Другие названия и синонимы
nat-ar, Natrum arsenicosum, натриум арсеникозум.Источник описания
Encyclopedia of Pure Materia Medica - TF AllenФармакологическая группа
Дополнительные факты
Sodium arseniate, Na3AsO412H2O, a compound of Arsenic acid and Sodium. The Arsenious acid becomes, during the process of preparation, converted into Arsenic acid. Preparation: Solution in distilled water in the proportion of 10 grains to 1 ounce (tincture), (Allegheny provings); Triturations (Gourbeyre’s provings).
Психика и сознание
Emotional. Feel depressed or blue (twenty-fifth day). Feel gloomy, and want to sit quiet (seventh day). Feeling as if something was impending, which caused him to move about (ninth day). Disposed to be irritable (sixteenth day); irritable (nineteenth day); petulant disposition, and feeling of taciturnity gone (twenty-fourth day). Intellectual. Feel well; can study easily (third day); disposed to be reconciled to circumstances, favorable or unfavorable; feel like working hard; no undertaking too large for me (twelfth day). Mind dull; cannot think clearly (fifth day). Dull, at 8 p.m; stupid feeling, lasting through the day (second day). Felt dull and stupid (thirteenth day). After recommencing the taking of the drug, feel dull and stupid (fifth and seventh days). Dull, stupid, and forgetful. Dull and indisposed to study; cannot be interested (fourth day); still unable to bring himself to study (nineteenth day); cannot concentrate mind readily (fifth, sixth, ninth, twelfth, and fourteenth days). Dull and languid all day (ninth day). Stupid all day (fifth day). No disposition to attend to his accustomed business (fifth day). Requires an effort to attend to accustomed duties; feels dull; tries to write, but it requires and effort to form each word (second day). Feel much better doing nothing; do not wish to think, to read, or to exercise; eight days have passed since I quit taking the medicine, but still feel its effects (fourteenth day). Do not feel like thinking, or attending to any business (twenty first day); not disposed to attend to business (twenty- second day); disinclined to read or accomplish any business (twenty fifth day); unable to concentrate the mind on any subject requiring study; restless and unable to think (forty-second day); cannot think clearly and rapidly (forty-third day); more inclined to study, and apply myself to business; mind clear (fifty-third day). сannot concentrate mind on anything (eighth day). сannot concentrate the mind when reading (sixth day). сannot concentrate mind, or recall names, and indisposed to study or to speak to any one while the afternoon headaches last (twenty-fourth day). сould not think readily during the day, but this mind clear as usual (third day). сannot study (tenth day); mind clear (eleventh day); dull and listless all day (twelfth day); dull and listless; could not study, but on going into the open air and walking about, all the symptoms were relieved, and while walking he was bright enough, but when he came in and sat down, the same feeling of dulness returned (fourteenth day); mind not fit for study (sixteenth day); dull, but wants to sit or lie and not be disturbed; cannot study (nineteenth day); mind much clearer (twentieth and twenty first days). Forgetful (nineteenth day); disposition to forget entirely changed (twenty-fourth day). Head. сonfusion. сonfused feeling in the head (sixth day). Feeling of confusion through the head (ninth and fourteenth days). Vacant feeling in whole head (eighth day). General Head. Head feels dull (sixth and eighth days); head full and heavy (eleventh day). Head feels dull, as if he had taken cold (sixth day). Dull, through other (confused) feeling in head (fourteenth day); head feels dull (sixteenth day). Head dull and heavy; clear, in afternoon (twelfth day). Head feels dull and heavy, with aching pain in frontal region (third day). Head feels dull (twenty-first day); head feels dull and heavy, with some aching on vertex (twenty-second day). Slight dull feeling in head (fifth day). Head feels heavy (fourth and seventh days). Dull, heavy head all the evening, with slight nausea (fortieth day). Dull, heavy feeling in head, lasting about three hours, at 6 ; dull, heavy feeling in head, lasting five hours, after which the head ached violently, every motion of body aggravating it, even turning the head, and relieved by tying a handkerchief tightly around it, at 3 ; dull, heavy feeling in head, especially in the vertex, increasing in severity till I went to bed, and was made worse by stooping or moving head; the aching took away the