Compatibility «Algeldrate» and «Domperidone+Omepazole»

• Interactions Algeldrate with Domperidone+Omepazole

  • Negative interactions
    • ⓘ Drugs that lengthen the QT interval, - class IA antiarrhythmic drugs (e.g. disopyramide, hydroquinidine, quinidine), Class III antiarrhythmic drugs (e.g. amiodarone, dofetilide, dronedarone, ibutilide, sotalol), antipsychotics (e.g. haloperidol, pimozide, sertindol), antidepressants (e.g. citalopram, escitalopram), antibiotics (erythromycin, levofloxacin, moxifloxacin, spiramycin), antifungal drugs (e.g. pentamidine), antimalarial drugs (in particular halofantrin, lumefantrin), gastrointestinal drugs (e.g. cisapride, dolacetron, prucalopride), antihistamines (e.g. mechitazine, misolastine), antitumor drugs (e.g. toremifene, vandetanib), other drugs (e.g. vincamine, bepridil, difemanyl methylsulfate, methadone), strong inhibitors of the CYP3A4 isoenzyme (protease inhibitors, antifungal agents of the azole series, some antibiotics from the macrolide group - erythromycin, clarithromycin, telithromycin).
    • ⓘ Cimetidine, sodium bicarbonate, and other antacid and antisecretory drugs reduce the bioavailability of domperidone.
    • ⓘ Since domperidone enhances peristalsis of the stomach and small intestine, it can accelerate the absorption of drugs from the small intestine, while simultaneously slowing the absorption of drugs absorbed from the stomach, especially with delayed release or with an intestinal coating.
  • No interactions
    • ⓘ The effect of omeprazole on antacids, theophylline, caffeine, quinidine, lidocaine, propranolol, ethanol has not been revealed.
  • Unclear interactions
    • ⓘ - some gastrointestinal agents (for example, cisapride, dolazetron, prucalopride);.
    • ⓘ Simultaneous use of domperidone with antacids or blockers of H₂receptors does not reduce the absorption of domperidone.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 169,994,378 possible combinations of drugs and their components were found 412,530 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2024-12-19

Category - medicine