Compatibility «Тенлиза» and «Humulin NPH»

• Interactions Тенлиза with Humulin NPH

  • Negative interactions
    • ⓘ With simultaneous administration of ACE inhibitors and hypoglycemic drugs (insulin and hypoglycemic agents for oral administration), the likelihood of a decrease in serum glucose concentration and the risk of hypoglycemia may increase.
    • ⓘ The hypoglycemic effect of insulin is weakened by: oral contraceptives, glucocorticoids, thyroid hormones, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, danazol, clonidine, BCC, diazoxide, morphine, phenytoin, nicotine.
    • ⓘ Antidiabetic drugs.
    • ⓘ The combined use of lisinopril and antidiabetic drugs (insulins, oral hypoglycemic agents) may cause an increased glucose-lowering effect with the risk of hypoglycemia.
    • ⓘ The Veterans Affairs Nephropathy in Diabetes (VA NEPHRON-D) trial included 1,448 patients with type 2 diabetes, an increased urinary albumin/creatinine ratio and a reduced calculated GFR (GFR from 30 to 89.9 ml/min) who were randomized to receive lisinopril or placebo during losartan therapy, median follow-up time it was 2.2 years old.
    • ⓘ Simultaneous administration of lisinopril and insulin, as well as oral hypoglycemic agents, can lead to the development of hypoglycemia.
    • ⓘ The hypoglycemic effect of insulin is enhanced by: oral hypoglycemic drugs, MAO inhibitors, ACE inhibitors, carbonic anhydrase inhibitors, non-selective beta-blockers, bromocriptine, octreotide, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine , lithium preparations, preparations containing ethanol.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
• Why do I need to
  • Avoid dangerous prescriptions for your patients.
  • Check the contraindications.
  • Evaluate the safety of therapy in the treatment of children.
  • See the compatibility of drugs with alcohol (enter it as a drug).
  • Point the doctor to the found interaction - you may need to adjust the therapy.
  • Do you need an API for interactions/drug analogues for your project? Write to us.
• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,032,480 possible combinations of drugs and their components were found 412,568 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-03-05

Category - medicine