appetite, at 3 (sixteenth day). Feeling of heat and fullness in whole head, at 8 (fourth day). Feeling of fullness in the head all morning (eighteenth day). Quite severe headache at intervals all morning (forty- seventh day). Violent headache; every time he awoke the whole head ached (fifth day). Heavy aching pain in ethmoid bone (fifth day). Head feels sore (eighteenth day). Throbbing in head on going upstairs (second day). Wavering floating sensation on turning head quickly (twenty seventh day). Every motion jars the brain (second day). Forehead. Dull feeling in frontal region, and at root of nose (ninth day). Heavy feeling in forehead (fifteenth day). Dull, heavy feeling in forehead, at top of head, with occasional sharp pains in side and top of head (thirteenth day). Numbness in forehead, in evening (twenty-seventh day). Very severe pain in frontal region, during the day (second day). Fullness in forehead, with throbbing in top of head, in afternoon (eighth day). Aching in forehead (fifteenth day). Headache in forehead and temples, lasting two days (sixth day). Severe frontal and temporal headache, coming between 2 and 3 , and lasting till 5 ; while the pain lasted the aching part was sore to touch, and during that time he was listless and absent-minded; at 10 , head free from pain and soreness, and mind clear (ninth day). Moderately severe aching in forehead and temples, worst in an above the orbits (seventh day); heavy feeling in head, but less pain than for two days past (eleventh day); less frontal headache than any day since proving began to develop symptoms (twelfth day). Quite a severe aching through temples and, worst from temple to temple, and lasting from time of waking in morning till 1 (twenty-fourth day). Violent frontal headache, with much perspiration, in afternoon (fifth day). Dull frontal headache (third, fifth, and eighth days); in morning, on waking (second day). Awoke with a dull frontal headache (second day); (twenty- fifth day). Dull, not severe, frontal headache (second day); headache all day, till since 4 it has ceased (third day); dull frontal headache (twelfth day); dull frontal headache for five or six days, coming on each day about 3 , and continuing steady till 9 or 10 , during which time felt dull and indisposed to study, or to speak to anyone (twenty-fourth day). Shooting pains through frontal region (twenty-fifth and twenty sixth days). Occasional shooting pains through forehead and right temple (third day). Temples. Pain in right temple, at 5 ; was stooping a good deal during the evening, and aggravated the pain; pain shifted to orbital region (forty-eighth day); bathed head in cold water without any benefit, at 8 ; ate a little at noon, which seemed to relieve, but the aching returned, in all its violence, on walking out in hot sun; very little pain in head, and do not feel so weak or sore, at 8 (fiftieth day); got up between 6 and 7 p.m, having some headache, which continued all day; free from headache, at 6 (fifty-first day). Severe pain, confined to right temple, on getting up in morning (which he formerly had, but supposed himself cured of from his having been free from it for a long time); while eating breakfast, had a severe pain through right temple, after which the headache grew less (fortieth day). Dull headache in right temple, at 8 p.m (forty-first day). Slight dull aching through temples, and across, above, and in the superciliary ridge, worse during forenoon. вoring headache, in the afternoon, in the temples, from without inwards, principally on right side, and extending to left, with nausea; head feels hot, but on placing hand on forehead, it seems cold; headache aggravated by heat, pressure, and tobacco-smoke (thirty-ninth day). Drawing pain in right temple, lasting a short time (second day). Throbbing of temporal artery (thirty-ninth day). Vertex. Dull pain in top of head, at 7.50 (twenty-first day); dull aching in top of head and above eyes (not severe), all day (twenty-fifth day); occasional dull headache on top of head, lasting about fifteen minutes at a time (forty-fifth day); headache on top of head, at 9.35 p.m (forty-sixth day); severe but dull aching on top of head, and also in the sides of the head; it lasted till after dinner (forty-ninth day). Severe sharp headache in top of head, and in forehead above eyes, worse above right eye, at 4.40 ; continues, and is increasing in severity, at 8.05 (forty- seventh day). Occiput. Feeling of pressure over each side of posterior inferior part of the occiput, as if in a photographer’s headrest (twenty- seventh day).
Голова, лицо и уши
Eye.
