Compatibility «Ascalcin» and «Holms»

• Interactions Ascalcin with Holms

  • Negative interactions
    • ⓘ Salicylates (N02BA) + Ammonium chloride, calcium chloride and other drugs that increase urine acidity => Increased action of salicylates up to the development of salicylism phenomena (the appearance of tinnitus, hearing loss).
    • ⓘ Increases the concentration of salicylates in the blood (increases the risk of crystalluria), ethinyl estradiol, benzylpenicillin and tetracyclines, reduces oral contraceptives.
    • ⓘ Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline drinks reduce absorption and assimilation.
    • ⓘ Quinoline preparations, calcium chloride, salicylates, corticosteroids deplete vitamin C reserves with prolonged use.
    • ⓘ Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline drinks reduce the absorption and assimilation of ascorbic acid.
    • ⓘ Ascorbic acid increases the risk of crystalluria in the treatment of short-acting salicylates and sulfonamides, slows down the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood.
    • ⓘ Quinoline preparations, calcium chloride, salicylates, glucocorticosteroids deplete ascorbic acid reserves with prolonged use.
    • ⓘ Enhances the effect of steroid and NSAIDs, cardiac glycosides, reduces the toxicity of the latter, as well as vitamins A and D.
  • Positive interactions
    • ⓘ Vitamin E enhances the effect of glucocorticosteroid drugs, nonsteroidal anti-inflammatory drugs, and cardiac glycosides.
  • Unclear interactions
    • ⓘ Acetylsalicylic acid + Ascorbic acid analgin and citramon are used together in 12 preparations.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 169,990,749 possible combinations of drugs and their components were found 412,526 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2024-11-07

Category - medicine