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Tiludronic acid

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Found partially in the 16 (16) ⓘFound partially in the 16 treatment (16 of these, according to Kiberis statistics) in 0 selected books (authors) More... hide
  Effect Influence Cases ⓘ  Effect - how much the symptom improves in one treatment cycle on average. Example: drug Pain relief for cancer pain-Effectiveness (E) is high, but the effect (I) is negative, because the patient will get worse over time.
Influence of the symptom on the outcome of the patient's treatment as a whole (i.e., the importance of the symptom). Example: menopause can not be cured (E low). But some means during menopause will be better than others (I high).
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  1. Pharmacological Group
  2. Latin name
  3. Chemical name
  4. Used in the treatment of
  5. CAS Code
  6. Pharmacological action
  7. Indications for use
  8. Contraindications
  9. Use during pregnancy and lactation
  10. Side effects
  11. Interaction
  12. Application precautions
  13. Additional facts
  14. Analogs by action
  15. Included in the composition
Tiludronic acid

Pharmacological Group

Correctors of bone and cartilage metabolism

Latin name

 Acidum tiludronicum ( Acidi tiludronici).

Chemical name

 [[(п-Хлорфенил)тио]метилен]дифосфоновая кислота (и в виде динатриевой соли).

Used in the treatment of

CAS Code

 89987-06-4.

Pharmacological action

 Ингибирующее костную резорбцию, регулирующее кальций-фосфорный обмен.
 Подавляет активность остеокластов и стимулирует образование и активность остеобластов. Препятствует резорбции костной ткани и стимулирует процессы фиксации в ней кальция и фосфатов, угнетает остеолиз.

Indications for use

 Болезнь Педжета (у взрослых).

Contraindications

 Гиперчувствительность, тяжелая почечная недостаточность, юношеская болезнь Педжета.

Use during pregnancy and lactation

 Противопоказано.

Side effects

 Боли в области живота, тошнота, понос.

Interaction

 Несовместим с солями кальция (разрыв между приемом должен быть не менее 2 ч). Не следует сочетать с препаратами, действующими локально в ЖКТ, антацидами и индометацином.

Application precautions

 С осторожностью назначают пациентам с нарушением функции почек. Во время лечения необходим прием кальция (через 2 и более часов после Скелида) и витамина D. Нельзя применять в течение 2 ч до или после приема любой пищи или напитков.

Additional facts

 Описание было автоматически дополнено из инструкции препарата «Скелид», поскольку у самого действующего вещества нет подробного описания.

Analogs by action

Included in the composition

42a96bb5c8a2acfb07fc866444b97bf1
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