Objective. Eyes red (eighth day); a little red, but not swollen (twenty fourth day); a little red and watery (thirty-sixth day). Eyes looked swollen and bunged up (fiftieth day). Eyes swollen (orbital region), (eleventh, twelfth, and fourteenth days); eyes swollen and conjunctiva congested; external part of left eye more congested than right; conjunctiva of right eye also congested (fifth day after recommencing taking); eyes swollen; left one much congested and red (sixth day after recommencing taking); eyes inflamed and swollen; left worse than right (seventh day after recommencing taking); eyes painfully affected, swollen, red, and watery; left worse than right (eleventh day). Eyes swollen and painful (twenty-second day); worse immediately after rising (forty-third day); eyes swollen and congested (forty-fifth day); eyes slightly swollen and congested, at 9.35 p.m (forty- sixth day). Eyes somewhat swollen and agglutinated (thirty-eighth day). Eyes and orbital region much swollen and agglutinated (thirty eighth day). Eyes and orbital region much swollen and agglutinated, on waking in the morning (fourth day); eyes much congested, and whole orbital region very much swollen (fifth and eighth days); eyes congested and swollen; not so much congested in evening (ninth day); eyes slightly congested (tenth day). Eyes puffy, at 8 p.m (forty-first day). Eyes more puffy and congested (fourteenth day). Moderate congestion of vessels of white portion of eyes, but no disagreeable sensation in eyes (seventh day); eyes congested, especially in morning (tenth day); vessels of eyes congested, on waking in morning (eleventh day). Eyes much congested (third day); eyes congested (fourth day); eyes very much congested (sixth day). Sclerotica slightly congested (fourth day). A little whitish gum was seen in external canthus, in morning (twelfth and thirteenth days); eyes slightly gummed, in morning (twenty-fourth day). Subjective. Eyes feel tired and painful, especially in the sunlight (twenty first day); eyes have felt tired all day, and painful when reading or writing (twenty- fifth day). Eyes feel heavy (eighth day). Eyes felt heavy, in evening (after third dose, seventh day). Heaviness of the eyes, especially the right, in morning (second day); eyes heavy (thirty-ninth day). Eyes felt disagreeable on going into open air (twelfth day). Eyes sticky and sore (seventh day); eyes feel sticky, and a little gum is seen in the external canthus (eighteenth day). Reading by lamp or gaslight cannot be endured, for any considerable time, without giving discomfort (thirty- sixth day). Eyes painful, in morning (eleventh day). Eyes feel very painful (fiftieth day). Eyes burn and lachrymate slightly (fourth day). Eyes feel inflamed and swollen, with an accumulation of pasty matter in the canthus and on the lashes (third day). Eyes feel swollen (eighth day); in morning (third day). Eyes feel puffy (twelfth day). Looking at anything causes eyes to ache (seventh day). On looking long at an object the eyes ache for a time and require resting (fourteenth and twenty-fifth days). Dull aching pain in eyes, aggravated by sunlight (forty- first day). Eyes feel sore on pressure (second day); soreness and itching of eyes on moving them (third day). Eyes very painful to pressure, and pain aggravated by light (forty-eighth day). Inner canthi sore and red (third day); eyes sore; cannot read or write without pain in them (twenty-third day); eyes feel sore, on rising (thirty-eighth day); eyes feel sore and full at 9.30 p.m (forty-second day); eyes sore all day, especially when reading at 7.05 (forty-fifth day); eyes feel sore, at 9.35 p.m (forty sixth day); eyes feel worse than usual, quite painful; want of sleep last night has possibly made eyes feel worse; eyes somewhat painful when reading or writing at 8.10 (forty-eighth day); eyes unusually pain and sore; cannot read or write with any comfort; better by 10 o’clock; worse just after rising, but improve during day, at 8.55 p.m (forty-ninth day); eyes painful for about two hours after rising, and at times through the day, when reading or writing, or when exposed to bright sunlight (fiftieth day); eyes a little sore this morning (fifty-first day). Eyes irritable (eighth day); eyes feel as if he had lost his sleep (ninth day); eyes feel rather sorer, and light pains them (nineteenth day). Eyes a little irritable (fourth day); eyes feel sorer, and burn as if had been all day irritated by wood-smoke (fifth day); eyes smart as if smoked (sixth and