Compatibility «Periciazine» and «Clomipramine»

• Interactions Periciazine with Clomipramine

  • Dangerous interactions
    • ⓘ With drugs capable of prolonging the QT interval (in pm, class IA and III antiarrhythmic agents, moxifloxacin, erythromycin, methadone, mefloquine, sertindole, tricyclic antidepressants, lithium salts, cisapride) - increased risk of arrhythmias (see With caution).
    • ⓘ With other drugs that have a depressing effect on the central nervous system: morphine derivatives (analgesics, antitussives), barbiturates, benzodiazepines, non-benzodiazepine anxiolytics, hypnotics, other neuroleptics, antidepressants with sedative effect (amitriptyline, doxepin, mianserin, mirtazapine, trimipramine), histamine H blockers₁ -receptors with sedative effect, antihypertensive agents of central action, baclofen, thalidomide, pisotifen - the risk of additional depressive effects on the central nervous system, respiratory depression (which can be dangerous for people driving vehicles and mechanisms).
    • ⓘ With tricyclic antidepressants, MAO inhibitors, maprotilin - an increase in the risk of developing a malignant neuroleptic syndrome, possibly an increase and an increase in the duration of sedative and anticholinergic effects.
    • ⓘ With atropine and other cholinolytics, as well as drugs with cholinolytic action (imipramine antidepressants, histamine H₁ receptor blockers with sedative effect, anticholinergic antiparkinsonian drugs, atropine-like antispasmodics, disopyramide) - the possibility of accumulation of undesirable effects associated with cholinolytic action, such as urinary retention, constipation, dry mouth, heat stroke, as well as reducing the antipsychotic effect of antipsychotics.
    • ⓘ With hepatotoxic drugs - an increase in the risk of hepatotoxic action.
    • ⓘ M-holinoblockers and antipsychotic medications increase the risk of hyperpyrexia (especially in hot weather).
    • ⓘ Clomipramine (N06AA04) + neuroleptics (N05) => Dangerous inhibition.
  • Negative interactions
    • ⓘ Drugs that depress the central nervous system:.
  • Unclear interactions
    • ⓘ Neuroleptics:.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 169,994,378 possible combinations of drugs and their components were found 412,530 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2024-12-19

Category - medicine