Compatibility «Theophylline» and «Ciprofloxacin»

• Interactions Theophylline with Ciprofloxacin

  • Dangerous interactions
    • ⓘ Simultaneous use of ciprofloxacin and theophylline may lead to an increased risk of adverse reactions in the patient, in pm from the central nervous system.
    • ⓘ If simultaneous use cannot be avoided, it is recommended to constantly monitor the concentration of theophylline in the blood serum and, if necessary, reduce the dose of theophylline (see 'Precautions').
    • ⓘ Quinolones (J01M)/ Fluoroquinolones (J01MA) + Xanthines (theophylline, aminophylline, caffeine) => Increased risk of xanthine toxicity (especially with ciprofloxacin).
  • Negative interactions
    • ⓘ When used concomitantly with enoxacin or other fluoroquinolones, a significant increase in the concentration of theophylline in blood plasma is possible.
    • ⓘ Reduces clearance and increases plasma levels of caffeine, aminophylline and theophylline (increases the likelihood of side effects).
    • ⓘ Simultaneous use of ciprofloxacin and caffeine or pentoxifylline may lead to a decrease in clearance, an increase in the concentration of xanthine derivatives in serum and prolongation of T_1/2 from serum.
    • ⓘ Caution should be exercised, the toxicity of xanthine should be monitored and the dose adjusted if necessary.
  • Unclear interactions
    • ⓘ Theophylline.
    • ⓘ Other xanthine derivatives.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 169,994,378 possible combinations of drugs and their components were found 412,530 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2024-12-19

Category - medicine