seventh days); eyes feel sore on moving or rolling them, and the smarting continued (eighth day); eyes smart (twelfth day); eyes smart and feel disagreeable when exposed to the open air (fourteenth day); eyes smart and lachrymate very much in open air, and are congested (twentieth day); eyes sore and swollen, in morning on waking (twenty-third day); eyes sore (twenty-ninth day). Eyes smart and feel badly on reading for a time (twenty- sixth day). Eyes feel as if smoke were in the room (fifteenth day). Inner canthus itches, and feels pasty, in morning (second day). вrow and Orbit. Supraorbital region very much swollen (thirty-ninth day). Slight swelling of orbital region (seventh day); orbital region swollen (tenth day); whole orbital region swollen, on waking in morning, passed off gradually through the day (eleventh day). Slight oedema of orbital region, more marked in the right than the left (fourth day); orbital region somewhat swollen (eighth and eighteenth days); orbital region less swollen (fifteenth day). Slight oedema of orbital region, worse on right side (fourth day); some oedema of orbital region (sixth day); oedema of infraorbital region (seventh day); orbital region very much swollen, on waking (fourteenth, fifteenth, sixteenth, and seventeenth days); orbital region swollen, on waking, but the swelling passed of in about an hour after rising, leaving a slightly puffy appearance (eighteenth day); whole orbital region very much swollen (twenty-fourth day); orbital region some swollen, in mornings (twenty-ninth day). Orbital region much swollen (fortieth day). Dulness and very moderate aching through supraorbital region (seventeenth and eighteenth days). Pain over right eye (ninth day). Awoke with moderately severe pain, from one temple to the other, over orbits, which continued all day (fifteenth day) Aching through brow and orbits (eighth day); aching in supraorbital region rather worse, and extends farther up forehead, and most intense immediately above orbits (ninth day); severe pain in supraorbital region and temples, on waking; severe till 4 or 5 , then passing into the orbit posterior to and in the ball of the eye, with considerable photophobia; pain much severer in orbit than any other place, compelling him to lie down; never had this kind of pain before, except when taking the drug, on a former occasion; severe pain began to diminish about 7 , and by bedtime had almost passed away, leaving a dull, supraorbital pain (twenty-fourth day). Awoke in morning with very severe aching across brow, above orbits, with considerable vertigo on moving about, and a sensation of lightness or largeness of the head while sitting, continuing severe till 3 , when there was just enough pain to keep him conscious of it all the time (seventeenth day); about enough of the supraorbital headache to make him constantly aware that he has it (eighteenth day); frontal headache rather more severe (twenty-third day); first impression in morning produced by a severe pain in supraorbital region and temples, continuing very severe till 4 or 5 , when it passed into the orbit, posterior to an in the ball of the eye (twenty-fourth day). Heavy, disagreeably full feeling in orbital region, reaching to temples (fifth day). Dull pain over orbits, reaching into the temporal region (fourteenth day). Dull aching across orbits (sixteenth day). Occasional shooting pains above right eye (eighteenth day); feeling as of thickening of the structures within the lids, the right eye feeling worst (twenty-fourth day). Lids agglutinated, in morning (second and thirty-eighth days). Difficult keeping lids from closing (seventh day); lids disposed to close down, with inability to open eyes as wide as usual (ninth day). Stiffness of lids (twenty-seventh day). вurning of eyelids, in morning (second day). Eyelids feel swollen, particularly of right eye, and outer canthus worst; lower lid of right eye feels swollen and itchy, as if a stye would make its appearance, in morning (second day). Edges of eyelids itch and burn (fifteenth day). Lachrymal Apparatus. Lachrymation in open air (tenth and twelfth days); worse in morning (eighth day). Moderate lachrymation on going into open air (seventh and twelfth days); eyes lachrymate on looking steady at an object (fifteenth day); lachrymate very much in open air (twentieth day). Eyes very watery for some time after waking, in the morning (fortieth day). On going into open air, tears flowed freely, but this gradually wore off (thirty-eighth day); eyes