Compatibility «Mycophenolate mofetil» and «Pantoprazole»
Between «Mycophenolate mofetil» and «Pantoprazole» found 1 dangerous and 3 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Pantoprazole |
✘Mycophenolate mofetil Analogs | |
✘Pantoprazole Analogs |
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Interactions Mycophenolate mofetil with Pantoprazole
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Dangerous interactions
The clinical significance of reducing the effect of mycophenolic acid on organ rejection in transplant patients receiving pantoprazole in the form of injections and mycophenolate mofetil has not been established. -
Negative interactions
When Mycophenolate mofetil-TL was co-administered with antacids (aluminum and magnesium hydroxide) and proton pump inhibitors (PPIs) (lansoprazole and pantoprazole), a decrease in the concentration of IFC was observed. Mycophenolate mofetil: Co-administration of pantoprazole to healthy subjects and transplant patients receiving mycophenolate mofetil has been reported to reduce the effect of the active metabolite mycophenolic acid, possibly due to a decrease in the solubility of mycophenolate mofetil with an increase in the pH of gastric juice. Caution should be exercised when using pantoprazole in transplant patients receiving mycophenolate mofetil. -
No interactions
It is compatible with drugs metabolized with the participation of the cytochrome P450 enzyme system: phenazepam, diazepam, digoxin, theophylline, carbamazepine, diclofenac, naproxen, piroxicam, phenytoin, warfarin, nifedipine, metoprolol, ethanol. In other in vivo studies, there was no clinically significant interaction of pantoprazole with digoxin, ethanol, glyburide, phenazone, caffeine, metronidazole and amoxicillin. -
Unclear interactions
Aitacids and proton pump inhibitors. Drugs whose absorption depends on the pH of gastric juice (for example, iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole).
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
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Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,974,420 possible combinations of drugs and their components were found 412,510 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-05-02
Category - medicine