Compatibility «Fluoxetine» and «Diazepam»
Between «Fluoxetine» and «Diazepam» found 1 dangerous and 3 negative interactions, joint admission is not recommended without consulting a doctor.
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Interactions Fluoxetine with Diazepam
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Dangerous interactions
- with hypnotics, sedatives, narcotic analgesics, other tranquilizers, benzodiazepine derivatives, muscle relaxants, general anesthesia, antidepressants, neuroleptics, alcohol - a sharp increase in the depressive effect on the central nervous system;.
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Negative interactions
- In patients receiving stable doses of phenytoin and carbamazepine, plasma concentrations of anticonvulsants and clinical anticonvulsant toxicity increased after the start of concomitant treatment with fluoxetine.
- Microsomal oxidation inhibitors (in pm cimetidine, ketoconazole, fluvoxamine, fluoxetine, omeprazole) alter the pharmacokinetics and increase the duration of the effect of diazepam.
- with cimetidine, disulfiram, erythromycin, fluoxetine, as well as with oral contraceptives and estrogen-containing drugs that competitively inhibit liver metabolism (oxidation processes) - it is possible to slow down the metabolism of diazepam and increase its plasma concentration;.
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Unclear interactions
- Benzodiazepines.
- Anticonvulsants.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- Do you need an API for interactions/drug analogues for your project? Write to us.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,994,378 possible combinations of drugs and their components were found 412,530 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-12-19
Category - medicine