water profusely when reading, at 9.35 p.m (forty- sixth day); tears secreted freely, at 8.55 p.m (forty-ninth day). сonjunctiva. Vessels of conjunctiva injected (fourth, fifth, and eleventh days). Vessels of conjunctiva fuller than usual, and white portion of eye has perceptibly yellowish tinge (fourth, fifth, and seventh days); palpebral vessels more congested, and the conjunctiva, on inner surface of lids an on balls, disposed to gather into folds, as the eyes are rolled back and forth (tenth day); vessels not so full, and sclerotica not so oedematous (thirteenth day); vessels of ball and inner side of lids are full, causing a feeling, on moving the ball, as of something granular between them (fifteenth day); vessels of conjunctiva congested (sixteenth day); inner surface of lower lid distinctly granular in appearance (twentieth day); vessels of ball and lid both largely congested (twenty fourth day); vessels of ball and lids perceptibly congested (twenty-ninth day). сonjunctiva congested, on waking in morning (second day); conjunctiva of uniform redness (third day); congested conjunctiva (fifth day). сonjunctival vessels congested (third day); conjunctiva slightly congested (fourth day). Vessels of conjunctiva somewhat congested, especially on rising this morning (there are no vessels visible usually in my eyes), (twenty-first day); vessels of conjunctiva congested (twenty fifth day); vessels of conjunctiva slightly congested (thirty eighth day); eyes slightly congested, at 9.30 p.m (forty-second day); conjunctiva congested, at 9.30 p.m (forty- third day); conjunctiva but slightly congested, at 12.10 (forty-eighth day); conjunctiva slightly congested, and jaundiced (fifty-first day). сonjunctival vessels moderately congested (ninth day); turgid (eighteenth day); vessels on inner surface of lid quite full, and vessels of globe less turgid (twentieth day). Palpebral lining membrane thickened and quite red, and as the eyes are rolled from side to side, or up and down, the lining membrane gathers in rolls between balls and lids, the left eye appearing the worst (twelfth day). вall. Stiffness of eyeballs (twenty- seventh day). Eyeballs seem large when closing lids over them, in morning, on waking (thirty-eighth day). Aching pain deep in eyeballs, after two hours’ reading; aggravated by opening eyes widely, and relieved by closing and resting them for a time (fortieth day). вalls sore and smarting (thirty-ninth day). Eyeballs sore on pressure, all day (twenty-fifth day). вalls sore to touch, or if pressed upon (fourteenth day). Eyeballs sore when closing lids, and pressing ball (fifth day after recommencing taking); left eye sore; continual scratching beneath lids on rolling the ball; light aggravates (sixth day after recommencing taking); continual scratching in left eye, as if sand was under outer part of upper lid (eleventh day after recommencing taking). Eyeballs feel sore and tender; pressure on ball does not produce pain directly, but when the pressure is removed the pain becomes severe, at 12.10 (forty-eighth day). Pupil. Pupils somewhat distended in morning (second day); pupils a little dilated (thirty-ninth day). Pupil of left eye much larger than that of the other (from two to three diameters), there seeming to be but little difference between the eyes in the power to discern objects, but on noticing closely, an object looked at has a misty appearance to both eyes; the distension of pupil passed off while walking, and did not return for the day, at 1 (fourteenth day); pupil of left eye very much enlarged, at 5 , and to some extent at 11 (seventeenth day); somewhat dilated (nineteenth day). Vision. Eyes dim, at 8 p.m (forty-first day). On looking long at an object, the sight becomes dim (fourteenth day); sight very much weakened from the condition of health (twenty-ninth day). Vision indistinct; frequent wiping of eyes for relief (fourth day); concentrated effort necessary for distinct vision (eleventh day); vision poor for long distances (twelfth day); vision remained [poor for a considerable time, and was the most lasting symptom (fifteenth day). Objects loose all distinctness and become blurred; dimness of vision on rising from a seat, at 11.55 p.m Slight photophobia (eighth day). сonsider- able photophobia (twenty-fourth day). Eyes sensitive to light (twenty-second day); a good deal of photophobia, at 12.10 (forty-eighth day). Flickering before eyes when closed, at 8 p.m (forty-first day). Eye symptoms worse in open air (ninth day).
