate, in the evening.
 Micturition.
 Frequent urination. Urine fiery; becomes cloudy on standing but deposits no sediment.
 Sexual Organs.
 Congestion towards the genital organs, especially the scrotum, with feeling of heat and persistent burning in a small spot upon the same, without erections. сramp like pain in the penis, which lasted several minutes, during which it seemed as if it were bent double.
 Crawling in the penis, with sexual desire. The right testicle and particularly the epididymis, was considerably swollen and painful to external touch. A pollution at night, a very unusual occurrence with him.

 Short hacking cough, excited by a tickling in the throat. Dry cough at times. Loose cough. сough excited by the roughness in the throat, caused no pain in either the chest or abdomen, and was accompanied by a whitish yellow mucus, expectorated without difficulty.
 Frequent cough in the early morning, and easy expectoration of a thick, yellow mucus.
 Chest.
 Chest somewhat painful and oppressed.

 Heart’s action. Palpitation.
 Pulse.
 Somewhat accelerated pulse. Pulse over 90. Pulse 92.
 Pulse 100.

 Sharp in pressing pain in some spots on the nape of the neck, as if from a sprain, aggravated by movement, the spot itself being sensitive to pressure from without. Painfulness and feeling of heat along the whole spine. Stitches in the region oft he lowest dorsal vertebrae.
 Extremities in General.
 Slight pains here and there in the left leg and arm.
 Superior Extremities.
 Tearing in the left shoulder. Frequently repeated stitches from the left axilla down to the left elbow. Paralytic weakness of the right forearm, while writing. сramp like pain in the muscles of the left wrist.
 Inferior Extremities.
 Weakness of the legs, in the forenoon. Great stiffness and heaviness in the tibiae. Prickling in the left calf and sole.
 Painfulness of the malleoli. вurning sticking and sensation of warmth on the dorsum of the right foot; pressing digging pain in the external side of second toe of left foot. вurning pain in both soles, with feeling as if they were swollen. Pain in the right great toe, accompanied by a dull, not easily described feeling, as of heat, on various parts of the right thigh, especially on the posterior side in the course of the sciatic nerve; at the same time, a similar sensation in the external ball of the little toe of the same side; after some hours, pressure in the left great toe.

 Great desire to lie down, requiring great exertion to get off the bed. Great debility. Unusual debility, towards evening. All the symptoms were developed when seated, lasted almost two hours, and disappeared entirely on walking. A cup of black coffee relieved the symptoms, but they did not entirely disappear until I went to bed, which I was glad to do at 7 a. m.
 Sweat.
 Sweat, in the morning. Profuse sweat, towards morning.

 Restless sleep, with many vivid dreams. Very restless sleep, at night.
 Tossing about at night. Vivid dreams, at night.
 Uninterrupted, confused dreams.

 Chilliness.
 Disagreeable feeling of chilliness.
 Heat.
 Heat in the whole body. Dry heat, at night. Hotter than usual all over, in the evening. Decided feeling of heat in the stomach as if from hot water.

 Conditions. Aggravation.
 (Morning), Depression; early, cough.
 (Forenoon), Heartburn; weakness of legs.
 (Afternoon), All symptoms; towards evening, depression; towards evening, tension in inguinal region; towards evening, debility.
 (Evening), All symptoms; depression; pressure on vertex; urging to urinate; heat.
 (Night), Dry heat; towards morning, sweat.
 (Ascending stairs), Tension in inguinal region, etc.
 (Bending forwards), Painfulness of head; tension in inguinal region, etc.
 (Bowing head), Aching in eyeballs.
 (On coughing), Stitches through cerebellum.
 (Movement), Pain in nape of neck.
 (Moving eyes), Painfulness of head; aching in eyeballs.
 (Riding in rail car), Headache.
 (When seated), All symptoms developed.
 (Straining the sight), Painfulness of head; aching in eyeballs.
 (Heavy head), Stitches through occiput; pain in testicle.
 (Walking), Tension in inguinal region, etc.; stitches in groin.
 (While writing), Weakness of forearm.
 Amelioration.
 (Bending over), Pain in testicle.
 (Black coffee), The symptoms.
 (Rest), All symptoms.; pain in testicle.
 (On walking), all symptoms disappeared.

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