Compatibility «Adriblastina NovaMedica rapid dissolution» and «Life»

• Interactions Adriblastina NovaMedica rapid dissolution with Life

  • Dangerous interactions
    • ⓘ The simultaneous use of St. John's wort with cyclosporine, sirolimus, tacrolimus or indinavir and other protease inhibitors used to treat HIV, irinotecan and other cytostatics, as well as antidepressants is not recommended (see the section Contraindications).
    • ⓘ Simultaneous use with drugs whose metabolism involves cytochrome P450 isoenzymes SUR3A4, SUR2C9, SUR2C19 or drugs transported by P-gp may cause a decrease in their effectiveness: oral coumarin-type anticoagulants (in pm warfarin); drugs used in the treatment of HIV infection; protease inhibitors used in the treatment of viral hepatitis C; immunosuppressants; cytostatic agents (irinotecan, protein kinase inhibitors such as imatinib, periwinkle alkaloids, taxanes, etoposide, cyclophosphamide); other antidepressants.
  • Negative interactions
    • ⓘ Inducers of the CYP3A4 isoenzyme (for example, phenobarbital, phenytoin, St. John's wort preparations) and P‑gp inducers can reduce the concentration of doxorubicin.
    • ⓘ This may lead to a weakening and/or shortening of the duration of the clinical effect of coumarin anticoagulants (for example, phenprocumone, warfarin), immunosuppressants (for example, cyclosporine, sirolimus, tacrolimus), digoxin, indinavir and other protease inhibitors used to treat HIV, irinotecan and other cytostatics, amitriptyline, midazolam, theophylline.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
• Why do I need to
  • Avoid dangerous prescriptions for your patients.
  • Check the contraindications.
  • Evaluate the safety of therapy in the treatment of children.
  • See the compatibility of drugs with alcohol (enter it as a drug).
  • Point the doctor to the found interaction - you may need to adjust the therapy.
  • Do you need an API for interactions/drug analogues for your project? Write to us.
• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,036,109 possible combinations of drugs and their components were found 412,572 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-04-16

Category - medicine