Objective. Eyes red (eighth day); a little red, but not swollen (twenty fourth day); a little red and watery (thirty-sixth day). Eyes looked swollen and bunged up (fiftieth day). Eyes swollen (orbital region), (eleventh, twelfth, and fourteenth days); eyes swollen and conjunctiva congested; external part of left eye more congested than right; conjunctiva of right eye also congested (fifth day after recommencing taking); eyes swollen; left one much congested and red (sixth day after recommencing taking); eyes inflamed and swollen; left worse than right (seventh day after recommencing taking); eyes painfully affected, swollen, red, and watery; left worse than right (eleventh day). Eyes swollen and painful (twenty-second day); worse immediately after rising (forty-third day); eyes swollen and congested (forty-fifth day); eyes slightly swollen and congested, at 9.35 p.m (forty- sixth day). Eyes somewhat swollen and agglutinated (thirty-eighth day). Eyes and orbital region much swollen and agglutinated (thirty eighth day). Eyes and orbital region much swollen and agglutinated, on waking in the morning (fourth day); eyes much congested, and whole orbital region very much swollen (fifth and eighth days); eyes congested and swollen; not so much congested in evening (ninth day); eyes slightly congested (tenth day). Eyes puffy, at 8 p.m (forty-first day). Eyes more puffy and congested (fourteenth day). Moderate congestion of vessels of white portion of eyes, but no disagreeable sensation in eyes (seventh day); eyes congested, especially in morning (tenth day); vessels of eyes congested, on waking in morning (eleventh day). Eyes much congested (third day); eyes congested (fourth day); eyes very much congested (sixth day). Sclerotica slightly congested (fourth day). A little whitish gum was seen in external canthus, in morning (twelfth and thirteenth days); eyes slightly gummed, in morning (twenty-fourth day). Subjective. Eyes feel tired and painful, especially in the sunlight (twenty first day); eyes have felt tired all day, and painful when reading or writing (twenty- fifth day). Eyes feel heavy (eighth day). Eyes felt heavy, in evening (after third dose, seventh day). Heaviness of the eyes, especially the right, in morning (second day); eyes heavy (thirty-ninth day). Eyes felt disagreeable on going into open air (twelfth day). Eyes sticky and sore (seventh day); eyes feel sticky, and a little gum is seen in the external canthus (eighteenth day). Reading by lamp or gaslight cannot be endured, for any considerable time, without giving discomfort (thirty- sixth day). Eyes painful, in morning (eleventh day). Eyes feel very painful (fiftieth day). Eyes burn and lachrymate slightly (fourth day). Eyes feel inflamed and swollen, with an accumulation of pasty matter in the canthus and on the lashes (third day). Eyes feel swollen (eighth day); in morning (third day). Eyes feel puffy (twelfth day). Looking at anything causes eyes to ache (seventh day). On looking long at an object the eyes ache for a time and require resting (fourteenth and twenty-fifth days). Dull aching pain in eyes, aggravated by sunlight (forty- first day). Eyes feel sore on pressure (second day); soreness and itching of eyes on moving them (third day). Eyes very painful to pressure, and pain aggravated by light (forty-eighth day). Inner canthi sore and red (third day); eyes sore; cannot read or write without pain in them (twenty-third day); eyes feel sore, on rising (thirty-eighth day); eyes feel sore and full at 9.30 p.m (forty-second day); eyes sore all day, especially when reading at 7.05 (forty-fifth day); eyes feel sore, at 9.35 p.m (forty sixth day); eyes feel worse than usual, quite painful; want of sleep last night has possibly made eyes feel worse; eyes somewhat painful when reading or writing at 8.10 (forty-eighth day); eyes unusually pain and sore; cannot read or write with any comfort; better by 10 o’clock; worse just after rising, but improve during day, at 8.55 p.m (forty-ninth day); eyes painful for about two hours after rising, and at times through the day, when reading or writing, or when exposed to bright sunlight (fiftieth day); eyes a little sore this morning (fifty-first day). Eyes irritable (eighth day); eyes feel as if he had lost his sleep (ninth day); eyes feel rather sorer, and light pains them (nineteenth day). Eyes a little irritable (fourth day); eyes feel sorer, and burn as if had been all day irritated by wood-smoke (fifth day); eyes smart as if smoked (sixth and