Compatibility «Indapamide» and «Furosemide»
Between «Indapamide» and «Furosemide» found 3 dangerous and 10 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Furosemide |
✘Indapamide Analogs | |
✘Furosemide Analogs |
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Interactions Indapamide with Furosemide
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Dangerous interactions
In chronic heart failure, treatment with ACE inhibitors should begin with the lowest doses, with a possible preliminary reduction in doses of diuretics. Functional renal insufficiency, which can occur against the background of taking diuretics, especially 'loop' ones, while prescribing metformin increases the risk of lactic acidosis. Dehydration of the body while taking diuretic drugs increases the risk of acute renal failure, especially when using high doses of iodine-containing contrast agents. -
Negative interactions
The use of indapamide can sum up or potentiate the effect of other antihypertensive drugs. In limited controlled studies comparing the effects of indapamide in combination with other antihypertensive drugs with the effects of other antihypertensive drugs used as monotherapy, there were no noticeable changes in the nature or frequency of adverse reactions associated with combination therapy. If necessary, diuretic drugs can be used in combination with lithium preparations, while carefully selecting the dose of drugs, regularly monitoring the concentration of lithium in blood plasma and selecting the dose of the drug accordingly. Patients with arterial hypertension and possibly reduced sodium content in blood plasma due to taking diuretics should:. 3 days before the start of treatment with an ACE inhibitor, stop taking diuretics; in the future, if necessary, taking a non-potassium-sparing diuretic can be resumed;. if discontinuation of diuretics is not possible, then ACE inhibitor therapy should be started at low doses, followed by a gradual increase in the dose if necessary. Blood pressure should be monitored and, if necessary, the doses of antihypertensive drugs should be adjusted. Under the influence of furosemide, the effect of ACE inhibitors and antihypertensive agents, warfarin, diazoxide, theophylline increases. Risperidone - care must be taken, carefully weighing the risk-benefit ratio, before deciding on the use of a combination of risperidone with furosemide or other strong diuretics, as there has been an increase in mortality in elderly patients with dementia treated simultaneously with risperidone and furosemide. Antihypertensive drugs, diuretics or other drugs capable of lowering blood pressure - when combined with furosemide, a more pronounced decrease in blood pressure is expected.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,974,420 possible combinations of drugs and their components were found 412,510 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-05-02
Category - medicine