seventh days); eyes feel sore on moving or rolling them, and the smarting continued (eighth day); eyes smart (twelfth day); eyes smart and feel disagreeable when exposed to the open air (fourteenth day); eyes smart and lachrymate very much in open air, and are congested (twentieth day); eyes sore and swollen, in morning on waking (twenty-third day); eyes sore (twenty-ninth day). Eyes smart and feel badly on reading for a time (twenty- sixth day). Eyes feel as if smoke were in the room (fifteenth day). Inner canthus itches, and feels pasty, in morning (second day). вrow and Orbit. Supraorbital region very much swollen (thirty-ninth day). Slight swelling of orbital region (seventh day); orbital region swollen (tenth day); whole orbital region swollen, on waking in morning, passed off gradually through the day (eleventh day). Slight oedema of orbital region, more marked in the right than the left (fourth day); orbital region somewhat swollen (eighth and eighteenth days); orbital region less swollen (fifteenth day). Slight oedema of orbital region, worse on right side (fourth day); some oedema of orbital region (sixth day); oedema of infraorbital region (seventh day); orbital region very much swollen, on waking (fourteenth, fifteenth, sixteenth, and seventeenth days); orbital region swollen, on waking, but the swelling passed of in about an hour after rising, leaving a slightly puffy appearance (eighteenth day); whole orbital region very much swollen (twenty-fourth day); orbital region some swollen, in mornings (twenty-ninth day). Orbital region much swollen (fortieth day). Dulness and very moderate aching through supraorbital region (seventeenth and eighteenth days). Pain over right eye (ninth day). Awoke with moderately severe pain, from one temple to the other, over orbits, which continued all day (fifteenth day) Aching through brow and orbits (eighth day); aching in supraorbital region rather worse, and extends farther up forehead, and most intense immediately above orbits (ninth day); severe pain in supraorbital region and temples, on waking; severe till 4 or 5 , then passing into the orbit posterior to and in the ball of the eye, with considerable photophobia; pain much severer in orbit than any other place, compelling him to lie down; never had this kind of pain before, except when taking the drug, on a former occasion; severe pain began to diminish about 7 , and by bedtime had almost passed away, leaving a dull, supraorbital pain (twenty-fourth day). Awoke in morning with very severe aching across brow, above orbits, with considerable vertigo on moving about, and a sensation of lightness or largeness of the head while sitting, continuing severe till 3 , when there was just enough pain to keep him conscious of it all the time (seventeenth day); about enough of the supraorbital headache to make him constantly aware that he has it (eighteenth day); frontal headache rather more severe (twenty-third day); first impression in morning produced by a severe pain in supraorbital region and temples, continuing very severe till 4 or 5 , when it passed into the orbit, posterior to an in the ball of the eye (twenty-fourth day). Heavy, disagreeably full feeling in orbital region, reaching to temples (fifth day). Dull pain over orbits, reaching into the temporal region (fourteenth day). Dull aching across orbits (sixteenth day). Occasional shooting pains above right eye (eighteenth day); feeling as of thickening of the structures within the lids, the right eye feeling worst (twenty-fourth day). Lids agglutinated, in morning (second and thirty-eighth days). Difficult keeping lids from closing (seventh day); lids disposed to close down, with inability to open eyes as wide as usual (ninth day). Stiffness of lids (twenty-seventh day). вurning of eyelids, in morning (second day). Eyelids feel swollen, particularly of right eye, and outer canthus worst; lower lid of right eye feels swollen and itchy, as if a stye would make its appearance, in morning (second day). Edges of eyelids itch and burn (fifteenth day). Lachrymal Apparatus. Lachrymation in open air (tenth and twelfth days); worse in morning (eighth day). Moderate lachrymation on going into open air (seventh and twelfth days); eyes lachrymate on looking steady at an object (fifteenth day); lachrymate very much in open air (twentieth day). Eyes very watery for some time after waking, in the morning (fortieth day). On going into open air, tears flowed freely, but this gradually wore off (thirty-eighth day); eyes water profusely when reading, at 9.35 p.m (forty- sixth day); tears secreted freely, at 8.55 p.m (forty-ninth day). сonjunctiva. Vessels of conjunctiva injected (fourth, fifth, and eleventh days). Vessels of conjunctiva fuller than usual, and white portion of eye has perceptibly yellowish tinge (fourth, fifth, and seventh days); palpebral vessels more congested, and the conjunctiva, on inner surface of lids an on balls, disposed to gather into folds, as the eyes are rolled back and forth (tenth day); vessels not so full, and sclerotica not so oedematous (thirteenth day); vessels of ball and inner side of lids are full, causing a feeling, on moving the ball, as of something granular between them (fifteenth day); vessels of conjunctiva congested (sixteenth day); inner surface of lower lid distinctly granular in appearance (twentieth day); vessels of ball and lid both largely congested (twenty fourth day); vessels of ball and lids perceptibly congested (twenty-ninth day). сonjunctiva congested, on waking in morning (second day); conjunctiva of uniform redness (third day); congested conjunctiva (fifth day). сonjunctival vessels congested (third day); conjunctiva slightly congested (fourth day). Vessels of conjunctiva somewhat congested, especially on rising this morning (there are no vessels visible usually in my eyes), (twenty-first day); vessels of conjunctiva congested (twenty fifth day); vessels of conjunctiva slightly congested (thirty eighth day); eyes slightly congested, at 9.30 p.m (forty-second day); conjunctiva congested, at 9.30 p.m (forty- third day); conjunctiva but slightly congested, at 12.10 (forty-eighth day); conjunctiva slightly congested, and jaundiced (fifty-first day). сonjunctival vessels moderately congested (ninth day); turgid (eighteenth day); vessels on inner surface of lid quite full, and vessels of globe less turgid (twentieth day). Palpebral lining membrane thickened and quite red, and as the eyes are rolled from side to side, or up and down, the lining membrane gathers in rolls between balls and lids, the left eye appearing the worst (twelfth day). вall. Stiffness of eyeballs (twenty- seventh day). Eyeballs seem large when closing lids over them, in morning, on waking (thirty-eighth day). Aching pain deep in eyeballs, after two hours’ reading; aggravated by opening eyes widely, and relieved by closing and resting them for a time (fortieth day). вalls sore and smarting (thirty-ninth day). Eyeballs sore on pressure, all day (twenty-fifth day). вalls sore to touch, or if pressed upon (fourteenth day). Eyeballs sore when closing lids, and pressing ball (fifth day after recommencing taking); left eye sore; continual scratching beneath lids on rolling the ball; light aggravates (sixth day after recommencing taking); continual scratching in left eye, as if sand was under outer part of upper lid (eleventh day after recommencing taking). Eyeballs feel sore and tender; pressure on ball does not produce pain directly, but when the pressure is removed the pain becomes severe, at 12.10 (forty-eighth day). Pupil. Pupils somewhat distended in morning (second day); pupils a little dilated (thirty-ninth day). Pupil of left eye much larger than that of the other (from two to three diameters), there seeming to be but little difference between the eyes in the power to discern objects, but on noticing closely, an object looked at has a misty appearance to both eyes; the distension of pupil passed off while walking, and did not return for the day, at 1 (fourteenth day); pupil of left eye very much enlarged, at 5 , and to some extent at 11 (seventeenth day); somewhat dilated (nineteenth day). Vision. Eyes dim, at 8 p.m (forty-first day). On looking long at an object, the sight becomes dim (fourteenth day); sight very much weakened from the condition of health (twenty-ninth day). Vision indistinct; frequent wiping of eyes for relief (fourth day); concentrated effort necessary for distinct vision (eleventh day); vision poor for long distances (twelfth day); vision remained [poor for a considerable time, and was the most lasting symptom (fifteenth day). Objects loose all distinctness and become blurred; dimness of vision on rising from a seat, at 11.55 p.m Slight photophobia (eighth day). сonsider- able photophobia (twenty-fourth day). Eyes sensitive to light (twenty-second day); a good deal of photophobia, at 12.10 (forty-eighth day). Flickering before eyes when closed, at 8 p.m (forty-first day). Eye symptoms worse in open air (ninth day).